Pre_GI: BLASTP Hits

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Query: NC_012659:4674235:4674714 Bacillus anthracis str. A0248, complete genome

Start: 4674714, End: 4675457, Length: 744

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005945:4670978:467591146759114676654744Bacillus anthracis str. Sterne, complete genomehypothetical protein9e-133472
NC_007530:4674335:467481446748144675557744Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein9e-133472
NC_003997:4674209:467468846746884675431744Bacillus anthracis str. Ames, complete genomehypothetical protein9e-133472
NC_011773:4732457:473599747359974736740744Bacillus cereus AH820 chromosome, complete genomehypothetical protein2e-132471
NC_005957:4680089:468008946800894680832744Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein2e-132471
NC_016779:4645155:464869546486954649438744Bacillus cereus F837/76 chromosome, complete genomehypothetical protein8e-132469
NC_006274:4742489:474602847460284746771744Bacillus cereus E33L, complete genomehypothetical protein6e-132469
NC_008600:4687500:469107246910724691815744Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein3e-131467
NC_012472:4691251:469479146947914695534744Bacillus cereus 03BB102, complete genomehypothetical protein9e-131466
NC_014335:4622500:462604746260474626790744Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein4e-130463
NC_011658:4672000:467556246755624676305744Bacillus cereus AH187 chromosome, complete genomehypothetical protein1e-129462
NC_011969:4613430:461697346169734617716744Bacillus cereus Q1 chromosome, complete genomehypothetical protein5e-129460
NC_017200:4697500:470056647005664701309744Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein1e-124445
NC_004722:4824818:482671348267134827456744Bacillus cereus ATCC 14579, complete genomehypothetical Cytosolic Protein1e-122439
NC_014171:4740500:474265947426594743402744Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein2e-122438
NC_009718:1207360:123281712328171233560744Fervidobacterium nodosum Rt17-B1, complete genomehypothetical protein7e-1890.9
NC_014483:195321:2146152146152157241110Paenibacillus polymyxa E681 chromosome, complete genomehypothetical protein2e-1066.2
NC_016776:2516149:252041325204132521267855Bacteroides fragilis 638R, complete genomehypothetical protein2e-0860.1
NC_006347:2375480:237974423797442380598855Bacteroides fragilis YCH46, complete genomehypothetical protein2e-0860.1
NC_009089:4177117:418004941800494180792744Clostridium difficile 630, complete genomehypothetical protein6e-0858.2
NC_017179:3984000:398560439856043986347744Clostridium difficile BI1, complete genomehypothetical protein1e-0757
NC_010831:788500:807159807159808004846Chlorobium phaeobacteroides BS1, complete genomehypothetical protein2e-0756.6
NC_009495:1516000:152462615246261525348723Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein2e-0756.2
NC_010520:1586000:159707615970761597798723Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein8e-0754.3
NC_012658:1052957:1061837106183710643112475Clostridium botulinum Ba4 str. 657 chromosome, complete genomeKWG repeat-containing protein5e-0651.6