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Query: NC_012659:3692803:3698498 Bacillus anthracis str. A0248, complete genome

Start: 3698498, End: 3698752, Length: 255

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016779:3660000:366432936643293664583255Bacillus cereus F837/76 chromosome, complete genomehypothetical protein7e-40162
NC_007530:3694940:369859836985983698852255Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein7e-40162
NC_006274:3773335:377953237795323779786255Bacillus cereus E33L, complete genomehypothetical protein7e-40162
NC_003997:3692776:369847136984713698725255Bacillus anthracis str. Ames, complete genomehypothetical protein7e-40162
NC_012472:3743473:374649737464973746751255Bacillus cereus 03BB102, complete genomehypothetical protein7e-40162
NC_005945:3693471:369916636991663699420255Bacillus anthracis str. Sterne, complete genomehypothetical protein7e-40162
NC_011773:3729500:373388137338813734135255Bacillus cereus AH820 chromosome, complete genomehypothetical protein7e-40162
NC_017208:3897253:390027939002793900533255Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein7e-39159
NC_005957:3716487:372066737206673720921255Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein7e-39159
NC_011658:3680829:368704636870463687300255Bacillus cereus AH187 chromosome, complete genomehypothetical protein1e-38158
NC_011969:3627980:363100636310063631260255Bacillus cereus Q1 chromosome, complete genomehypothetical protein1e-38158
NC_016771:3633327:363954436395443639798255Bacillus cereus NC7401, complete genomehypothetical protein1e-38158
NC_014335:3645500:364984836498483650102255Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein9e-39158
NC_017200:3737185:374334037433403743594255Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein2e-38157
NC_011772:3863166:386938538693853869639255Bacillus cereus G9842, complete genomehypothetical protein7e-38155
NC_003909:3671468:367708936770893677343255Bacillus cereus ATCC 10987, complete genomehypothetical protein2e-37154
NC_014171:3779956:378413637841363784390255Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein5e-37152
NC_010184:3757000:375916437591643759418255Bacillus weihenstephanensis KBAB4, complete genomehypothetical protein5e-37152
NC_004722:3855326:386099838609983861243246Bacillus cereus ATCC 14579, complete genomehypothetical Membrane Spanning Protein1e-36151
NC_011725:3897450:390331739033173903571255Bacillus cereus B4264 chromosome, complete genomehypothetical protein2e-36151
NC_009674:2624817:263004926300492630303255Bacillus cytotoxicus NVH 391-98 chromosome, complete genomehypothetical protein3e-36150
NC_012581:519969:539882539882540088207Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein2e-24110