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Query: NC_012658:2584355:2586237 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 2586237, End: 2586593, Length: 357

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2575306:257664425766442577000357Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein2e-58223
NC_009699:2576500:257650525765052576861357Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein2e-58223
NC_012563:2680246:270228027022802702636357Clostridium botulinum A2 str. Kyoto, complete genomemultidrug resistance protein, SMR family2e-58223
NC_009698:2367171:237213623721362372492357Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein3e-58223
NC_009697:2394826:239979123997912400147357Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein3e-58223
NC_009495:2524000:252776825277682528124357Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein3e-58223
NC_010516:2511035:251599025159902516346357Clostridium botulinum B1 str. Okra, complete genomehypothetical protein1e-57221
NC_010520:2585014:259052225905222590878357Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein2e-57220
NC_012914:469117:500661500661501011351Paenibacillus sp. JDR-2, complete genomehypothetical protein4e-1786.7
NC_011725:4870223:487192048719204872264345Bacillus cereus B4264 chromosome, complete genometransporter1e-1581.6
NC_015947:568124:580953580953581330378Burkholderia sp. JV3 chromosome, complete genomehypothetical protein2e-1581.3
NC_007503:919808:928671928671929111441Carboxydothermus hydrogenoformans Z-2901, complete genomemembrane protein, putaive2e-1271.2
NC_015578:247266:261890261890262258369Treponema primitia ZAS-2 chromosome, complete genometransporter2e-1270.9
NC_015422:704500:756802756802757167366Alicycliphilus denitrificans K601 chromosome, complete genomeputative small multi-drug resistant family protein1e-1168.6
NC_018870:1417851:143222314322231432546324Thermacetogenium phaeum DSM 12270 chromosome, complete genomehypothetical protein8e-1165.9
NC_012912:3853377:387828738782873878652366Dickeya zeae Ech1591, complete genomehypothetical protein1e-1065.1
NC_007796:2387002:238910023891002389456357Methanospirillum hungatei JF-1, complete genomeputative small multidrug resistance transmembrane protein4e-1063.5
NC_014650:304441:327943327943328311369Geobacillus sp. Y4.1MC1 chromosome, complete genomehypothetical protein6e-1062.8
NC_008702:369965:373681373681374046366Azoarcus sp. BH72, complete genomeputative Small Multi-Drug resistant family protein2e-0961.2
NC_013385:759420:774700774700775041342Ammonifex degensii KC4, complete genomeputative small multi-drug resistant family protein5e-0959.7
NC_013665:231023:241181241181241531351Methanocella paludicola SANAE, complete genomehypothetical protein5e-0856.6
NC_018419:1110000:112308111230811123461381Secondary endosymbiont of Ctenarytaina eucalypti chromosome,cation/cationic drug transporter5e-0856.6
NC_008553:1156285:116701411670141167250237Methanosaeta thermophila PT, complete genome3e-0754.3
NC_007644:2318855:232116623211662321504339Moorella thermoacetica ATCC 39073, complete genomeputative small multidrug resistance transmembrane protein1e-0652.4
NC_009484:2660048:266341226634122663771360Acidiphilium cryptum JF-5 chromosome, complete genomehypothetical protein2e-0650.8
NC_015677:896673:910446910446910802357Ramlibacter tataouinensis TTB310 chromosome, complete genomemembrane protein3e-0650.8