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Query: NC_012659:4853640:4865570 Bacillus anthracis str. A0248, complete genome

Start: 4865570, End: 4865815, Length: 246

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008600:4868000:487873948787394878993255Bacillus thuringiensis str. Al Hakam, complete genomeglutaredoxin family protein2e-39160
NC_007530:4853740:486567048656704865915246Bacillus anthracis str. 'Ames Ancestor', complete genomeglutaredoxin family protein2e-39160
NC_003997:4852332:486554448655444865789246Bacillus anthracis str. Ames, complete genomeglutaredoxin family protein2e-39160
NC_005945:4854951:486688148668814867126246Bacillus anthracis str. Sterne, complete genomeglutaredoxin family protein2e-39160
NC_012472:4867210:488051548805154880760246Bacillus cereus 03BB102, complete genomeglutaredoxin family protein2e-39160
NC_011773:4914601:492803849280384928283246Bacillus cereus AH820 chromosome, complete genomeglutaredoxin family protein2e-39160
NC_012581:4856620:486799348679934868238246Bacillus anthracis str. CDC 684 chromosome, complete genomeglutaredoxin family protein2e-39160
NC_016779:4825599:483889048388904839135246Bacillus cereus F837/76 chromosome, complete genomeglutaredoxin family protein2e-39160
NC_006274:4910465:492391149239114924156246Bacillus cereus E33L, complete genomeglutaredoxin family protein1e-38158
NC_005957:4850659:487138948713894871634246Bacillus thuringiensis serovar konkukian str. 97-27, completeglutaredoxin family protein1e-38158
NC_004722:5027762:504487250448725045117246Bacillus cereus ATCC 14579, complete genomeGlutaredoxin2e-38157
NC_011725:5043198:505656950565695056814246Bacillus cereus B4264 chromosome, complete genomeglutaredoxin family protein2e-38157
NC_017208:5096759:511014351101435110388246Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeglutaredoxin2e-38157
NC_016771:4821000:483194548319454832190246Bacillus cereus NC7401, complete genomeglutaredoxin family protein4e-38156
NC_011658:4866184:487962248796224879867246Bacillus cereus AH187 chromosome, complete genomeglutaredoxin family protein4e-38156
NC_003909:4831000:484195748419574842202246Bacillus cereus ATCC 10987, complete genomeglutaredoxin family protein4e-38156
NC_011772:4994500:501033450103345010579246Bacillus cereus G9842, complete genomeglutaredoxin family protein1e-37155
NC_014171:4933200:494629449462944946539246Bacillus thuringiensis BMB171 chromosome, complete genomeglutaredoxin7e-38155
NC_014335:4800500:481654748165474816792246Bacillus cereus biovar anthracis str. CI chromosome, completeglutaredoxin family protein5e-38155
NC_017200:4915780:492906749290674929312246Bacillus thuringiensis serovar finitimus YBT-020 chromosome,glutaredoxin family protein2e-37154
NC_011969:4802500:481325348132534813498246Bacillus cereus Q1 chromosome, complete genomeglutaredoxin family protein3e-37153
NC_010184:4879552:489765248976524897897246Bacillus weihenstephanensis KBAB4, complete genomeglutaredoxin 24e-36149
NC_009674:3732000:374438737443873744632246Bacillus cytotoxicus NVH 391-98 chromosome, complete genomeglutaredoxin8e-26115