Pre_GI: BLASTP Hits

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Query: NC_012658:545840:555371 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 555371, End: 555940, Length: 570

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015555:863173:884649884649885218570Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeLemA family protein4e-52204
NC_015275:882022:894719894719895288570Clostridium lentocellum DSM 5427 chromosome, complete genomeLemA family protein4e-52203
NC_017095:2058921:206405320640532064622570Fervidobacterium pennivorans DSM 9078 chromosome, complete genomehypothetical protein5e-50197
NC_000853:960248:978331978331978912582Thermotoga maritima MSB8, complete genomelemA protein6e-49193
NC_011978:1581994:158440715844071584988582Thermotoga neapolitana DSM 4359, complete genomeLemA family protein precursor6e-49193
NC_011830:923424:965229965229965786558Desulfitobacterium hafniense DCB-2, complete genomeLemA family protein5e-46183
NC_007907:5056036:505603650560365056611576Desulfitobacterium hafniense Y51, complete genomehypothetical protein1e-45182
NC_014759:2598515:260339526033952603991597Marivirga tractuosa DSM 4126 chromosome, complete genomelema family protein7e-43173
NC_014614:260782:263290263290263865576Clostridium sticklandii, complete genomeLemA protein9e-41166
NC_012108:4907430:492205549220554922645591Desulfobacterium autotrophicum HRM2, complete genomelemA family protein1e-39162
NC_009515:1409912:145059214505921451155564Methanobrevibacter smithii ATCC 35061, complete genomeLemA protein8e-39159
NC_007517:1515493:153308515330851533669585Geobacter metallireducens GS-15, complete genomeLemA2e-38158
NC_013132:1652477:167402416740241674614591Chitinophaga pinensis DSM 2588, complete genomeLemA family protein2e-38158
NC_007498:2638671:265724026572402657824585Pelobacter carbinolicus DSM 2380, complete genomehypothetical protein2e-37155
NC_010376:606000:623288623288623842555Finegoldia magna ATCC 29328, complete genomecytoplasmic membrane protein1e-36152
NC_014314:1148000:115113411511341151700567Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completeLemA family protein6e-36150
NC_002939:1601706:161766616176661618250585Geobacter sulfurreducens PCA, complete genomeLemA family protein8e-36149
NC_011297:767333:767333767333767884552Dictyoglomus thermophilum H-6-12, complete genomeLemA protein2e-35148
NC_011661:938754:938754938754939305552Dictyoglomus turgidum DSM 6724, complete genomeLemA family protein6e-35146
NC_007925:1448726:145105914510591451691633Rhodopseudomonas palustris BisB18, complete genomeLemA6e-34143
NC_016002:1938749:195654119565411957173633Pseudogulbenkiania sp. NH8B, complete genomeLemA family protein8e-34143
NC_010552:293703:314035314035314697663Burkholderia ambifaria MC40-6 chromosome 2, complete sequenceLemA family protein7e-33140
NC_016589:2824164:284707928470792847741663Burkholderia sp. YI23 chromosome 1, complete sequenceLemA family protein5e-33140
NC_014614:356746:366485366485367042558Clostridium sticklandii, complete genomehypothetical protein5e-33140
NC_007677:117625:134106134106134714609Salinibacter ruber DSM 13855, complete genomelemA protein3e-32137
NC_015433:1315363:133247913324791333060582Streptococcus suis ST3 chromosome, complete genomeLemA family protein3e-32137
NC_010682:1763769:178850917885091789132624Ralstonia pickettii 12J chromosome 1, complete sequenceLemA family protein5e-32137
NC_008260:2142311:215739721573972158044648Alcanivorax borkumensis SK2, complete genomeLemA family protein1e-31135
NC_020418:14965:184891848919085597Morganella morganii subsp. morganii KT, complete genomeLemA family protein3e-29127
NC_007164:1839154:184152118415211842081561Corynebacterium jeikeium K411, complete genomeputative LemA family protein1e-28125
NC_008782:2857899:285729128572912857902612Acidovorax sp. JS42, complete genomeLemA family protein6e-28123
NC_015422:3493396:350878135087813509395615Alicycliphilus denitrificans K601 chromosome, complete genomeLemA family protein9e-28123
NC_015422:2858228:285913528591352859746612Alicycliphilus denitrificans K601 chromosome, complete genomeLemA family protein3e-27121
NC_010554:2872000:288788628878862888482597Proteus mirabilis HI4320, complete genomehypothetical protein2e-25115
NC_009802:1827138:184614418461441846707564Campylobacter concisus 13826, complete genomeLemA protein2e-23108
NC_010159:409500:410628410628411170543Yersinia pestis Angola, complete genomeLemA family protein1e-22105
NC_007948:4646344:468925646892564689849594Polaromonas sp. JS666, complete genomeLemA2e-2098.6
NC_013446:4281250:430179143017914302378588Comamonas testosteroni CNB-2, complete genomeLemA5e-1994
NC_007907:2249607:225453922545392255093555Desulfitobacterium hafniense Y51, complete genomehypothetical protein8e-1993.2
NC_004663:4729452:472945247294524730012561Bacteroides thetaiotaomicron VPI-5482, complete genomehypothetical protein8e-1993.2
NC_005071:265520:285477285477285986510Prochlorococcus marinus str. MIT 9313, complete genomeputative lemA protein2e-1891.7
NC_008576:2868986:287634828763482877274927Magnetococcus sp. MC-1, complete genomeLemA family protein1e-1789.7
NC_007626:1038214:106736410673641068182819Magnetospirillum magneticum AMB-1, complete genomehypothetical protein2e-1789
NC_009092:4337617:435281043528104353379570Shewanella loihica PV-4, complete genomeLemA family protein7e-1787
NC_020134:1783000:180127918012791801584306Clostridium stercorarium subsp. stercorarium DSM 8532, completehypothetical protein1e-1685.9
NC_013169:2581500:259564925956492596242594Kytococcus sedentarius DSM 20547, complete genomehypothetical protein2e-1478.6
NC_015416:1679188:170606317060631706683621Methanosaeta concilii GP-6 chromosome, complete genomeLemA family protein1e-1376.3