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Query: NC_012658:2584355:2608772 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 2608772, End: 2609089, Length: 318

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:2367171:239494423949442395261318Clostridium botulinum A str. Hall chromosome, complete genomeribosomal protein L7Ae family protein2e-54210
NC_009697:2394826:242259924225992422916318Clostridium botulinum A str. ATCC 19397 chromosome, completeribosomal protein L7Ae family protein2e-54210
NC_009495:2524000:255057625505762550893318Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeribosomal protein L7Ae family protein2e-54210
NC_012563:2721658:272508727250872725404318Clostridium botulinum A2 str. Kyoto, complete genomerRNA-binding protein2e-54210
NC_010516:2511035:253879925387992539116318Clostridium botulinum B1 str. Okra, complete genomeribosomal protein L7Ae family protein4e-54209
NC_010520:2585014:261332926133292613643315Clostridium botulinum A3 str. Loch Maree, complete genomeribosomal protein L7Ae family protein1e-53207
NC_008262:1835613:185335418533541853656303Clostridium perfringens SM101, complete genomeRibosomal protein L7Ae superfamily1e-1995.1
NC_020291:1464500:147015114701511470465315Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeribosomal protein HS6-type3e-1787.4
NC_014328:1405484:141204714120471412364318Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative ribosomal protein8e-1579
NC_011898:513835:522857522857523195339Clostridium cellulolyticum H10, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd452e-1168.2
NC_019970:1343670:135348313534831353803321Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeribosomal protein HS6-type (S12/L30/L7a)5e-0960.1
NC_016627:2799453:281967328196732820017345Clostridium clariflavum DSM 19732 chromosome, complete genomeribosomal protein HS6-type (S12/L30/L7a)6e-0959.3
NC_010001:3369500:338067233806723381019348Clostridium phytofermentans ISDg, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd452e-0857.8
NC_014387:1175927:118605911860591186385327Butyrivibrio proteoclasticus B316 chromosome 1, complete genomeribosomal protein L7A8e-0855.8
NC_017179:1378875:138829013882901388601312Clostridium difficile BI1, complete genomeribosomal protein3e-0753.9
NC_013315:1370000:137851613785161378827312Clostridium difficile CD196 chromosome, complete genomeribosomal protein3e-0753.9
NC_014103:3985897:399760639976063997905300Bacillus megaterium DSM319 chromosome, complete genome50S ribosomal protein L7AE5e-0753.1
NC_012121:897866:908780908780909085306Staphylococcus carnosus subsp. carnosus TM300, complete genomeputative ribosomal_L7Ae protein family protein5e-0753.1
NC_014376:3214222:322451232245123224910399Clostridium saccharolyticum WM1 chromosome, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd452e-0651.2
NC_020134:1173000:117874311787431179033291Clostridium stercorarium subsp. stercorarium DSM 8532, completeribosomal protein HS6-type2e-0650.8
NC_017353:1699652:170894417089441709261318Staphylococcus lugdunensis N920143, complete genomeputative ribosomal protein4e-0650.1
NC_009674:2551759:256160425616042561915312Bacillus cytotoxicus NVH 391-98 chromosome, complete genomehypothetical protein7e-0649.3
NC_010184:3675424:368562536856253685936312Bacillus weihenstephanensis KBAB4, complete genomeribosomal protein L7Ae/L30e/S12e/Gadd457e-0649.3