Pre_GI: BLASTP Hits

Some Help

Query: NC_012658:3387774:3402918 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 3402918, End: 3403796, Length: 879

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:3185359:319747031974703198348879Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein1e-122439
NC_009697:3291500:330036333003633301241879Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein1e-122439
NC_009495:3309550:332437433243743325252879Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein1e-122439
NC_010516:3368951:338515233851523386030879Clostridium botulinum B1 str. Okra, complete genomehypothetical protein9e-122436
NC_012563:3556763:356650835665083567380873Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein2e-116418
NC_010674:2417199:242160824216082422381774Clostridium botulinum B str. Eklund 17B, complete genomehypothetical protein6e-36151