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Query: NC_012659:1008028:1008028 Bacillus anthracis str. A0248, complete genome

Start: 1008028, End: 1009005, Length: 978

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003997:1007139:100812710081271009104978Bacillus anthracis str. Ames, complete genomeglyoxylase family protein0662
NC_007530:1007140:100812810081281009105978Bacillus anthracis str. 'Ames Ancestor', complete genomeglyoxylase family protein0662
NC_005945:1008000:100802210080221008999978Bacillus anthracis str. Sterne, complete genomeglyoxylase family protein0662
NC_008600:1042477:104247710424771043469993Bacillus thuringiensis str. Al Hakam, complete genomeglyoxalase family protein0657
NC_017200:1157835:116015511601551161132978Bacillus thuringiensis serovar finitimus YBT-020 chromosome,glyoxalase family protein0649
NC_013526:439813:471690471690472664975Thermobaculum terrenum ATCC BAA-798 chromosome 2, complete genomeGlyoxalase/bleomycin resistance protein/dioxygenase3e-66252
NC_003997:1007139:100713910071391008083945Bacillus anthracis str. Ames, complete genomeglyoxalase family protein1e-59230
NC_007530:1007140:100714010071401008084945Bacillus anthracis str. 'Ames Ancestor', complete genomeglyoxalase family protein1e-59230
NC_017200:1157835:115916611591661160110945Bacillus thuringiensis serovar finitimus YBT-020 chromosome,glyoxalase family protein3e-58225
NC_014210:2638773:264167626416762642626951Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,Glyoxalase/bleomycin resistance protein/dioxygenase2e-53209
NC_009142:4046376:406659740665974067580984Saccharopolyspora erythraea NRRL 2338, complete genomeglyoxalase/bleomycin resistance protein/dioxygenase2e-51202
NC_006322:1959918:197037519703751971313939Bacillus licheniformis ATCC 14580, complete genomeYdfO4e-48192
UCMB5137:2418403:243028124302812431219939Bacillus atrophaeus UCMB-5137putative dioxygenase1e-47190
NC_006396:2025500:202607220260722027061990Haloarcula marismortui ATCC 43049 chromosome I, complete sequencedioxgenase1e-47190
NC_014639:2452286:246431024643102465248939Bacillus atrophaeus 1942 chromosome, complete genomedioxygenase3e-47188
CP002207:2452286:246431024643102465248939Bacillus atrophaeus 1942, complete genomeputative dioxygenase3e-47188
NC_014019:3543389:354715235471523548090939Bacillus megaterium QM B1551 chromosome, complete genomeGlyoxalase/Bleomycin resistance protein/Dioxygenase family protein1e-46187
NC_020164:89214:101792101792102730939Staphylococcus warneri SG1, complete genomeputative dioxygenase2e-46186
NC_009952:592000:636471636471637394924Dinoroseobacter shibae DFL 12, complete genomeglyoxalase/bleomycin resistance protein/dioxygenase1e-41170
NC_013202:1367447:137176813717681372700933Halomicrobium mukohataei DSM 12286, complete genomeGlyoxalase/bleomycin resistance protein/dioxygenase4e-40165
NC_020302:85821:136227136227137198972Corynebacterium halotolerans YIM 70093 = DSM 44683, completeGlyoxalase/bleomycin resistance protein/dioxygenase5e-24112
NC_011881:89705:104915104915105868954Arthrobacter chlorophenolicus A6 plasmid pACHL02, completeGlyoxalase/bleomycin resistance protein/dioxygenase3e-1996.3