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Query: NC_012659:3579999:3580667 Bacillus anthracis str. A0248, complete genome

Start: 3580667, End: 3581098, Length: 432

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_020410:1684192:168572416857241686155432Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completemaster regulator for biofilm formation, YmcA2e-47187
NC_003997:3579972:358064035806403581071432Bacillus anthracis str. Ames, complete genomehypothetical protein1e-77287
NC_012472:3625800:362580036258003626231432Bacillus cereus 03BB102, complete genomehypothetical protein1e-77287
NC_011725:3785769:378576937857693786200432Bacillus cereus B4264 chromosome, complete genomehypothetical protein5e-76282
NC_006274:3661194:366119436611943661625432Bacillus cereus E33L, complete genomehypothetical protein1e-77287
NC_011772:3705878:370940637094063709837432Bacillus cereus G9842, complete genomehypothetical protein2e-76283
NC_016771:3520522:352118935211893521620432Bacillus cereus NC7401, complete genomehypothetical protein1e-77287
NC_014171:3661512:366503336650333665464432Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein5e-76282
NC_010184:3590895:359770235977023598133432Bacillus weihenstephanensis KBAB4, complete genomeprotein of unknown function DUF13331e-75281
NC_016052:2201211:221920122192012219587387Tetragenococcus halophilus NBRC 12172, complete genomehypothetical protein2e-0651.2