Pre_GI: BLASTP Hits

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Query: NC_012658:3387774:3406942 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 3406942, End: 3408018, Length: 1077

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_020210:2133996:2158824215882421599301107Geobacillus sp. GHH01, complete genomehypothetical protein3e-103375
NC_014976:1:3160316042661107Bacillus subtilis BSn5 chromosome, complete genomeglycosyl transferase, group 2 family protein2e-88326
NC_014479:2038348:2053059205305920541651107Bacillus subtilis subsp. spizizenii str. W23 chromosome, completeglycosyl transferase, group 2 family protein9e-87320
NC_009089:3889811:3914368391436839154441077Clostridium difficile 630, complete genomeputative glycosyl transferase2e-82306
NC_009633:3457185:3473347347334734744321086Alkaliphilus metalliredigens QYMF chromosome, complete genomeglycosyl transferase family protein3e-81302
NC_010001:3421710:3429863342986334309331071Clostridium phytofermentans ISDg, complete genomeglycosyl transferase family 25e-80298
NC_012563:3556763:357050335705033570961459Clostridium botulinum A2 str. Kyoto, complete genomeglycosyl transferase, group 2 family3e-51202
NC_010516:3368951:338887433888743389305432Clostridium botulinum B1 str. Okra, complete genomeglycosyl transferase, group 2 family protein3e-46186
NC_010001:3421710:3430994343099434335582565Clostridium phytofermentans ISDg, complete genomeglycosyl transferase group 14e-38159
NC_015977:2966971:2988081298808129891511071Roseburia hominis A2-183 chromosome, complete genomeglycosyltransferase family 2 candidate b-glycosyltransferase3e-34145
NC_012563:3090954:3090954309095430923751422Clostridium botulinum A2 str. Kyoto, complete genomeglycosyl transferase, group 2 family2e-25117
NC_009495:2876865:2876865287686528782861422Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeglycosyl transferase family protein2e-25117
NC_009697:2790277:2790277279027727916981422Clostridium botulinum A str. ATCC 19397 chromosome, completeglycosyl transferase family protein2e-25117
NC_009698:2727203:2727203272720327286241422Clostridium botulinum A str. Hall chromosome, complete genomeglycosyl transferase family protein2e-25117
NC_007759:1356439:1385199138519913883573159Syntrophus aciditrophicus SB, complete genomeglycosyltransferase1e-22107
NC_007503:861668:8705448705448716381095Carboxydothermus hydrogenoformans Z-2901, complete genomeglycosyl transferase, group 2 family1e-21104
NC_017068:2569609:2590257259025725930912835Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative glycosyl transferase family 2 protein1e-21104
NC_013406:6568273:6576102657610265780271926Paenibacillus sp. Y412MC10 chromosome, complete genomefamily 2 glycosyl transferase2e-21103
NC_017095:1927118:1928880192888019315162637Fervidobacterium pennivorans DSM 9078 chromosome, complete genomeglycosyl transferase family protein1e-20101
NC_017068:2569609:2583823258382325874253603Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative glycosyl transferase family 2 protein2e-20100
NC_015977:189101:2069822069822081241143Roseburia hominis A2-183 chromosome, complete genomeglycosyltransferase2e-1996.7
NC_015687:3470829:3477719347771934795001782Clostridium acetobutylicum DSM 1731 chromosome, complete genomeTPR repeat-containing glycosyl transferase4e-1995.9
NC_003030:3465352:3476093347609334778741782Clostridium acetobutylicum ATCC 824, complete genomeGlycosyltransferase fused to TPR-repeat domain4e-1995.9
NC_017295:3472797:3475541347554134773221782Clostridium acetobutylicum EA 2018 chromosome, complete genomeGlycosyltransferase fused to TPR-repeat domain protein4e-1995.9
NC_003212:721112:7211127211127230251914Listeria innocua Clip11262, complete genomehypothetical protein2e-1893.6
NC_003210:721824:7218247218247237371914Listeria monocytogenes EGD-e, complete genomehypothetical protein2e-1893.6
NC_002973:730942:7363167363167382291914Listeria monocytogenes str. 4b F2365, complete genomeglycosyl transferase, group 2 family protein2e-1893.6
NC_013768:721897:7260517260517279641914Listeria monocytogenes 08-5923, complete genomehypothetical protein2e-1893.6
NC_013766:757987:7593477593477612601914Listeria monocytogenes 08-5578 chromosome, complete genomehypothetical protein2e-1893.6
NC_010723:801215:8125898125898144931905Clostridium botulinum E3 str. Alaska E43, complete genomeglycosyl transferase, family 24e-1892.4
NC_011884:732000:7530517530517542261176Cyanothece sp. PCC 7425, complete genomeglycosyl transferase family 26e-1892
NC_015172:2628128:267380726738072674226420Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeglycosyl transferase family 28e-1891.7
NC_012914:6583000:6598394659839466002411848Paenibacillus sp. JDR-2, complete genomeglycosyl transferase family 22e-1790.1
NC_013205:2610956:2640858264085826431222265Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446,glycosyl transferase family 25e-1789
NC_014376:3732547:3746784374678437481001317Clostridium saccharolyticum WM1 chromosome, complete genomeglycosyl transferase family 27e-1788.2
NC_014828:107802:1272731272731290901818Ethanoligenens harbinense YUAN-3 chromosome, complete genomeglycosyl transferase family 21e-1687.8
NC_013642:545464:5558675558675584492583Thermotoga naphthophila RKU-10, complete genomeglycosyl transferase family 22e-1687
NC_011653:1339868:1376499137649913790902592Thermosipho africanus TCF52B, complete genomeglycosyl transferase, group 2 family protein3e-1686.3
NC_014377:1546124:1565388156538815684143027Thermosediminibacter oceani DSM 16646 chromosome, complete genomeglycosyl transferase family 24e-1685.9
NC_014500:1862000:1911729191172919127901062Dickeya dadantii 3937 chromosome, complete genomeglycosyl transferase, group 2 family protein6e-1685.1
NC_010674:828191:8354108354108373141905Clostridium botulinum B str. Eklund 17B, complete genomeglycosyl transferase, family 21e-1584.7
NC_008609:3672653:3675024367502436788303807Pelobacter propionicus DSM 2379, complete genomeglycosyl transferase, family 21e-1584.3
NC_004113:350059:3662873662873673841098Thermosynechococcus elongatus BP-1, complete genomeputative glycosyltransferase2e-1584
NC_010814:3621215:3621215362121536255224308Geobacter lovleyi SZ, complete genomeglycosyl transferase family 22e-1583.6
NC_014652:1091610:1096400109640010982921893Caldicellulosiruptor hydrothermalis 108 chromosome, completeglycosyl transferase family 22e-1583.2
NC_010520:2937981:2939709293970929416281920Clostridium botulinum A3 str. Loch Maree, complete genomeglycosyl transferase, group 2 family protein3e-1583.2
NC_017068:2569609:2589112258911225902391128Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative glycosyl transferase family 2 protein8e-1581.6
NC_016935:7872425:7912976791297679140191044Paenibacillus mucilaginosus 3016 chromosome, complete genomehypothetical protein1e-1480.9
NC_012563:3090954:3094463309446330963881926Clostridium botulinum A2 str. Kyoto, complete genomeglycosyl transferase, group 2 family2e-1480.5
NC_009698:2727203:2730712273071227326131902Clostridium botulinum A str. Hall chromosome, complete genomeglycosyl transferase family protein2e-1480.5
NC_009697:2790277:2793786279378627956871902Clostridium botulinum A str. ATCC 19397 chromosome, completeglycosyl transferase family protein2e-1480.5
NC_009495:2876865:2880374288037428822751902Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeglycosyltransferase2e-1480.5
NC_015757:2343193:2349504234950423507961293Sulfobacillus acidophilus TPY chromosome, complete genomeglycosyl transferase family 23e-1479.7
NC_016884:3219030:3225407322540732266331227Sulfobacillus acidophilus DSM 10332 chromosome, complete genomefamily 2 glycosyl transferase3e-1479.7
NC_012912:2901021:2908248290824829093001053Dickeya zeae Ech1591, complete genomeglycosyl transferase family 24e-1479.3
NC_012658:2930244:2931972293197229338731902Clostridium botulinum Ba4 str. 657 chromosome, complete genomegroup 2 family glycosyl transferase protein6e-1479
NC_010516:2900057:2900057290005729021622106Clostridium botulinum B1 str. Okra, complete genomeglycosyltransferase1e-1377.8
NC_021175:751616:7671537671537683011149Streptococcus oligofermentans AS 1.3089, complete genomeglycosyl transferase family protein2e-1376.6
NC_015563:606783:6135316135316145921062Delftia sp. Cs1-4 chromosome, complete genomefamily 2 glycosyl transferase3e-1376.3
NC_013740:571879:578318578318579067750Acidaminococcus fermentans DSM 20731, complete genomeglycosyl transferase family 21e-1171.2
NC_009486:155651:1635201635201661022583Thermotoga petrophila RKU-1 chromosome, complete genomeglycosyl transferase family protein1e-1068.2
NC_015873:1901939:191660119166011917356756Megasphaera elsdenii DSM 20460, complete genomebeta-19e-1168.2
NC_000853:771746:7821497821497847312583Thermotoga maritima MSB8, complete genomehypothetical protein9e-1168.2
NC_014378:261064:2659612659612682642304Acetohalobium arabaticum DSM 5501 chromosome, complete genomeglycosyl transferase family 21e-1067.8
NC_012108:2065355:206535520653552066158804Desulfobacterium autotrophicum HRM2, complete genomeKdtX3e-1066.6
NC_015633:413587:412805412805413590786Vibrio anguillarum 775 chromosome chromosome I, complete sequencealpha-L-glycero-D-manno-heptose beta-1,4-glucosyltransferase6e-1065.5
NC_015388:1861710:186605818660581866945888Desulfobacca acetoxidans DSM 11109 chromosome, complete genomeglycosyl transferase family 21e-0964.3
NC_013421:4790696:480567748056774806453777Pectobacterium wasabiae WPP163, complete genomeglycosyl transferase family 21e-0964.3
NC_002939:2454686:246959724695972470379783Geobacter sulfurreducens PCA, complete genomeglycosyl transferase, group 2 family protein2e-0963.5
NC_019978:2396000:240374724037472404496750Halobacteroides halobius DSM 5150, complete genomeglycosyl transferase6e-0962
NC_013131:9903320:9903800990380099050141215Catenulispora acidiphila DSM 44928, complete genomeglycosyl transferase family 21e-0861.2
NC_016513:1720006:172933917293391729884546Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeglycosyll transferase, family 22e-0860.5
NC_007517:2632233:265136926513692652118750Geobacter metallireducens GS-15, complete genomeprobable beta-1,4-glucosyltransferase2e-0860.5
NC_008148:583030:591962591962592810849Rubrobacter xylanophilus DSM 9941, complete genomeglycosyl transferase, family 22e-0860.5
NC_002678:426000:4305304305304333252796Mesorhizobium loti MAFF303099, complete genomehypothetical protein2e-0860.1
NC_015185:1414453:143175514317551432516762Desulfurobacterium thermolithotrophum DSM 11699 chromosome,glycosyl transferase family 25e-0858.9
NC_015567:69190:7885978859798691011Serratia sp. AS9 chromosome, complete genomefamily 2 glycosyl transferase7e-0858.5
NC_015566:69190:7885978859798691011Serratia sp. AS12 chromosome, complete genomefamily 2 glycosyl transferase7e-0858.5
NC_008786:2809985:280998528099852810797813Verminephrobacter eiseniae EF01-2, complete genomeglycosyl transferase, family 22e-0757.4
NC_008740:876115:894126894126894875750Marinobacter aquaeolei VT8, complete genomeglycosyl transferase, family 25e-0755.8
NC_010084:1054000:106271710627171063508792Burkholderia multivorans ATCC 17616 chromosome 1, completeglycosyl transferase family protein6e-0755.5
NC_017280:1075435:107922710792271079934708Campylobacter jejuni subsp. jejuni M1 chromosome, complete genomePutative two domain glycosyltransferase9e-0755.1
NC_007643:1781723:1784681178468117857601080Rhodospirillum rubrum ATCC 11170, complete genomeGlycosyl transferase, family 29e-0755.1
NC_015216:1278706:130389213038921304740849Methanobacterium sp. AL-21 chromosome, complete genomefamily 2 glycosyl transferase1e-0654.7
NC_018876:516220:525783525783526697915Methanolobus psychrophilus R15 chromosome, complete genomeglycosyl transferase family 21e-0654.7
NC_013421:3279499:329146332914633292434972Pectobacterium wasabiae WPP163, complete genomeglycosyl transferase family 21e-0654.3
NC_004547:164000:173307173307174074768Erwinia carotovora subsp. atroseptica SCRI1043, complete genomelipopolysaccharide core biosynthesis glycosyl transferase2e-0653.9
NC_009615:3904962:391121339112133912007795Parabacteroides distasonis ATCC 8503 chromosome, complete genomeglycosyl transferase family protein2e-0653.9
NC_007645:1033834:105215710521571052921765Hahella chejuensis KCTC 2396, complete genomeGlycosyltransferase involved in cell wall biogenesis4e-0652.8
NC_014166:2217790:224403122440312244744714Arcobacter nitrofigilis DSM 7299 chromosome, complete genomefamily 2 glycosyl transferase4e-0652.8
NC_006142:262825:267959267959268837879Rickettsia typhi str. Wilmington, complete genomeglucosyltransferase4e-0652.8
NC_017066:262839:267973267973268851879Rickettsia typhi str. TH1527 chromosome, complete genomeglucosyltransferase4e-0652.8
NC_016646:275818:282393282393283181789Pseudovibrio sp. FO-BEG1 plasmid unnamed, complete sequenceBeta 1,4 glucosyltransferase6e-0652
NC_014934:3218423:323424032342403235013774Cellulophaga algicola DSM 14237 chromosome, complete genomeglycosyl transferase family 28e-0651.6