Pre_GI: BLASTP Hits

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Query: NC_012658:2584355:2587895 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 2587895, End: 2588761, Length: 867

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010516:2511035:251764525176452518511867Clostridium botulinum B1 str. Okra, complete genomeprenyltransferase, UbiA family1e-153542
NC_010520:2585014:259217725921772593043867Clostridium botulinum A3 str. Loch Maree, complete genomeprenyltransferase, UbiA family3e-153540
NC_009698:2367171:237379123737912374657867Clostridium botulinum A str. Hall chromosome, complete genomephosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase6e-153540
NC_009697:2394826:240144624014462402312867Clostridium botulinum A str. ATCC 19397 chromosome, completephosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase6e-153540
NC_009495:2524000:252942325294232530289867Clostridium botulinum A str. ATCC 3502 chromosome, complete genomephosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase6e-153540
NC_012563:2680246:270393527039352704801867Clostridium botulinum A2 str. Kyoto, complete genomeprenyltransferase, UbiA family8e-153539
NC_009699:2576500:257816025781602579026867Clostridium botulinum F str. Langeland chromosome, complete genomephosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase8e-153539
NC_017297:2575306:257829925782992579165867Clostridium botulinum F str. 230613 chromosome, complete genomeprenyltransferase, UbiA family8e-153539
NC_012914:469117:499746499746500657912Paenibacillus sp. JDR-2, complete genomeUbiA prenyltransferase5e-64244
NC_014253:1197005:122868712286871229586900Methanohalobium evestigatum Z-7303 chromosome, complete genomeprenyltransferase UbiA1e-62239
NC_011725:4870223:487235048723504873237888Bacillus cereus B4264 chromosome, complete genomeUbiA prenyltransferase1e-60233
NC_009523:2769154:276915427691542770137984Roseiflexus sp. RS-1 chromosome, complete genomeUbiA prenyltransferase5e-57221
NC_014960:1735786:178143217814321782310879Anaerolinea thermophila UNI-1, complete genomeputative prenyltransferase9e-54210
NC_014394:3036758:306679630667963067671876Gallionella capsiferriformans ES-2 chromosome, complete genomeUbiA prenyltransferase1e-53209
NC_007484:2222474:223273322327332233605873Nitrosococcus oceani ATCC 19707, complete genomeUbiA prenyltransferase1e-50199
NC_011959:972798:989065989065990006942Thermomicrobium roseum DSM 5159, complete genomeUbiA prenyltransferase:PepSY-associated TM helix7e-50197
NC_015416:1571451:157542515754251576324900Methanosaeta concilii GP-6 chromosome, complete genomeUbiA family prenyltransferase2e-47189
NC_008740:1815743:184599418459941846884891Marinobacter aquaeolei VT8, complete genomeUbiA prenyltransferase6e-46184
NC_009379:304222:324082324082324966885Polynucleobacter sp. QLW-P1DMWA-1, complete genomeUbiA prenyltransferase5e-45181
NC_020134:134875:136449136449137306858Clostridium stercorarium subsp. stercorarium DSM 8532, completeprenyltransferase, UbiA family1e-44180
NC_019757:4878417:489256248925624893548987Cylindrospermum stagnale PCC 7417, complete genome4-hydroxybenzoate polyprenyltransferase-like prenyltransferase4e-44178
NC_018868:3943088:395703439570343957897864Simiduia agarivorans SA1 = DSM 21679 chromosome, complete genomephosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase1e-43176
NC_013440:5543667:556059155605915561481891Haliangium ochraceum DSM 14365, complete genomeUbiA prenyltransferase2e-41169
NC_010814:2074266:208509820850982085952855Geobacter lovleyi SZ, complete genomeUbiA prenyltransferase5e-37154
NC_008609:2254392:227106822710682271925858Pelobacter propionicus DSM 2379, complete genomeUbiA prenyltransferase1e-36153
NC_007517:1561466:157343115734311574291861Geobacter metallireducens GS-15, complete genomehypothetical protein3e-36152
NC_002939:1634843:164731116473111648165855Geobacter sulfurreducens PCA, complete genomehypothetical protein5e-36151
NC_014033:1664500:167985716798571680735879Prevotella ruminicola 23 chromosome, complete genomeprenyltransferase, UbiA family1e-35150
NC_015563:6357653:637122663712266372119894Delftia sp. Cs1-4 chromosome, complete genomeUbiA prenyltransferase1e-35150
NC_002977:2719774:274676127467612747651891Methylococcus capsulatus str. Bath, complete genomehypothetical protein4e-34145
NC_015501:1200411:120211812021181203008891Porphyromonas asaccharolytica DSM 20707 chromosome, completeUbiA prenyltransferase1e-29130
NC_018645:2492779:249277924927792493633855Desulfobacula toluolica Tol2, complete genome4-hydroxybenzoate octaprenyltransferase UbiA5e-29128
NC_015593:2914384:2927765292776529292041440Sphingobium chlorophenolicum L-1 chromosome chromosome 1, completeUbiA prenyltransferase1e-20100
NC_015942:2943127:2950554295055429519841431Acidithiobacillus ferrivorans SS3 chromosome, complete genomeUbiA prenyltransferase7e-2097.8
NC_007298:1824335:1837712183771218392231512Dechloromonas aromatica RCB, complete genomeUbiA prenyltransferase:PepSY-associated TM helix4e-1995.1
NC_017267:3982619:3984611398461139860561446Xanthomonas oryzae pv. oryzicola BLS256 chromosome, completeintegral membrane protein3e-1892.8
NC_015508:251354:2665892665892680581470Agrobacterium sp. H13-3 chromosome linear, complete sequenceubiA prenyltransferase family protein1e-1790.1
NC_015947:568124:5813605813605828231464Burkholderia sp. JV3 chromosome, complete genomeUbiA prenyltransferase3e-1789
NC_009937:4350132:436387443638744364797924Azorhizobium caulinodans ORS 571, complete genomenodulation protein noeC9e-1787.4
NC_008554:156744:167066167066167608543Syntrophobacter fumaroxidans MPOB, complete genomeUbiA prenyltransferase2e-1686.3
NC_015422:704500:7571647571647586121449Alicycliphilus denitrificans K601 chromosome, complete genomeUbiA prenyltransferase1e-1584
NC_011071:572346:5887255887255901431419Stenotrophomonas maltophilia R551-3, complete genomeUbiA prenyltransferase2e-1583.2
NC_011666:2335765:2335765233576523372191455Methylocella silvestris BL2, complete genomeUbiA prenyltransferase4e-1582.4
NC_015376:1431728:1441747144174714432161470Burkholderia gladioli BSR3 chromosome chromosome 2, complete4-hydroxybenzoate octaprenyltransferase2e-1480.1
NC_008554:156744:165054165054165428375Syntrophobacter fumaroxidans MPOB, complete genomeputative transmembrane potein3e-1375.9
NC_014207:1366766:1370099137009913715351437Methylotenera sp. 301 chromosome, complete genomeUbiA prenyltransferase1e-1273.9
NC_008702:369965:3722363722363736841449Azoarcus sp. BH72, complete genome4-hydroxybenzoate octaprenyltransferase6e-1271.6
NC_014221:2943950:2942484294248429439531470Truepera radiovictrix DSM 17093 chromosome, complete genomeUbiA prenyltransferase1e-1067.4
NC_015578:247266:260934260934261893960Treponema primitia ZAS-2 chromosome, complete genomeprenyltransferase, UbiA family3e-1066.2