Pre_GI: BLASTP Hits

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Query: NC_012658:2584355:2616075 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 2616075, End: 2617124, Length: 1050

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012563:2721658:2732455273245527335041050Clostridium botulinum A2 str. Kyoto, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase5e-177620
NC_014328:1405484:1408910140891014099591050Clostridium ljungdahlii ATCC 49587 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase9e-135479
NC_020291:1464500:1466848146684814678971050Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG5e-127454
NC_016627:2799453:2822345282234528234091065Clostridium clariflavum DSM 19732 chromosome, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase2e-126452
NC_011898:513835:5151325151325161931062Clostridium cellulolyticum H10, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase7e-120430
NC_019970:1343670:1360613136061313616771065Thermoanaerobacterium thermosaccharolyticum M0795, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase2e-117422
NC_011979:2641500:2641583264158326426351053Geobacter sp. FRC-32, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase1e-115416
NC_014973:3290545:3314736331473633157971062Geobacter sp. M18 chromosome, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase1e-113409
NC_014152:1430156:1429092142909214301591068Thermincola sp. JR, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase4e-113408
NC_016629:3254000:3266400326640032674941095Desulfovibrio africanus str. Walvis Bay chromosome, complete4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase3e-110398
NC_011830:3904034:3932245393224539333391095Desulfitobacterium hafniense DCB-2, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase1e-107390
NC_013939:1812259:1817530181753018185821053Deferribacter desulfuricans SSM1, complete genome4-hydroy-3-methylbut-2-en-1-yl diphosphate synthase2e-107389
NC_007907:2879568:2903451290345129045451095Desulfitobacterium hafniense Y51, complete genomehypothetical protein3e-107388
NC_014387:1175927:1176990117699011780541065Butyrivibrio proteoclasticus B316 chromosome 1, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase IspG3e-106385
NC_012778:841934:8658488658488669031056Eubacterium eligens ATCC 27750, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase8e-104377
NC_017294:758992:7712407712407722471008Candidatus Arthromitus sp. SFB-mouse-Yit, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase8e-103373
NC_017303:1420758:1422755142275514239301176Corynebacterium pseudotuberculosis I19 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase2e-101369
NC_017031:1420738:1422735142273514239101176Corynebacterium pseudotuberculosis P54B96 chromosome, complete4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase2e-101369
NC_016781:1408235:1422870142287014240451176Corynebacterium pseudotuberculosis 3/99-5 chromosome, complete4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase2e-101369
NC_014329:1407880:1422932142293214241071176Corynebacterium pseudotuberculosis FRC41 chromosome, complete4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase2e-101369
NC_004344:622318:6417796417796428791101Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis,hypothetical protein2e-99362
NC_011601:2854178:2876115287611528772331119Escherichia coli O127:H6 str. E2348/69 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase2e-97355
NC_018643:1037456:1056095105609510571951101Alpha proteobacterium HIMB5 chromosome, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase5e-96351
NC_016893:181951:1889621889621900441083Wigglesworthia glossinidia endosymbiont of Glossina morsitans1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase9e-96350
NC_015380:99919:1151291151291162321104Candidatus Pelagibacter sp. IMCC9063 chromosome, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase2e-95349
NC_010159:409500:4335964335964347231128Yersinia pestis Angola, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase3e-94345
NC_010634:3269010:3273970327397032750971128Yersinia pseudotuberculosis PB1/+, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase3e-94345
NC_017168:2560000:2560071256007125611981128Yersinia pestis A1122 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase3e-94345
NC_014935:1999653:2001239200123920023061068Nitratifractor saLSUginis DSM 16511 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-93343
NC_016632:1278500:1294720129472012958351116Serratia symbiotica str. 'Cinara cedri' chromosome, complete1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase2e-93342
NC_009850:661802:6641326641326651931062Arcobacter butzleri RM4018, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase2e-91336
NC_007205:499808:5062125062125073121101Candidatus Pelagibacter ubique HTCC1062, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase3e-91335
NC_020133:2144752:2168373216837321695361164Mycobacterium liflandii 128FXT, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, IspG7e-91334
NC_013947:5431741:5436180543618054373491170Stackebrandtia nassauensis DSM 44728 chromosome, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase7e-91334
NC_010612:2215724:2237857223785722390201164Mycobacterium marinum M, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, IspG1e-90333
NC_009718:1024000:1041035104103510421231089Fervidobacterium nodosum Rt17-B1, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase3e-90332
NC_019673:6778401:6800071680007168011591089Saccharothrix espanaensis DSM 44229 complete genome(E)-4-hydroxy-3-methylbut-2-enyl- diphosphatesynthase4e-90331
NC_013947:2113941:2113941211394121150891149Stackebrandtia nassauensis DSM 44728 chromosome, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase3e-89328
NC_013131:7401253:7401253740125374023681116Catenulispora acidiphila DSM 44928, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase3e-89328
NC_014109:326500:3285103285103296551146Candidatus Riesia pediculicola USDA chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase7e-89327
NC_017095:1333810:1342284134228413433841101Fervidobacterium pennivorans DSM 9078 chromosome, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase6e-86317
NC_017096:779550:7949047949047959471044Caldisericum exile AZM16c01, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-84313
NC_007493:1672163:1672163167216316732961134Rhodobacter sphaeroides 2.4.1 chromosome 1, complete sequence4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase3e-84311
NC_010003:2134878:2151942215194221529911050Petrotoga mobilis SJ95, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase2e-77289
NC_014909:589677:6064026064026074901089Candidatus Blochmannia vafer str. BVAF chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase8e-75280
NC_005071:835005:8517748517748529941221Prochlorococcus marinus str. MIT 9313, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase6e-65248
NC_007513:1126914:1145797114579711470021206Synechococcus sp. CC9902, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase2e-64246
NC_005070:1144777:1164997116499711661931197Synechococcus sp. WH 8102, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-60233
NC_019902:2943719:2960955296095529621961242Thioalkalivibrio nitratireducens DSM 14787, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase8e-53207
NC_010161:2381195:2386672238667223879131242Bartonella tribocorum CIP 105476, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase3e-52205
NC_011901:1398376:1426647142664714278761230Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, complete4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase5e-52205
NC_014932:1387818:1395984139598413972221239Bartonella clarridgeiae 73, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase7e-52204
NC_012846:2154000:2157272215727221585131242Bartonella grahamii as4aup, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-51204
NC_007086:2887875:2967977296797729692421266Xanthomonas campestris pv. campestris str. 8004, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase3e-49196
NC_015277:2702056:2702056270205627040682013Sphingobacterium sp. 21 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase5e-49195
NC_015222:1127675:1137812113781211390501239Nitrosomonas sp. AL212 chromosome, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase7e-49194
NC_008781:1973826:1995694199569419969681275Polaromonas naphthalenivorans CJ2, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase2e-48192
NC_017439:45953:6563065630674381809Chlamydia trachomatis E/150 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-46187
NC_010287:372000:3878153878153896231809Chlamydia trachomatis 434/Bu, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase9e-47187
NC_008783:119758:1334981334981347541257Bartonella bacilliformis KC583, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase7e-47187
NC_017437:49643:6607866078679071830Chlamydia trachomatis A2497 chromosome, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase2e-46186
NC_007429:49647:6619066190679981809Chlamydia trachomatis A/HAR-13, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-46186
NC_012686:49643:6614466144679521809Chlamydia trachomatis B/Jali20/OT chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-46186
NC_012687:49640:6607566075678831809Chlamydia trachomatis B/TZ1A828/OT chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-46186
NC_016798:49643:6607866078678861809Chlamydia trachomatis A2497, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase1e-46186
NC_017429:45965:6553365533673411809Chlamydia trachomatis G/9768 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-46186
NC_017430:49052:6561865618674261809Chlamydia trachomatis G/11222 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-46186
NC_017432:45965:6553365533673411809Chlamydia trachomatis G/9301 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-46186
NC_017440:45965:6553365533673411809Chlamydia trachomatis G/11074 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-46186
NC_008536:1462344:1473671147367114749181248Solibacter usitatus Ellin6076, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase4e-46185
NC_007799:555900:5621455621455633741230Ehrlichia chaffeensis str. Arkansas, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-45183
NC_005295:796437:8094008094008106681269Ehrlichia ruminantium str. Welgevonden, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase3e-45182
NC_006832:776286:7892497892497905171269Ehrlichia ruminantium str. Welgevonden, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase3e-45182
NC_006831:772737:7856977856977869651269Ehrlichia ruminantium str. Gardel, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-44181
NC_006833:1011537:1030146103014610314351290Wolbachia endosymbiont strain TRS of Brugia malayi, complete4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase7e-43174
NC_013009:721823:7282377282377294811245Neorickettsia risticii str. Illinois, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase4e-41168
NC_003228:4895326:4903652490365249055321881Bacteroides fragilis NCTC 9343, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase5e-41168
NC_007798:703922:7103347103347115781245Neorickettsia sennetsu str. Miyayama, complete genome1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase6e-41168
NC_016776:4982094:4990423499042349923031881Bacteroides fragilis 638R, complete genomeputative GcpE terpenoid biosynthesis protein7e-41168
NC_006347:4961865:4970192497019249720721881Bacteroides fragilis YCH46, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase7e-41168
NC_015744:367142:3875243875243892301707Chlamydia trachomatis L2c chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase2e-40166
NC_018681:7624000:763143876314387631827390Nocardia brasiliensis ATCC 700358 chromosome, complete genome4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase1e-1377.8