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Query: NC_012658:125500 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 125500, End: 147599, Length: 22100

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010516:127000*12700015115624157Clostridium botulinum B1 str. Okra, complete genome09065BLASTN svgBLASTP svg
NC_012563:122000*12200014417822179Clostridium botulinum A2 str. Kyoto, complete genome09010BLASTN svgBLASTP svg
NC_010520:121077*12107714384722771Clostridium botulinum A3 str. Loch Maree, complete genome08994BLASTN svgBLASTP svg
NC_014328:180482*18048220427623795Clostridium ljungdahlii ATCC 49587 chromosome, complete genome5e-137496BLASTN svgBLASTP svg
NC_008593:22508712250871226893418064Clostridium novyi NT, complete genome5e-20107BLASTN svgBLASTP svg
NC_019978:31534631534633383318488Halobacteroides halobius DSM 5150, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_021182:30041530041531873118317Clostridium pasteurianum BC1, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_008261:27439422743942276681822877Clostridium perfringens ATCC 13124, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_010674:37062937062939810727479Clostridium botulinum B str. Eklund 17B, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_016012:236012*23601227777541764Candidatus Arthromitus sp. SFB-rat-Yit, complete genome7e-0763.9BLASTN svgBLASTP svg