Pre_GI: BLASTN Hits

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Query: NC_012658:2295536 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 2295536, End: 2319262, Length: 23727

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_012563:23845002384500240296118462Clostridium botulinum A2 str. Kyoto, complete genome04865BLASTN svgBLASTP svg
NC_004557:15530001553000157059917600Clostridium tetani E88, complete genome03126BLASTN svgBLASTP svg
NC_010674:14965001496500152566029161Clostridium botulinum B str. Eklund 17B, complete genome01865BLASTN svgBLASTP svg
NC_010723:14650971465097149459929503Clostridium botulinum E3 str. Alaska E43, complete genome01818BLASTN svgBLASTP svg
NC_014328:43160084316008434476228755Clostridium ljungdahlii ATCC 49587 chromosome, complete genome01011BLASTN svgBLASTP svg
NC_009922:25560332556033258448628454Alkaliphilus oremlandii OhILAs, complete genome0787BLASTN svgBLASTP svg
NC_010001:17450891745089177589430806Clostridium phytofermentans ISDg, complete genome8e-127462BLASTN svgBLASTP svg
NC_014328:12864071286407130824221836Clostridium ljungdahlii ATCC 49587 chromosome, complete genome7e-81309BLASTN svgBLASTP svg
NC_004557:2289135*2289135231328724153Clostridium tetani E88, complete genome8e-56226BLASTN svgBLASTP svg
NC_008261:10485151048515107289224378Clostridium perfringens ATCC 13124, complete genome3e-37165BLASTN svgBLASTP svg
NC_003366:10917661091766111615524390Clostridium perfringens str. 13, complete genome3e-37165BLASTN svgBLASTP svg
NC_014019:35433893543389356611222724Bacillus megaterium QM B1551 chromosome, complete genome5e-23117BLASTN svgBLASTP svg
NC_009922:86826286826289020421943Alkaliphilus oremlandii OhILAs, complete genome3e-21111BLASTN svgBLASTP svg
NC_018664:3009166*3009166304846639301Clostridium acidurici 9a chromosome, complete genome1e-20109BLASTN svgBLASTP svg
NC_015275:44935004493500451163218133Clostridium lentocellum DSM 5427 chromosome, complete genome5e-20107BLASTN svgBLASTP svg
NC_013192:63111631119378730677Leptotrichia buccalis DSM 1135, complete genome5e-1797.6BLASTN svgBLASTP svg
NC_010723:19671061967106199111924014Clostridium botulinum E3 str. Alaska E43, complete genome5e-1797.6BLASTN svgBLASTP svg
NC_014376:15866491586649160872922081Clostridium saccharolyticum WM1 chromosome, complete genome8e-1693.7BLASTN svgBLASTP svg
NC_013517:1055854*10558541161670105817Sebaldella termitidis ATCC 33386, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_010674:18229631822963184273319771Clostridium botulinum B str. Eklund 17B, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_014538:985339985339100713721799Thermoanaerobacter sp. X513 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_014614:284005*28400531809934095Clostridium sticklandii, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_014654:11131161113116113933826223Halanaerobium sp. 'sapolanicus' chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg