Pre_GI: BLASTP Hits

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Query: NC_012658:3126108:3142503 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 3142503, End: 3143831, Length: 1329

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_018691:3437821:3437821343782134392181398Alcanivorax dieselolei B5 chromosome, complete genomeCytosine deaminase-related metal-dependent hydrolase2e-1790.5
NC_009922:411434:4259964259964273301335Alkaliphilus oremlandii OhILAs, complete genomeamidohydrolase1e-37158
NC_007760:645016:6618616618616632581398Anaeromyxobacter dehalogenans 2CP-C, complete genomeformiminoglutamate deiminase1e-1274.7
NC_008712:215499:2323542323542338261473Arthrobacter aurescens TC1 plasmid TC1, complete sequencehydroxyatrazine hydrolase6e-1582.4
NC_006270:2172693:2190058219005821914071350Bacillus licheniformis ATCC 14580, complete genomehypothetical protein3e-1376.6
NC_006322:2173500:2190903219090321922521350Bacillus licheniformis ATCC 14580, complete genomehypothetical protein3e-1376.6
NC_012225:47800:7289572895742261332Brachyspira hyodysenteriae WA1, complete genomechlorohydrolase/aminohydrolase6e-137487
NC_017243:2190000:2218864221886422201951332Brachyspira intermedia PWS/A chromosome, complete genomechlorohydrolase/aminohydrolase1e-137490
NC_014150:2994000:3009675300967530110061332Brachyspira murdochii DSM 12563 chromosome, complete genomeselenium metabolism protein SsnA1e-134479
NC_014330:768232:8043968043968057271332Brachyspira pilosicoli 95/1000 chromosome, complete genomeamidohydrolase family protein SsnA1e-136486
NC_019908:2401577:2415375241537524167061332Brachyspira pilosicoli P43/6/78 chromosome, complete genomechlorohydrolase/aminohydrolase1e-136486
NC_018604:2253539:2267186226718622685171332Brachyspira pilosicoli WesB complete genomeamidohydrolase family protein SsnA1e-136486
NC_009075:1638789:1649346164934616507791434Burkholderia pseudomallei 668 chromosome II, complete sequenceamidohydrolase family protein1e-31137
NC_006351:2759708:2763357276335727647901434Burkholderia pseudomallei K96243 chromosome 2, complete sequencechrolohydrolase7e-32138
NC_016012:236012:2472942472942484511158Candidatus Arthromitus sp. SFB-rat-Yit, complete genomeputative amidohydrolase4e-0653.1
NC_003030:303812:3215643215643228501287Clostridium acetobutylicum ATCC 824, complete genomeCytosine/guanine deaminase related protein6e-0962.4
NC_015687:303810:3215613215613228471287Clostridium acetobutylicum DSM 1731 chromosome, complete genomecytosine/guanine deaminase-like protein6e-0962.4
NC_009697:2984173:3000769300076930020971329Clostridium botulinum A str. ATCC 19397 chromosome, completechlorohydrolase/aminohydrolase0852
NC_009495:3051223:3067819306781930691471329Clostridium botulinum A str. ATCC 3502 chromosome, complete genomechlorohydrolase/aminohydrolase0852
NC_009698:2921097:2937693293769329390211329Clostridium botulinum A str. Hall chromosome, complete genomechlorohydrolase/aminohydrolase0852
NC_012563:3288124:3304801330480133061291329Clostridium botulinum A2 str. Kyoto, complete genomeamidohydrolase family protein0846
NC_010520:3120500:3138168313816831394961329Clostridium botulinum A3 str. Loch Maree, complete genomeamidohydrolase family protein0864
NC_010674:615963:6276806276806290411362Clostridium botulinum B str. Eklund 17B, complete genomehydroxydechloroatrazine ethylaminohydrolase9e-30131
NC_010674:615963:6255716255716269021332Clostridium botulinum B str. Eklund 17B, complete genomeproteoglycan8e-145513
NC_015425:2024154:2047594204759420487511158Clostridium botulinum BKT015925 chromosome, complete genomeamidohydrolase family protein2e-0963.9
NC_010723:575254:5896775896775910081332Clostridium botulinum E3 str. Alaska E43, complete genomeproteoglycan2e-147522
NC_010723:575254:5914445914445928051362Clostridium botulinum E3 str. Alaska E43, complete genomehydroxydechloroatrazine ethylaminohydrolase2e-29130
NC_017179:3540739:3552204355220435535321329Clostridium difficile BI1, complete genomeputative chlorohydrolase/aminohydrolase2e-149529
NC_013315:2232339:2237486223748622387991314Clostridium difficile CD196 chromosome, complete genomeamidohydrolase1e-43177
NC_013315:3532721:3544186354418635455141329Clostridium difficile CD196 chromosome, complete genomechlorohydrolase/aminohydrolase2e-149529
NC_013315:2232339:2242432224243222438561425Clostridium difficile CD196 chromosome, complete genomeamidohydrolase6e-42172
NC_013316:2309694:2322986232298623244101425Clostridium difficile R20291, complete genomeputative amidohydrolase6e-42172
NC_013316:2309694:2318040231804023193531314Clostridium difficile R20291, complete genomeputative amidohydrolase1e-43177
NC_014328:2872721:2893648289364828949521305Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative amidohydrolase5e-35149
NC_014328:2643588:2645078264507826463611284Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeguanine deaminase2e-1273.9
NC_008593:1797000:1820856182085618220131158Clostridium novyi NT, complete genomeAmidohydrolase family protein1e-0654.7
NC_021182:434351:4448354448354461721338Clostridium pasteurianum BC1, complete genomeputative selenium metabolism protein SsnA3e-117422
NC_015859:3346473:3356901335690133584331533Corynebacterium variabile DSM 44702 chromosome, complete genomeputative amidohydrolase5e-24112
NC_011527:1443076:1441635144163514430891455Coxiella burnetii CbuG_Q212, complete genomechlorohydrolase/deaminase family protein7e-35148
NC_011528:1282691:1281250128125012827041455Coxiella burnetii CbuK_Q154, complete genomechlorohydrolase/deaminase family protein7e-35148
NC_009727:1542000:1542598154259815439531356Coxiella burnetii Dugway 7E9-12, complete genomeamidohydrolase family protein8e-35148
NC_015388:719669:7369847369847383211338Desulfobacca acetoxidans DSM 11109 chromosome, complete genome5-methylthioadenosine/S- adenosylhomocysteinedeaminase1e-33144
NC_018515:1354511:1369392136939213707231332Desulfosporosinus meridiei DSM 13257 chromosome, complete genomecytosine deaminase1e-23111
NC_016584:4860360:4883128488312848844321305Desulfosporosinus orientis DSM 765 chromosome, complete genomecytosine deaminase1e-50201
NC_016584:1436710:1436710143671014380411332Desulfosporosinus orientis DSM 765 chromosome, complete genomecytosine deaminase2e-22107
NC_011297:767333:7889637889637902431281Dictyoglomus thermophilum H-6-12, complete genomeamidohydrolase family1e-48194
NC_011297:787932:7889637889637902431281Dictyoglomus thermophilum H-6-12, complete genomeamidohydrolase family1e-48194
NC_014306:3006028:3035670303567030370971428Erwinia billingiae Eb661, complete genomeAmidohydrolase 12e-1273.9
NC_014666:7222000:7226601722660172280371437Frankia sp. EuI1c chromosome, complete genomeamidohydrolase5e-1995.9
NC_020210:2133996:2179010217901021804371428Geobacillus sp. GHH01, complete genomehydroxydechloroatrazine ethylaminohydrolase8e-26118
NC_002939:1866651:1872319187231918735811263Geobacter sulfurreducens PCA, complete genomechlorohydrolase, Atz/Trz family2e-1170.5
NC_016027:2387832:2392715239271523940791365Gluconacetobacter xylinus NBRC 3288, complete genomehydroxydechloroatrazine ethylaminohydrolase2e-23110
NC_016906:839406:8380818380818394091329Gordonia polyisoprenivorans VH2 chromosome, complete genomeputative amidohydrolase1e-21104
NC_014654:2311818:2317473231747323188491377Halanaerobium sp. 'sapolanicus' chromosome, complete genomeS-adenosylhomocysteine deaminase1e-23110
NC_014654:2311818:2316109231610923174401332Halanaerobium sp. 'sapolanicus' chromosome, complete genomeselenium metabolism protein SsnA6e-112404
NC_006395:217139:2407492407492420831335Haloarcula marismortui ATCC 43049 plasmid pNG700, completeN-ethylammeline chlorohydrolase4e-34146
NC_019978:1022209:1037097103709710384281332Halobacteroides halobius DSM 5150, complete genomeputative selenium metabolism protein SsnA2e-108392
NC_019978:1022209:1035696103569610370541359Halobacteroides halobius DSM 5150, complete genomecytosine deaminase-like metal-dependent hydrolase4e-27122
NC_013967:2760473:2760473276047327617861314Haloferax volcanii DS2 chromosome, complete genomecytosine deaminase4e-30132
NC_015658:1:7707770790291323Halopiger xanaduensis SH-6 plasmid pHALXA01, complete sequenceS-adenosylhomocysteine deaminase2e-35150
NC_012029:45462:6423164231655651335Halorubrum lacusprofundi ATCC 49239 chromosome 1, complete genomeamidohydrolase3e-35149
NC_013744:159861:1751081751081764361329Haloterrigena turkmenica DSM 5511 plasmid pHTUR01, completeamidohydrolase4e-33142
NC_014632:113420:1321301321301334581329Ilyobacter polytropus DSM 2926 chromosome, complete genomeselenium metabolism protein SsnA8e-154543
NC_016612:5231065:5264156526415652655531398Klebsiella oxytoca KCTC 1686 chromosome, complete genomeamidohydrolase family protein4e-0756.2
NC_009654:4624459:4633743463374346351011359Marinomonas sp. MWYL1, complete genomeamidohydrolase2e-1997.4
NC_000909:1517461:1517461151746115187231263Methanocaldococcus jannaschii DSM 2661, complete genomeN-ethylammeline chlorohydrolase (trzA)1e-47191
NC_013665:2132000:2132670213267021338421173Methanocella paludicola SANAE, complete genomeamidohydrolase family protein3e-1790.1
NC_007955:1254051:1273264127326412745681305Methanococcoides burtonii DSM 6242, complete genomeamidohydrolase1e-50200
NC_009635:1067334:1081542108154210827201179Methanococcus aeolicus Nankai-3 chromosome, complete genomechlorohydrolase2e-0757.8
NC_009051:1074993:1076713107671310780201308Methanoculleus marisnigri JR1, complete genomeamidohydrolase2e-35150
NC_014253:729996:7492297492297505211293Methanohalobium evestigatum Z-7303 chromosome, complete genomeamidohydrolase1e-54214
NC_018876:996855:1006097100609710073951299Methanolobus psychrophilus R15 chromosome, complete genomeN-ethylammeline chlorohydrolase7e-47188
NC_019977:1897556:1907287190728719085881302Methanomethylovorans hollandica DSM 15978, complete genomecytosine deaminase-like metal-dependent hydrolase2e-51203
NC_015676:546895:5468955468955482051311Methanosalsum zhilinae DSM 4017 chromosome, complete genomeamidohydrolase3e-48192
NC_003901:2685716:2717501271750127188741374Methanosarcina mazei Go1, complete genomeN-ethylammeline chlorohydrolase7e-57221
NC_007681:218921:2462962462962475731278Methanosphaera stadtmanae DSM 3091, complete genomepredicted metal-dependent hydrolase1e-39164
NC_014658:417537:4402914402914414481158Methanothermus fervidus DSM 2088 chromosome, complete genomes-adenosylhomocysteine deaminase4e-1066.6
NC_014315:2327083:2329675232967523310031329Nitrosococcus watsoni C-113 chromosome, complete genomeamidohydrolase9e-31135
NC_015731:2811579:2811579281157928129101332Nitrosomonas sp. Is79A3 chromosome, complete genome5-methylthioadenosine/S-adenosylhomocysteine deaminase4e-29129
NC_014210:2638773:2658379265837926597401362Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,amidohydrolase3e-1893.6
NC_015580:1328361:1338694133869413401661473Novosphingobium sp. PP1Y, complete genomecytosine deaminase and related metal-dependent hydrolases1e-1068.2
NC_013406:1217385:1274597127459712759611365Paenibacillus sp. Y412MC10 chromosome, complete genomeguanine deaminase4e-1273.2
NC_008609:3732192:3763808376380837650941287Pelobacter propionicus DSM 2379, complete genomeamidohydrolase8e-1892
NC_010003:795355:8110198110198123471329Petrotoga mobilis SJ95, complete genomeamidohydrolase4e-32139
NC_004129:4993974:5019392501939250207231332Pseudomonas fluorescens Pf-5, complete genomeN-ethylammeline chlorohydrolase1e-27124
NC_010501:3448389:3475578347557834769631386Pseudomonas putida W619, complete genomeamidohydrolase1e-33144
NC_015474:72103:8973989739910071269Pyrococcus sp. NA2 chromosome, complete genomeN-ethylammeline chlorohydrolase3e-43176
NC_008148:3024867:3044409304440930459081500Rubrobacter xylanophilus DSM 9941, complete genomeamidohydrolase2e-0964.3
NC_016633:14000:1419814198155981401Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomecytosine deaminase5e-21102
NC_014364:3001597:3029161302916130305311371Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeamidohydrolase4e-27122
NC_014364:394899:4563214563214576761356Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeamidohydrolase2e-38160
NC_014364:2863686:2863686286368628650921407Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeamidohydrolase7e-39162
NC_015152:2622000:2633671263367126350021332Spirochaeta sp. Buddy chromosome, complete genomeS-adenosylhomocysteine deaminase3e-24113
NC_014623:7133149:7146017714601771473511335Stigmatella aurantiaca DW4/3-1 chromosome, complete genome5-methylthioadenosine/s-adenosylhomocysteine deaminase7e-45181
NC_012589:1434707:1456589145658914578241236Sulfolobus islandicus L.S.2.15, complete genomeamidohydrolase6e-22105
NC_012622:1333000:1345962134596213471971236Sulfolobus islandicus Y.G.57.14 chromosome, complete genomeamidohydrolase6e-22105
NC_015958:1516944:1531836153183615331341299Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genome5-methylthioadenosine/S-adenosylhomocysteine deaminase2e-53210
NC_015865:3657:90349034102901257Thermococcus sp. 4557 chromosome, complete genomemetal-dependent amidohydrolase3e-31136
NC_015681:1201926:1204632120463212059421311Thermodesulfatator indicus DSM 15286 chromosome, complete genomeamidohydrolase3e-32140
NC_015499:309394:3175213175213188011281Thermodesulfobium narugense DSM 14796 chromosome, complete genome5-methylthioadenosine/S- adenosylhomocysteinedeaminase1e-26121
NC_014377:1897857:1917522191752219186791158Thermosediminibacter oceani DSM 16646 chromosome, complete genomeamidohydrolase9e-0652
NC_011653:331986:3521323521323534151284Thermosipho africanus TCF52B, complete genomeprotein SsnA2e-64246
NC_007404:974461:1007134100713410084591326Thiobacillus denitrificans ATCC 25259, complete genomeN-ethylammeline chlorohydrolase1e-28128
NC_015151:1403500:1419154141915414204911338Vulcanisaeta moutnovskia 768-28 chromosome, complete genomeamidohydrolase1e-21104