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Query: NC_012659:3579999:3595557 Bacillus anthracis str. A0248, complete genome

Start: 3595557, End: 3595805, Length: 249

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008600:3611038:362235436223543622617264Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein2e-41167
NC_003997:3579972:359553035955303595778249Bacillus anthracis str. Ames, complete genomehypothetical protein2e-41167
NC_014335:3531931:354637935463793546627249Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein2e-41167
NC_005957:3602744:361719936171993617447249Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein2e-41167
NC_005945:3581776:359623135962313596479249Bacillus anthracis str. Sterne, complete genomehypothetical protein2e-41167
NC_006274:3661194:367608236760823676330249Bacillus cereus E33L, complete genomehypothetical protein2e-41167
NC_007530:3581202:359565735956573595905249Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein2e-41167
NC_011773:3615998:363045236304523630700249Bacillus cereus AH820 chromosome, complete genomehypothetical protein2e-41167
NC_012581:639329:642783642783643031249Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein2e-41167
NC_016771:3520522:353609635360963536344249Bacillus cereus NC7401, complete genomehypothetical protein2e-41167
NC_017200:3622838:363729036372903637538249Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein2e-41167
NC_011772:3705878:372396837239683724216249Bacillus cereus G9842, complete genomehypothetical protein2e-40164
NC_012472:3625800:364036136403613640609249Bacillus cereus 03BB102, complete genomehypothetical protein1e-40164
NC_014171:3661512:367959236795923679840249Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein6e-40162
NC_011725:3785769:380032938003293800577249Bacillus cereus B4264 chromosome, complete genomehypothetical protein6e-40162
NC_009253:3317533:333373433337343333997264Desulfotomaculum reducens MI-1 chromosome, complete genomehypothetical protein7e-0959.3
NC_021184:3793285:379533237953323795592261Desulfotomaculum gibsoniae DSM 7213, complete genomeProtein of unknown function (DUF3243)2e-0651.6