Pre_GI: BLASTP Hits

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Query: NC_012658:3778822:3786021 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 3786021, End: 3786302, Length: 282

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009495:3688138:369533736953373695627291Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein6e-41165
NC_017297:3787191:379673037967303797011282Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein7e-41165
NC_009699:3790917:379811637981163798397282Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein7e-41165
NC_009698:3553365:356843535684353568716282Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein7e-41165
NC_009697:3659834:367132636713263671607282Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein7e-41165
NC_010516:3759136:376633537663353766616282Clostridium botulinum B1 str. Okra, complete genomehypothetical protein7e-41165
NC_012563:3956500:396324639632463963527282Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein7e-41165
NC_010520:3788702:379590137959013796182282Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein2e-40163
NC_021182:4557608:456430145643014564579279Clostridium pasteurianum BC1, complete genomehypothetical protein1e-1478.6
NC_017295:3250451:325705932570593257337279Clostridium acetobutylicum EA 2018 chromosome, complete genomeRibosomal protein L14E (archaeal/eukaryotic type)3e-1477
NC_015687:3252233:325942932594293259707279Clostridium acetobutylicum DSM 1731 chromosome, complete genome50S ribosomal protein L14E (/ type)3e-1477
NC_003030:3251941:325780232578023258080279Clostridium acetobutylicum ATCC 824, complete genomeRibosomal protein L14E (archaeal/eukaryotic type)3e-1477
NC_020134:2801199:281079028107902811080291Clostridium stercorarium subsp. stercorarium DSM 8532, completehypothetical protein3e-1063.9
NC_014393:4482896:449017044901704490448279Clostridium cellulovorans 743B chromosome, complete genome50S ribosomal protein L14E (/type)3e-1063.5
NC_014220:2239594:224883222488322249134303Syntrophothermus lipocalidus DSM 12680 chromosome, complete genomehypothetical protein2e-0961.2
NC_013921:1977444:199985019998502000116267Thermoanaerobacter italicus Ab9 chromosome, complete genomehypothetical protein2e-0857.8
NC_018664:2357882:236306223630622363334273Clostridium acidurici 9a chromosome, complete genomehypothetical protein4e-0857
NC_014209:1910109:193252319325231932789267Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,hypothetical protein8e-0855.8
NC_010321:429720:430482430482430748267Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completehypothetical protein5e-0753.1
NC_014964:388458:425898425898426164267Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completehypothetical protein5e-0753.1
NC_015958:2251619:228302522830252283291267Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomehypothetical protein7e-0752.8
NC_013385:1504650:150549415054941505781288Ammonifex degensii KC4, complete genomehypothetical protein7e-0752.8
NC_014720:1140765:115645811564581156727270Caldicellulosiruptor kronotskyensis 2002 chromosome, completehypothetical protein1e-0652
NC_009633:4563877:456590945659094566193285Alkaliphilus metalliredigens QYMF chromosome, complete genomehypothetical protein1e-0652
NC_014652:1032711:104909210490921049361270Caldicellulosiruptor hydrothermalis 108 chromosome, completehypothetical protein2e-0651.6
NC_014657:1540500:154402815440281544297270Caldicellulosiruptor owensensis OL chromosome, complete genomehypothetical protein2e-0651.6
NC_012034:1783912:180908018090801809349270Anaerocellum thermophilum DSM 6725, complete genomehypothetical protein2e-0651.6
NC_009437:2367842:239360223936022393871270Caldicellulosiruptor saccharolyticus DSM 8903, complete genomehypothetical protein2e-0651.6
NC_014721:1777644:180280918028091803078270Caldicellulosiruptor kristjanssonii 177R1B chromosome, completehypothetical protein2e-0651.6
NC_015949:1180755:120579712057971206066270Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomehypothetical protein2e-0651.6
NC_014392:969498:985185985185985454270Caldicellulosiruptor obsidiansis OB47 chromosome, complete genomehypothetical protein2e-0651.6
NC_008262:2598920:260525226052522605560309Clostridium perfringens SM101, complete genomehypothetical protein1e-0651.6
NC_008261:2957354:296286429628642963172309Clostridium perfringens ATCC 13124, complete genomehypothetical protein2e-0651.2
NC_003366:2731995:274021927402192740527309Clostridium perfringens str. 13, complete genomehypothetical protein5e-0649.7
NC_014624:3741764:374778437477843748086303Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein7e-0649.3