Pre_GI: BLASTP Hits

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Query: NC_012658:2930244:2936480 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 2936480, End: 2938915, Length: 2436

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:2727203:2735222273522227376572436Clostridium botulinum A str. Hall chromosome, complete genomeflagellar hook-associated protein 201460
NC_009697:2790277:2798296279829628007312436Clostridium botulinum A str. ATCC 19397 chromosome, completeflagellar hook-associated protein 201460
NC_009495:2876865:2884884288488428873192436Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeflagellar hook-associated protein 201460
NC_012563:3090954:3098973309897331014082436Clostridium botulinum A2 str. Kyoto, complete genomeFlagellar hook-associated protein 201460
NC_010520:2937981:2944323294432329467582436Clostridium botulinum A3 str. Loch Maree, complete genomeFlagellar hook-associated protein 201429
NC_009699:2901497:2908502290850229109402439Clostridium botulinum F str. Langeland chromosome, complete genomeflagellar hook-associated protein 201414
NC_017297:2905138:2908640290864029110782439Clostridium botulinum F str. 230613 chromosome, complete genomeFlagellar hook-associated protein 201414
NC_010516:2900057:2903973290397329064352463Clostridium botulinum B1 str. Okra, complete genomeflagellar hook-associated protein01124
NC_015913:624859:6321566321566345552400Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomeflagellar hook-associated protein3e-106386
NC_016012:561687:5717695717695741622394Candidatus Arthromitus sp. SFB-rat-Yit, complete genomeflagellar hook-associated protein2e-105384
NC_020134:2772500:2772942277294227749091968Clostridium stercorarium subsp. stercorarium DSM 8532, completeflagellar hook-associated protein 28e-64245
NC_016584:4363382:4375937437593743778321896Desulfosporosinus orientis DSM 765 chromosome, complete genomeflagellar capping protein4e-48193
NC_021182:2921000:2928875292887529308361962Clostridium pasteurianum BC1, complete genomeflagellar capping protein6e-48192
NC_004557:1826977:1830649183064918323191671Clostridium tetani E88, complete genomeflagellar cap protein fliD4e-47190
NC_015172:1075592:1086694108669410885951902Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeflagellar hook-associated 2 domain-containing protein1e-42175
NC_015425:1207314:1219749121974912207741026Clostridium botulinum BKT015925 chromosome, complete genomeflagellar cap protein fliD4e-42174
NC_014614:2434017:2456460245646024580671608Clostridium sticklandii, complete genomeflagellar hook-associated capping protein 2 (HAP2)1e-39165
NC_014377:1546124:1558623155862315605421920Thermosediminibacter oceani DSM 16646 chromosome, complete genomeflagellar hook-associated 2 domain protein2e-35151
NC_015519:924000:9282699282699301281860Tepidanaerobacter sp. Re1 chromosome, complete genomeflagellar hook-associated 2 domain-containing protein9e-35149
NC_009922:2672396:2695052269505226970401989Alkaliphilus oremlandii OhILAs, complete genomeflagellar hook-associated 2 domain protein2e-34148
NC_015660:391627:4112594112594128301572Geobacillus thermoglucosidasius C56-YS93 chromosome, completeflagellar hook-associated 2 domain-containing protein4e-34147
NC_014650:376070:3998783998784014491572Geobacillus sp. Y4.1MC1 chromosome, complete genomeflagellar hook-associated 2 domain-containing protein4e-34147
NC_010337:748467:7667547667547683341581Heliobacterium modesticaldum Ice1, complete genomeflagellar hook-associated protein 26e-34146
NC_017295:2286911:2297673229767322995891917Clostridium acetobutylicum EA 2018 chromosome, complete genomeFlagellar hook-associated protein FliD1e-33145
NC_015565:1920329:1925979192597919277091731Desulfotomaculum carboxydivorans CO-1-SRB chromosome, completeflagellar hook-associated 2 domain-containing protein1e-33145
NC_006510:3133965:3135321313532131368231503Geobacillus kaustophilus HTA426, complete genomeflagellar hook-associated protein1e-32142
NC_018664:239000:2612382612382630701833Clostridium acidurici 9a chromosome, complete genomeflagellar hook-associated protein 21e-32142
NC_020210:3169258:3169840316984031713451506Geobacillus sp. GHH01, complete genomeflagellar hook-associated protein II9e-33142
NC_013411:3251500:3251509325150932530111503Geobacillus sp. Y412MC61, complete genomeflagellar hook-associated 2 domain protein4e-31137
NC_010424:1857062:1874966187496618767861821Candidatus Desulforudis audaxviator MP104C, complete genomeflagellar hook-associated 2 domain protein2e-29131
NC_012914:6583000:6590018659001865917961779Paenibacillus sp. JDR-2, complete genomeflagellar hook-associated 2 domain protein3e-29131
NC_019896:577594:5905905905905920861497Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completeFlagellar protein Cap6e-29130
NC_019897:128610:1802221802221817601539Thermobacillus composti KWC4 chromosome, complete genomeflagellar capping protein6e-29130
NC_017195:3426000:3431830343183034333261497Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completeflagellar hook-associated protein 26e-29130
NC_009454:2201987:2202923220292322044791557Pelotomaculum thermopropionicum SI, complete genomeflagellar capping protein1e-28128
NC_013791:1082951:1092897109289710947351839Bacillus pseudofirmus OF4 chromosome, complete genomeflagellar hook-associated protein FliD1e-28128
NC_010674:828191:8313318313318334182088Clostridium botulinum B str. Eklund 17B, complete genomeflagellar cap protein FliD2e-28128
NC_014328:1046958:1066406106640610687632358Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeflagellar hook-associated protein6e-28126
NC_010723:801215:8085098085098105962088Clostridium botulinum E3 str. Alaska E43, complete genomeflagellar cap protein FliD5e-27123
NC_004193:2553630:2559639255963925611201482Oceanobacillus iheyensis HTE831, complete genomeflagellar hook-associated protein 22e-26121
NC_011830:4399642:4409276440927644108081533Desulfitobacterium hafniense DCB-2, complete genomeflagellar hook-associated 2 domain protein2e-26121
NC_009253:2615777:2635175263517526370131839Desulfotomaculum reducens MI-1 chromosome, complete genomeflagellar hook-associated 2 domain-containing protein1e-24115
NC_012491:5628000:5634609563460956361201512Brevibacillus brevis NBRC 100599, complete genomeflagellar hook-associated protein 21e-20102
NC_016641:945284:9490099490099504811473Paenibacillus terrae HPL-003 chromosome, complete genomeflagellar capping protein3e-1997.8
NC_020291:4944835:4985389498538949869301542Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeflagellar hook-associated protein 25e-1997.1
NC_013406:6568273:658218365821836583118936Paenibacillus sp. Y412MC10 chromosome, complete genomeflagellar hook-associated 2 domain-containing protein5e-1893.6
NC_009617:4946000:4947583494758349491601578Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeflagellar hook-associated 2 domain-containing protein2e-1689
NC_012778:263241:2632412632412653552115Eubacterium eligens ATCC 27750, complete genomeflagellar hook-associated protein 22e-1584.7
NC_012781:3087467:3092978309297830956712694Eubacterium rectale ATCC 33656, complete genomeflagellar capping protein9e-1479.7
NC_015589:1240197:1259615125961512621192505Desulfotomaculum ruminis DSM 2154 chromosome, complete genomeflagellar hook-associated 2 domain-containing protein1e-1172.4
NC_014387:605711:6217866217866233301545Butyrivibrio proteoclasticus B316 chromosome 1, complete genomeflagellar hook-associated protein FliD12e-0862