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Query: NC_012658:35500:77512 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 77512, End: 78453, Length: 942

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010520:35845:773957739578336942Clostridium botulinum A3 str. Loch Maree, complete genometransporter, CorA metal ion transporter family1e-161569
NC_017297:33519:785717857179512942Clostridium botulinum F str. 230613 chromosome, complete genometransporter, CorA metal ion transporter family5e-161566
NC_009699:33452:783037830379244942Clostridium botulinum F str. Langeland chromosome, complete genomeCorA family protein5e-161566
NC_009698:38000:764137641377354942Clostridium botulinum A str. Hall chromosome, complete genomeCorA family protein5e-161566
NC_009697:38000:764127641277353942Clostridium botulinum A str. ATCC 19397 chromosome, completeCorA family protein5e-161566
NC_009495:38000:836098360984550942Clostridium botulinum A str. ATCC 3502 chromosome, complete genometransporter CorA metal ion transporter family5e-161566
NC_010516:42475:832668326684207942Clostridium botulinum B1 str. Okra, complete genometransporter, CorA metal ion transporter family5e-161566
NC_012563:36000:775347753478475942Clostridium botulinum A2 str. Kyoto, complete genometransporter, CorA metal ion transporter family5e-161566
NC_009706:3845039:384698238469823847923942Clostridium kluyveri DSM 555 chromosome, complete genometransporter protein2e-123441
NC_011837:3776541:377848437784843779425942Clostridium kluyveri NBRC 12016, complete genomehypothetical protein2e-123441
NC_014328:85290:138868138868139809942Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative Mg2+ transporter protein5e-123440
NC_003030:303812:350221350221351168948Clostridium acetobutylicum ATCC 824, complete genomeMagnesium and cobalt transporter2e-114412
NC_015687:303810:350217350217351164948Clostridium acetobutylicum DSM 1731 chromosome, complete genomemagnesium/cobalt transporter CorA2e-114412
NC_008261:3014373:302553330255333026477945Clostridium perfringens ATCC 13124, complete genomeputative cation transporter2e-114412
NC_003366:2788268:280289328028932803837945Clostridium perfringens str. 13, complete genomeprobable transport protein2e-114412
NC_008593:2457594:245759424575942458544951Clostridium novyi NT, complete genomemagnesium transporter, CorA family1e-114412
NC_008262:2649289:266734826673482668292945Clostridium perfringens SM101, complete genomemagnesium and cobalt transporter4e-114410
NC_015425:2690448:269245826924582693408951Clostridium botulinum BKT015925 chromosome, complete genomeMg2+ transporter protein, CorA family protein3e-113408
NC_010723:173280:207806207806208753948Clostridium botulinum E3 str. Alaska E43, complete genomemagnesium and cobalt transporter3e-112405
NC_010674:192951:205989205989206936948Clostridium botulinum B str. Eklund 17B, complete genomemagnesium and cobalt transporter3e-112404
NC_016894:377446:386766386766387695930Acetobacterium woodii DSM 1030 chromosome, complete genomemagnesium and cobalt transporter CorA13e-81301
NC_015275:3976631:399481339948133995748936Clostridium lentocellum DSM 5427 chromosome, complete genomeMg2 transporter protein CorA family protein5e-81301
NC_015052:1313311:131725813172581318208951Bifidobacterium longum subsp. infantis 157F, complete genomemagnesium and cobalt transport protein1e-71270
NC_013520:1905554:192383319238331924786954Veillonella parvula DSM 2008, complete genomeMg2 transporter protein CorA family protein3e-65248
NC_012781:379200:380997380997381938942Eubacterium rectale ATCC 33656, complete genomeMg2+ and Co2+ transporter2e-61236
NC_017068:1852708:185979318597931860746954Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative magnesium and cobalt transporter2e-61236
NC_014960:1697818:172126917212691722201933Anaerolinea thermophila UNI-1, complete genomemagnesium transporter protein3e-58225
NC_015164:2305415:230541523054152306341927Bacteroides salanitronis DSM 18170 chromosome, complete genomeMg2 transporter protein CorA family protein2e-41170
NC_016940:190986:211009211009211956948Saprospira grandis str. Lewin chromosome, complete genomeMg2 transporter protein CorA family protein6e-39161
NC_008527:611836:630539630539631420882Lactococcus lactis subsp. cremoris SK11, complete genomeMg2+ and Co2+ transporter3e-1892.8
NC_014122:143446:143446143446144390945Methanocaldococcus infernus ME chromosome, complete genomemagnesium and cobalt transport protein CorA6e-1891.7
NC_010999:2059738:206699420669942067902909Lactobacillus casei, complete genomeMagnesium transporter (Magnesium transporter CorA)5e-1685.1
NC_000909:963984:965086965086966039954Methanocaldococcus jannaschii DSM 2661, complete genomemagnesium and cobalt transport protein (corA)3e-1582.4
NC_013887:1601730:160281616028161603769954Methanocaldococcus sp. FS406-22 chromosome, complete genomemagnesium and cobalt transport protein CorA6e-1581.6
NC_013156:1182609:118260911826091183562954Methanocaldococcus fervens AG86, complete genomemagnesium and cobalt transport protein CorA2e-1479.7
NC_007492:2994036:299681429968142997737924Pseudomonas fluorescens PfO-1, complete genomeMg2+ transporter protein, CorA-like3e-0963.2
NC_015379:2751342:276124927612492762199951Pseudomonas brassicacearum subsp. brassicacearum NFM421 chromosome,putative cation transporter, membrane protein7e-0961.6
NC_008255:4208913:4229484422948442305601077Cytophaga hutchinsonii ATCC 33406, complete genomemagnesium and cobalt transport protein7e-0651.6