Pre_GI: BLASTP Hits

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Query: NC_012659:1008028:1013238 Bacillus anthracis str. A0248, complete genome

Start: 1013238, End: 1013687, Length: 450

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007530:1007140:101333810133381013787450Bacillus anthracis str. 'Ames Ancestor', complete genomedna-binding protein7e-82301
NC_011773:1050000:105554110555411055990450Bacillus cereus AH820 chromosome, complete genomehypothetical protein1e-76284
NC_017208:1050414:105646110564611056910450Bacillus thuringiensis serovar chinensis CT-43 chromosome, completetranscriptional repressor2e-75280
NC_010184:1017000:102191410219141022363450Bacillus weihenstephanensis KBAB4, complete genometranscriptional regulator, XRE family2e-75280
NC_004722:1008500:101368010136801014129450Bacillus cereus ATCC 14579, complete genomeTranscriptional repressor2e-74277
NC_005957:1037205:104193210419321042381450Bacillus thuringiensis serovar konkukian str. 97-27, completepossible transcriptional regulator; possible DNA-binding protein4e-74276
NC_016779:991298:994401994401994850450Bacillus cereus F837/76 chromosome, complete genomeXRE family transcriptional regulator9e-74275
NC_011772:1011220:101541510154151015864450Bacillus cereus G9842, complete genomehypothetical protein2e-73273
NC_011725:1032500:103773410377341038183450Bacillus cereus B4264 chromosome, complete genomehypothetical protein2e-73273
NC_004193:2921103:293865229386522939191540Oceanobacillus iheyensis HTE831, complete genomehypothetical protein3e-51200
NC_019897:73957:123516123516123968453Thermobacillus composti KWC4 chromosome, complete genometranscriptional regulator1e-45181
NC_005945:1008000:101323210132321013510279Bacillus anthracis str. Sterne, complete genomeDNA-binding protein9e-45178
NC_007530:1007140:101357210135721013787216Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein3e-34144
NC_003997:1007139:101357210135721013787216Bacillus anthracis str. Ames, complete genomehypothetical protein3e-34144
NC_003997:1007139:101333710133371013558222Bacillus anthracis str. Ames, complete genomeDNA-binding protein2e-34144
NC_005945:1008000:101348010134801013680201Bacillus anthracis str. Sterne, complete genomehypothetical protein4e-29126
NC_011969:1084000:108843010884301088648219Bacillus cereus Q1 chromosome, complete genometranscriptional repressor1e-24112
NC_009328:3241166:324657732465773246852276Geobacillus thermodenitrificans NG80-2 chromosome, complete genomehypothetical protein6e-1889.4
NC_021184:3497000:350753735075373508112576Desulfotomaculum gibsoniae DSM 7213, complete genomeputative transcription factor, MBF1 like protein4e-1786.7
NC_014171:1018338:102372210237221023880159Bacillus thuringiensis BMB171 chromosome, complete genometranscriptional repressor5e-1786.7
NC_013165:1780321:179707517970751797665591Slackia heliotrinireducens DSM 20476, complete genomepredicted transcriptional regulator3e-1580.9
NC_007907:1996194:200522520052252006193969Desulfitobacterium hafniense Y51, complete genomehypothetical protein6e-1579.7
NC_011830:3081726:309011130901113091079969Desulfitobacterium hafniense DCB-2, complete genometranscriptional regulator, XRE family9e-1579
NC_016048:1930089:194775419477541948359606Oscillibacter valericigenes Sjm18-20, complete genomeputative Xre family DNA-binding protein5e-1476.6
NC_015738:220000:232818232818233381564Eggerthella sp. YY7918, complete genomehypothetical protein5e-1373.2
NC_013721:533048:557357557357558343987Gardnerella vaginalis 409-05, complete genomeDNA-binding protein2e-1271.2
NC_015732:982774:9996799996791000284606Spirochaeta caldaria DSM 7334 chromosome, complete genomehelix-turn-helix domain-containing protein5e-1270.1
NC_015977:2966971:298258929825892983200612Roseburia hominis A2-183 chromosome, complete genomehypothetical protein1e-1168.6
NC_018720:1336839:134774913477491348339591Bifidobacterium asteroides PRL2011 chromosome, complete genomeDNA-binding protein6e-1166.2
NC_010520:725312:730360730360730752393Clostridium botulinum A3 str. Loch Maree, complete genomeDNA-binding protein3e-1063.9
NC_008497:79144:963919639196705315Lactobacillus brevis ATCC 367, complete genomeTranscriptional regulator, xre family3e-1063.9
NC_012891:1277966:129143912914391292212774Streptococcus dysgalactiae subsp. equisimilis GGS_124 chromosome 1,hypothetical protein3e-1063.9
NC_015589:2878000:287984128798412880455615Desulfotomaculum ruminis DSM 2154 chromosome, complete genomehelix-turn-helix domain-containing protein4e-1063.5
NC_014334:2696000:271134127113412711898558Lactobacillus casei str. Zhang chromosome, complete genomeXRE family transcriptional regulator5e-1063.5
NC_010816:1274702:1286137128613712872251089Bifidobacterium longum DJO10A, complete genomeXre-type transcriptional regulator6e-1063.2
NC_012814:1092860:1094496109449610955031008Bifidobacterium animalis subsp. lactis Bl-04, complete genomeXre-type transcriptional regulator6e-1063.2
NC_012815:1092795:1094431109443110954381008Bifidobacterium animalis subsp. lactis DSM 10140, complete genomeXre-type transcriptional regulator6e-1063.2
NC_011835:1819707:1821343182134318223501008Bifidobacterium animalis subsp. lactis AD011 chromosome, completetranscriptional regulator6e-1063.2
NC_017216:1092751:1094387109438710953941008Bifidobacterium animalis subsp. lactis BLC1, complete genometranscriptional regulator6e-1063.2
NC_017217:1092916:1094552109455210955591008Bifidobacterium animalis subsp. lactis V9 chromosome, completeXre-type transcriptional regulator6e-1063.2
NC_009328:293000:362637362637363419783Geobacillus thermodenitrificans NG80-2 chromosome, complete genomehypothetical protein8e-1062.8
NC_003923:2794686:281261228126122813181570Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein8e-1062.8
NC_002953:2773000:279195227919522792521570Staphylococcus aureus subsp. aureus MSSA476, complete genomehypothetical protein8e-1062.8
NC_014479:509919:530075530075530860786Bacillus subtilis subsp. spizizenii str. W23 chromosome, completehelix-turn-helix domain-containing protein7e-1062.8
NC_017214:1727676:1729273172927317303191047Bifidobacterium animalis subsp. lactis BB-12 chromosome, completetranscriptional regulator6e-1062.8
NC_017215:1091941:1094155109415510952011047Bifidobacterium animalis subsp. lactis CNCM I-2494 chromosome,transcriptional regulator6e-1062.8
NC_018720:417500:4175284175284185561029Bifidobacterium asteroides PRL2011 chromosome, complete genometranscriptional regulator8e-1062.4
NC_015977:3011177:302804130280413028793753Roseburia hominis A2-183 chromosome, complete genomehypothetical protein1e-0962
NC_020995:1205524:122679012267901227404615Enterococcus casseliflavus EC20, complete genomehypothetical protein3e-0960.8
NC_010001:69000:909309093091751822Clostridium phytofermentans ISDg, complete genometranscriptional regulator, XRE family3e-0960.5
NC_021175:2063611:207187220718722072216345Streptococcus oligofermentans AS 1.3089, complete genomeCro/CI family transcriptional regulator4e-0960.5
NC_009012:1857845:1863582186358218647061125Clostridium thermocellum ATCC 27405, complete genometranscriptional regulator, XRE family4e-0960.1
NC_011884:2921618:292676229267622927436675Cyanothece sp. PCC 7425, complete genometranscriptional regulator, XRE family7e-0959.7
NC_015428:193817:204686204686204910225Lactobacillus buchneri NRRL B-30929 chromosome, complete genomehelix-turn-helix domain-containing protein2e-0858.5
NC_013895:117429:164188164188164820633Clostridiales genomosp. BVAB3 str. UPII9-5 chromosome, completeDNA-binding protein1e-0858.5
NC_013385:90331:106210106210106566357Ammonifex degensii KC4, complete genometranscriptional regulator, XRE family1e-0858.5
NC_013721:533048:555423555423556055633Gardnerella vaginalis 409-05, complete genomeDNA-binding protein2e-0858.2
NC_014644:1275038:127837012783701279002633Gardnerella vaginalis ATCC 14019 chromosome, complete genomeXRE family transcriptional regulator3e-0857.4
NC_012962:1068102:109723810972381097639402Photorhabdus asymbiotica, complete genomeputative phage regulator3e-0857.4
NC_012962:1068102:108946510894651089866402Photorhabdus asymbiotica, complete genomeputative phage regulator3e-0857.4
NC_015660:1076159:108793410879341088275342Geobacillus thermoglucosidasius C56-YS93 chromosome, completehelix-turn-helix domain-containing protein3e-0857.4
NC_009455:53000:939229392294554633Dehalococcoides sp. BAV1 chromosome, complete genomeXRE family transcriptional regulator4e-0857
NC_012781:2552723:257337025733702573741372Eubacterium rectale ATCC 33656, complete genomehypothetical protein3e-0857
NC_012781:700226:725018725018725389372Eubacterium rectale ATCC 33656, complete genomehypothetical protein3e-0857
NC_015573:2463123:248662424866242486842219Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomehelix-turn-helix domain-containing protein6e-0856.2
NC_014206:3355156:337460433746043375011408Geobacillus sp. C56-T3 chromosome, complete genomeXRE family transcriptional regulator6e-0856.2
NC_013411:3314799:335015933501593350566408Geobacillus sp. Y412MC61, complete genometranscriptional regulator, XRE family6e-0856.2
NC_014915:3320768:335612833561283356535408Geobacillus sp. Y412MC52 chromosome, complete genomehelix-turn-helix domain protein6e-0856.2
NC_014958:514225:515765515765516331567Deinococcus maricopensis DSM 21211 chromosome, complete genomehelix-turn-helix domain-containing protein1e-0755.8
NC_014759:4133809:415013541501354150905771Marivirga tractuosa DSM 4126 chromosome, complete genomehelix-turn-helix domain protein1e-0755.5
NC_020210:3246839:326198032619803262387408Geobacillus sp. GHH01, complete genometranscriptional regulator2e-0754.7
NC_015634:2492771:249595924959592496378420Bacillus coagulans 2-6 chromosome, complete genomeXRE family transcriptional regulator2e-0754.7
NC_016627:1960097:196316219631621963602441Clostridium clariflavum DSM 19732 chromosome, complete genomelooped-hinge helix DNA binding domain, AbrB family2e-0754.7
NC_009012:2927793:293408629340862934514429Clostridium thermocellum ATCC 27405, complete genometranscriptional regulator, XRE family2e-0754.3
NC_016048:751000:769269769269769643375Oscillibacter valericigenes Sjm18-20, complete genomeputative Xre family DNA-binding protein3e-0754.3
NC_016048:2167440:217717721771772177911735Oscillibacter valericigenes Sjm18-20, complete genomeputative Xre family DNA-binding protein3e-0754.3
NC_017025:1651870:166594816659481666286339Flavobacterium indicum GPTSA100-9, complete genometranscriptional regulator, XRE family3e-0753.9
NC_014963:767034:794076794076794264189Terriglobus saanensis SP1PR4 chromosome, complete genomeXRE family transcriptional regulator5e-0753.5
NC_011660:2924397:292631729263172926793477Listeria monocytogenes HCC23 chromosome, complete genomegp334e-0753.5
NC_010001:109893:129389129389129880492Clostridium phytofermentans ISDg, complete genometranscriptional regulator, XRE family4e-0753.5
NC_014650:603500:617995617995618441447Geobacillus sp. Y4.1MC1 chromosome, complete genomehelix-turn-helix domain-containing protein4e-0753.5
NC_000964:2146000:222025722202572220583327Bacillus subtilis subsp. subtilis str. 168, complete genomehypothetical protein6e-0753.1
NC_012778:403962:424154424154424807654Eubacterium eligens ATCC 27750, complete genomehypothetical protein1e-0652.4
NC_017068:2827568:284872528487252849108384Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative Xre family transcriptional regulator9e-0752.4
NC_006322:1415863:142614914261491426517369Bacillus licheniformis ATCC 14580, complete genomeYqaE9e-0752.4
NC_006270:1415001:142528614252861425654369Bacillus licheniformis ATCC 14580, complete genomeprobable transcriptional regulator (phage-related)9e-0752.4
NC_014538:2158131:218091821809182181331414Thermoanaerobacter sp. X513 chromosome, complete genomehelix-turn-helix domain-containing protein1e-0652
NC_013766:679906:683546683546683872327Listeria monocytogenes 08-5578 chromosome, complete genometranscriptional regulator1e-0652
NC_014136:329484:330462330462330773312Leuconostoc kimchii IMSNU11154 chromosome, complete genometranscription regulator1e-0652
NC_014551:576000:577723577723578103381Bacillus amyloliquefaciens DSM 7, complete genomehypothetical protein2e-0651.6
NC_015437:1494777:150426615042661504889624Selenomonas sputigena ATCC 35185 chromosome, complete genomehelix-turn-helix domain protein2e-0651.6
NC_014831:8965:183241832418545222Thermaerobacter marianensis DSM 12885 chromosome, complete genomehelix-turn-helix domain protein1e-0651.6
NC_014833:3161257:316420531642053164792588Ruminococcus albus 7 chromosome, complete genomehelix-turn-helix domain-containing protein1e-0651.6
NC_011837:3272752:329170232917023292304603Clostridium kluyveri NBRC 12016, complete genomehypothetical protein2e-0651.2
NC_009706:3341250:336020033602003360802603Clostridium kluyveri DSM 555 chromosome, complete genometranscriptional regulator2e-0651.2
NC_020995:3252500:325400432540043254495492Enterococcus casseliflavus EC20, complete genomehypothetical protein3e-0650.8
NC_009706:2003194:202021320202132020998786Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein2e-0650.8
NC_011837:1935294:195171619517161952501786Clostridium kluyveri NBRC 12016, complete genomehypothetical protein2e-0650.8
NC_016510:2312481:232574323257432326075333Flavobacterium columnare ATCC 49512 chromosome, complete genomehelix-turN-helix domain protein2e-0650.8
NC_014258:42262:668136681367391579Pantoea vagans C9-1 plasmid pPag3, complete sequenceputative HTH-type transcriptional regulatory protein4e-0650.4
NC_013132:5942981:595027859502785950613336Chitinophaga pinensis DSM 2588, complete genometranscriptional regulator, XRE family4e-0650.4
NC_000964:521975:530691530691531074384Bacillus subtilis subsp. subtilis str. 168, complete genomehypothetical protein4e-0650.4
NC_015420:35384:219421942349156Lactobacillus buchneri NRRL B-30929 plasmid pLBUC01, complete3e-0650.4
NC_014624:828943:829811829811830257447Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein3e-0650.4
NC_011830:1037520:105910110591011059934834Desulfitobacterium hafniense DCB-2, complete genometranscriptional regulator, XRE family5e-0650.1
NC_014964:2272413:229248922924892292878390Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completehelix-turn-helix domain-containing protein7e-0649.7
NC_009706:1972000:199149419914941992135642Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein7e-0649.3
NC_017068:1327025:134093213409321341534603Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative Xre family transcriptional regulator8e-0649.3
NC_012658:1658505:1670222167022216713341113Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative DNA-binding protein1e-0548.9