Pre_GI: BLASTP Hits

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Query: NC_012659:4674235:4683401 Bacillus anthracis str. A0248, complete genome

Start: 4683401, End: 4683907, Length: 507

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016779:4645155:465633746563374656843507Bacillus cereus F837/76 chromosome, complete genomeNudix hydrolase2e-93340
NC_005945:4670978:468459846845984685104507Bacillus anthracis str. Sterne, complete genomemutT/nudix family protein2e-93340
NC_014335:4622500:463369046336904634196507Bacillus cereus biovar anthracis str. CI chromosome, completeMutT/Nudix family protein2e-93340
NC_005957:4680089:468932446893244689830507Bacillus thuringiensis serovar konkukian str. 97-27, completeNudix hydrolase2e-93340
NC_008600:4687500:469871446987144699220507Bacillus thuringiensis str. Al Hakam, complete genomeMutT/NUDIX family protein2e-93340
NC_012472:4691251:470243347024334702939507Bacillus cereus 03BB102, complete genomemutT/nudix family protein2e-93340
NC_007530:4674335:468350146835014684007507Bacillus anthracis str. 'Ames Ancestor', complete genomemutt/nudix family protein2e-93340
NC_003997:4674209:468337546833754683881507Bacillus anthracis str. Ames, complete genomemutT/nudix family protein2e-93340
NC_011773:4732457:474364047436404744146507Bacillus cereus AH820 chromosome, complete genomemutT/nudix family protein2e-93340
NC_006274:4742489:475367147536714754177507Bacillus cereus E33L, complete genomeNudix hydrolase1e-92338
NC_011969:4613430:462458946245894625095507Bacillus cereus Q1 chromosome, complete genomemutt/nudix family protein3e-91333
NC_017200:4697500:470818347081834708689507Bacillus thuringiensis serovar finitimus YBT-020 chromosome,mutT/nudix family protein3e-91333
NC_017208:4887334:488999048899904890496507Bacillus thuringiensis serovar chinensis CT-43 chromosome, completephosphohydrolase1e-85314
NC_014171:4740500:475039047503904750896507Bacillus thuringiensis BMB171 chromosome, complete genomeMutT/NUDIX family protein phosphohydrolase2e-85313
NC_004722:4824818:483444548344454834951507Bacillus cereus ATCC 14579, complete genomePhosphohydrolase (MutT/nudix family protein)2e-85313
NC_011725:4870223:487445448744544874960507Bacillus cereus B4264 chromosome, complete genomemutT/nudix family protein9e-85311
NC_011658:4672000:468422546842254684731507Bacillus cereus AH187 chromosome, complete genomemutT/nudix family protein2e-82304
NC_013406:5066769:5080674508067450816991026Paenibacillus sp. Y412MC10 chromosome, complete genomehypothetical protein3e-1064.3
NC_007777:135222:161702161702162172471Frankia sp. CcI3, complete genomeNUDIX hydrolase2e-0961.6
NC_015635:811500:817054817054817476423Microlunatus phosphovorus NM-1, complete genomeputative hydrolase3e-0858.2
NC_008595:3914463:392772739277273928194468Mycobacterium avium 104, complete genomenudix hydrolase4e-0857.8
NC_009439:3770282:380120938012093801772564Pseudomonas mendocina ymp, complete genomeNUDIX hydrolase3e-0857.8
NC_014002:403180:408129408129408545417Methanohalophilus mahii DSM 5219 chromosome, complete genomeNUDIX hydrolase3e-0857.8
NC_009921:6421387:642320864232086423678471Frankia sp. EAN1pec, complete genomeNUDIX hydrolase2e-0755.1
NC_016947:2380500:243760724376072438074468Mycobacterium intracellulare MOTT-02 chromosome, complete genomeNUDIX hydrolase3e-0754.7
NC_008146:3349415:336220633622063362673468Mycobacterium sp. MCS, complete genomeNUDIX hydrolase3e-0754.7
NC_009077:3323291:333608233360823336549468Mycobacterium sp. JLS, complete genomeNUDIX hydrolase3e-0754.7
NC_008705:3377697:339048833904883390955468Mycobacterium sp. KMS, complete genomeNUDIX hydrolase3e-0754.7
NC_013235:508585:5230335230335246251593Nakamurella multipartita DSM 44233, complete genomeprotein of unknown function DUF11524e-0753.9
NC_016114:3575955:358400335840033584467465Streptomyces flavogriseus ATCC 33331 chromosome, complete genomeNUDIX hydrolase8e-0753.1
NC_020410:495184:5312675312675325051239Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completeUncharacterized 45.4 kDa protein in thiaminase I 5'region (Protein nagD homolog)2e-0652
NC_009725:496443:5486775486775499121236Bacillus amyloliquefaciens FZB42, complete genomehypothetical protein2e-0652
NC_008062:81338:872898728987750462Burkholderia cenocepacia AU 1054 chromosome 3, complete sequenceNUDIX hydrolase2e-0652
NC_019673:1420198:142711114271111427626516Saccharothrix espanaensis DSM 44229 complete genomeNUDIX family hydrolase3e-0651.6
NC_016948:678939:688874688874689302429Mycobacterium intracellulare MOTT-64 chromosome, complete genomehypothetical protein2e-0651.6
NC_015574:2355500:236358323635832363996414Methanobacterium sp. SWAN-1 chromosome, complete genomeNUDIX hydrolase2e-0651.6
NC_008544:55451:651086510865539432Burkholderia cenocepacia HI2424 chromosome 3, complete sequenceNUDIX hydrolase2e-0651.6
NC_016109:4645905:465854046585404658956417Kitasatospora setae KM-6054, complete genomeputative hydrolase2e-0651.6
NC_021177:4124839:413835541383554138819465Streptomyces fulvissimus DSM 40593, complete genomeNUDIX hydrolase3e-0651.2
NC_017904:666285:674377674377674808432Mycobacterium sp. MOTT36Y chromosome, complete genomehypothetical protein3e-0651.2
NC_010612:3813481:381430538143053814772468Mycobacterium marinum M, complete genomehypothetical protein3e-0651.2
NC_020133:5485528:549918654991865499614429Mycobacterium liflandii 128FXT, complete genomehypothetical protein5e-0650.4
NC_007168:2448422:245294424529442453363420Staphylococcus haemolyticus JCSC1435, complete genomehypothetical protein8e-0649.7
NC_013926:1037681:104213810421381042848711Aciduliprofundum boonei T469 chromosome, complete genomeNUDIX hydrolase8e-0649.7
NC_013929:5248000:526069552606955261102408Streptomyces scabiei 87.22 chromosome, complete genomeNUDIX hydrolase1e-0549.3