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Query: NC_012659:4674235:4683087 Bacillus anthracis str. A0248, complete genome

Start: 4683087, End: 4683404, Length: 318

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016779:4645155:465602346560234656340318Bacillus cereus F837/76 chromosome, complete genomehypothetical protein9e-39158
NC_011773:4732457:474332647433264743643318Bacillus cereus AH820 chromosome, complete genomehypothetical protein9e-39158
NC_005957:4680089:468901046890104689327318Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein9e-39158
NC_014335:4622500:463337646333764633693318Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein9e-39158
NC_005945:4670978:468428446842844684601318Bacillus anthracis str. Sterne, complete genomehypothetical protein9e-39158
NC_006274:4742489:475335747533574753674318Bacillus cereus E33L, complete genomehypothetical protein9e-39158
NC_012472:4691251:470211947021194702436318Bacillus cereus 03BB102, complete genomehypothetical protein9e-39158
NC_003997:4674209:468306146830614683351291Bacillus anthracis str. Ames, complete genomehypothetical protein1e-38157
NC_007530:4674335:468318746831874683477291Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein1e-38157
NC_017200:4697500:470786947078694708186318Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein5e-38156
NC_011658:4672000:468391146839114684228318Bacillus cereus AH187 chromosome, complete genomehypothetical protein5e-38156
NC_017208:4887334:488967648896764889993318Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein5e-38155
NC_011725:4870223:487414048741404874457318Bacillus cereus B4264 chromosome, complete genomehypothetical protein5e-38155
NC_004722:4824818:483413148341314834448318Bacillus cereus ATCC 14579, complete genomehypothetical protein5e-38155
NC_011969:4613430:462427546242754624562288Bacillus cereus Q1 chromosome, complete genomehypothetical protein8e-38155
NC_014171:4740500:475007647500764750294219Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein3e-34143
NC_014479:3079855:308278030827803083100321Bacillus subtilis subsp. spizizenii str. W23 chromosome, completehypothetical protein7e-1682.4