Pre_GI: BLASTN Hits

Some Help

Query: NC_012658:99899 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 99899, End: 119374, Length: 19476

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_003030:3112931*3112931313070517775Clostridium acetobutylicum ATCC 824, complete genome3e-166593BLASTN svgBLASTP svg
NC_020291:79502*7950210385024349Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome2e-1695.6BLASTN svgBLASTP svg
NC_020291:795500*79550085457259073Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome2e-0971.9BLASTN svgBLASTP svg
NC_014410:403776*40377646022156446Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,6e-1073.8BLASTN svgBLASTP svg
NC_019970:439969*43996946091520947Thermoanaerobacterium thermosaccharolyticum M0795, complete genome6e-1073.8BLASTN svgBLASTP svg