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Query: NC_012659:1008028:1018913 Bacillus anthracis str. A0248, complete genome

Start: 1018913, End: 1019077, Length: 165

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005957:1037205:104760710476071047816210Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein8e-1579
NC_006274:1040836:105171610517161051925210Bacillus cereus E33L, complete genomegroup-specific protein8e-1579
NC_005945:1008000:101890610189061019115210Bacillus anthracis str. Sterne, complete genomehypothetical protein8e-1579
NC_007530:1007140:101901310190131019177165Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein1e-1478.6
NC_004722:1008500:102081110208111020975165Bacillus cereus ATCC 14579, complete genomehypothetical protein1e-1478.6
NC_003997:1007139:101901310190131019177165Bacillus anthracis str. Ames, complete genomehypothetical protein1e-1478.6
NC_011773:1050000:106121810612181061382165Bacillus cereus AH820 chromosome, complete genomehypothetical protein1e-1478.6
NC_014171:1018338:103056210305621030726165Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein1e-1478.6
NC_016779:991298:100007510000751000239165Bacillus cereus F837/76 chromosome, complete genomehypothetical protein1e-1478.6
NC_017208:1050414:106359710635971063761165Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein1e-1478.6
NC_011772:1011220:102109110210911021255165Bacillus cereus G9842, complete genomehypothetical protein4e-1476.6
NC_017200:1157835:117204811720481172212165Bacillus thuringiensis serovar finitimus YBT-020 chromosome,group-specific protein5e-1476.3
NC_011725:1032500:104487010448701045025156Bacillus cereus B4264 chromosome, complete genomehypothetical protein4e-1373.6