Pre_GI: BLASTP Hits

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Query: NC_012658:545840:563574 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 563574, End: 567104, Length: 3531

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010516:583870:5876355876355911653531Clostridium botulinum B1 str. Okra, complete genomeexonuclease SbcC01743
NC_009699:564455:5709295709295744593531Clostridium botulinum F str. Langeland chromosome, complete genomeexonuclease SbcC01732
NC_017297:564727:5712015712015727811581Clostridium botulinum F str. 230613 chromosome, complete genome0853
NC_015425:405058:4139804139804175103531Clostridium botulinum BKT015925 chromosome, complete genomeexonuclease1e-86322
NC_009617:1165539:1172409117240911759003492Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeSMC domain-containing protein2e-68261
NC_014328:2203437:2207647220764722111413495Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative nuclease sbcCD subunit C7e-66253
NC_008261:225425:2528992528992564173519Clostridium perfringens ATCC 13124, complete genomeexonuclease SbcC1e-57226
NC_008262:227354:2553562553562588743519Clostridium perfringens SM101, complete genomeexonuclease SbcC1e-57225
NC_003366:255480:2835142835142870413528Clostridium perfringens str. 13, complete genomeprobable exonuclease3e-57224
NC_014622:3819495:3822728382272838261173390Paenibacillus polymyxa SC2 chromosome, complete genomesmc domain protein5e-48194
NC_016641:5528826:5535086553508655384843399Paenibacillus terrae HPL-003 chromosome, complete genomeDNA repair ATPase3e-48194
NC_014483:3498395:3502055350205535054503396Paenibacillus polymyxa E681 chromosome, complete genomeATPase involved in DNA repair3e-48194
NC_014633:339181:3420573420573450743018Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequenceSMC domain-containing protein1e-47192
NC_013730:7118798:7136893713689371399823090Spirosoma linguale DSM 74, complete genomeATPase-like protein involved in DNA repair2e-26122
NC_019904:2010999:2007979200797920110023024Echinicola vietnamensis DSM 17526 chromosome, complete genomeDNA repair ATPase9e-26120
NC_014966:638355:6383556383556414203066Vibrio vulnificus MO6-24/O chromosome II, complete sequenceexonuclease SbcC1e-22109
NC_005140:660305:6603056603056633703066Vibrio vulnificus YJ016 chromosome II, complete sequenceputative exonuclease SbcC2e-22109
NC_004460:81687:8168781687847523066Vibrio vulnificus CMCP6 chromosome II, complete sequenceATPase involved in DNA repair2e-22108
NC_016630:1610723:1607605160760516107363132Filifactor alocis ATCC 35896 chromosome, complete genomeexonuclease SbcC4e-22107
NC_015510:8069440:8088951808895180925983648Haliscomenobacter hydrossis DSM 1100 chromosome, complete genomeSMC domain-containing protein1e-21106
NC_017955:4746441:4746441474644147487652325Modestobacter marinus, complete genomehypothetical protein2e-20102
NC_008740:637870:6514396514396547143276Marinobacter aquaeolei VT8, complete genomeSMC domain protein1e-1999.8
NC_007484:755058:7563267563267596013276Nitrosococcus oceani ATCC 19707, complete genomeATP-dependent dsDNA exonuclease (SbcC)1e-1999.8
NC_013715:767722:7862597862597895523294Rothia mucilaginosa DY-18, complete genomeATPase involved in DNA repair1e-1999.4
NC_013520:1559000:1577803157780315808863084Veillonella parvula DSM 2008, complete genomeATPase involved in DNA repair-like protein2e-1999.4
NC_011658:2275864:2293805229380522968943090Bacillus cereus AH187 chromosome, complete genomeputative exonuclease4e-1998.2
NC_017328:335160:3599823599823631253144Shigella flexneri 2002017 chromosome, complete genomeATP-dependent dsDNA exonuclease3e-1998.2
NC_012472:2240000:2258080225808022611693090Bacillus cereus 03BB102, complete genomeputative exonuclease1e-1896.7
NC_011773:2239753:2258273225827322613623090Bacillus cereus AH820 chromosome, complete genomeputative exonuclease1e-1896.7
NC_003997:2175843:2194319219431921974083090Bacillus anthracis str. Ames, complete genomeexonuclease, putative1e-1896.7
NC_014335:2151404:2170610217061021736993090Bacillus cereus biovar anthracis str. CI chromosome, completeexonuclease SbcC1e-1896.7
NC_005945:2175871:2194425219442521975143090Bacillus anthracis str. Sterne, complete genomeexonuclease, putative1e-1896.7
NC_007530:2175967:2194443219444321975323090Bacillus anthracis str. 'Ames Ancestor', complete genomeexonuclease, putative1e-1896.7
NC_012659:2175867:2194343219434321974323090Bacillus anthracis str. A0248, complete genomeputative exonuclease1e-1896.7
NC_005957:2196000:2213974221397422170633090Bacillus thuringiensis serovar konkukian str. 97-27, completeexonuclease SbcC1e-1896.3
NC_011725:2206000:2224750222475022278393090Bacillus cereus B4264 chromosome, complete genomeexonuclease2e-1895.5
NC_014171:2177353:2196894219689421999833090Bacillus thuringiensis BMB171 chromosome, complete genomeexonuclease SbcC2e-1895.5
NC_011772:2166000:2184317218431721874063090Bacillus cereus G9842, complete genomeputative exonuclease4e-1894.7
NC_015578:3561838:3580249358024935834313183Treponema primitia ZAS-2 chromosome, complete genomenuclease sbcCD subunit C5e-1894.4
NC_016830:4295831:4297092429709243007333642Pseudomonas fluorescens F113 chromosome, complete genomeprotein SbcC6e-1894
NC_015975:441580:4427044427044458083105Lactobacillus ruminis ATCC 27782 chromosome, complete genomeExonuclease SbcCD subunit C2e-1792.4
NC_014972:3688000:3712226371222637158883663Desulfobulbus propionicus DSM 2032 chromosome, complete genomeSMC domain-containing protein2e-1792.4
NC_015500:2112975:2146324214632421494163093Treponema brennaborense DSM 12168 chromosome, complete genomeexonuclease3e-1791.7
NC_016002:1975000:1976360197636019797823423Pseudogulbenkiania sp. NH8B, complete genomenuclease SbcCD subunit C3e-1791.7
NC_015497:1058980:1066367106636710700533687Glaciecola agarilytica 4H-3-7+YE-5 chromosome, complete genomeSMC domain protein5e-1790.9
NC_016745:123772:1392501392501426603411Oceanimonas sp. GK1 chromosome, complete genomeSMC domain-containing protein9e-1790.1
NC_016111:409852:4307414307414337493009Streptomyces cattleya NRRL 8057, complete genomeATP-dependent dsDNA exonuclease3e-1688.2
NC_015733:1793399:1793399179339917970433645Pseudomonas putida S16 chromosome, complete genomeSMC domain-containing protein4e-1688.2
NC_015437:767572:7702657702657733393075Selenomonas sputigena ATCC 35185 chromosome, complete genomeSMC domain protein6e-1687.4
NC_015930:821342:8269308269308300673138Lactococcus garvieae ATCC 49156, complete genomeexonuclease SbcC8e-1687
NC_009615:2039964:2044986204498620479672982Parabacteroides distasonis ATCC 8503 chromosome, complete genomeATP-dependent exonuclease sbcC1e-1586.3
NC_020054:2033982:2036050203605020391333084Fibrella aestuarina BUZ 2 drat genomeNuclease sbcCD subunit C2e-1585.5
NC_021171:1661923:1670095167009516732323138Bacillus sp. 1NLA3E, complete genomeSbcC family exonuclease2e-1585.5
NC_016776:3485688:3494865349486534978282964Bacteroides fragilis 638R, complete genomeputative exonuclease4e-1584.7
NC_014554:1339566:1347871134787113510563186Lactobacillus plantarum subsp. plantarum ST-III chromosome,exonuclease SbcC4e-1584.7
NC_003228:3455405:3463154346315434661172964Bacteroides fragilis NCTC 9343, complete genomeputative exonuclease4e-1584.7
NC_010612:4400260:4417219441721944202273009Mycobacterium marinum M, complete genomechromosome partition ATPase protein1e-1483.2
NC_015276:2552484:2552484255248425562843801Marinomonas mediterranea MMB-1 chromosome, complete genomeSMC domain protein1e-1483.2
NC_017955:4746441:4748762474876247501591398Modestobacter marinus, complete genomehypothetical protein3e-1482
NC_015172:1255956:1260972126097212641393168Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeSMC domain-containing protein3e-1482
NC_009663:738846:7433417433417457072367Sulfurovum sp. NBC37-1, complete genomeDNA double-strand break repair protein2e-1172
NC_004463:2059500:2075389207538920778392451Bradyrhizobium japonicum USDA 110, complete genomeexonuclease subunit SbcC homolog1e-1070.1
NC_013855:558831:5597075597075634683762Azospirillum sp. B510 plasmid pAB510a, complete sequenceexonuclease1e-1069.7
NC_017187:1564403:1580988158098815833572370Arcobacter butzleri ED-1, complete genomechromosome segregation protein2e-1068.9
NC_017187:1580988:1580988158098815833572370Arcobacter butzleri ED-1, complete genomechromosome segregation protein2e-1068.9
NC_015636:1603664:1611552161155216145452994Methanothermococcus okinawensis IH1 chromosome, complete genomeDNA double-strand break repair rad50 ATPase2e-0965.9
NC_014160:748743:7794917794917823042814Thermosphaera aggregans DSM 11486 chromosome, complete genomeSMC domain-containing protein3e-0965.5
NC_015416:2723189:2734177273417727373563180Methanosaeta concilii GP-6 chromosome, complete genomehypothetical protein1e-0863.5
NC_015931:1443447:1449031144903114517572727Pyrolobus fumarii 1A, complete genomeSMC domain containing protein1e-0863.2
NC_006396:1626472:1642111164211116448372727Haloarcula marismortui ATCC 43049 chromosome I, complete sequencechromosome segregation protein2e-0862.4
NC_014762:1204584:1218433121843312207902358Sulfuricurvum kujiense DSM 16994 chromosome, complete genomesmc domain protein3e-0758.2
UCMB5137:1159520:1166256116625611698163561Bacillus atrophaeus UCMB-5137chromosome segregation SMC protein4e-0757.8
NC_015666:252740:2539512539512571273177Halopiger xanaduensis SH-6 chromosome, complete genomeSMC domain-containing protein9e-0757
NC_014964:1309845:1310797131079713143873591Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completechromosome segregation protein SMC2e-0655.8
NC_014961:335808:3394023394023418822481Desulfurococcus mucosus DSM 2162 chromosome, complete genomeSMC domain-containing protein3e-0655.5
NC_014314:755166:7738247738247764152592Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completeSMC domain-containing protein4e-0654.7
NC_004193:1558551:1571140157114015747063567Oceanobacillus iheyensis HTE831, complete genomechromosome segregation SMC protein5e-0654.3
NC_015958:1422319:1422319142231914259093591Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomechromosome segregation protein SMC7e-0653.9
NC_014103:4059905:4059905405990540634653561Bacillus megaterium DSM319 chromosome, complete genomechromosome segregation protein SMC9e-0653.5