Pre_GI: BLASTP Hits

Some Help

Query: NC_012658:2498087:2500459 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 2500459, End: 2500713, Length: 255

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009697:2558286:255828625582862558540255Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein5e-41166
NC_010516:2305110:231104323110432311297255Clostridium botulinum B1 str. Okra, complete genomehypothetical protein1e-39161
NC_012563:2566500:256765425676542567908255Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein2e-39160
NC_017295:2022085:202315820231582023415258Clostridium acetobutylicum EA 2018 chromosome, complete genomehypothetical protein1e-1684.7
NC_003030:2023751:202375120237512024008258Clostridium acetobutylicum ATCC 824, complete genomeHypothetical protein, CF-8 family1e-1684.7
NC_015687:2025345:202534520253452025602258Clostridium acetobutylicum DSM 1731 chromosome, complete genomehypothetical protein1e-1684.7
NC_010674:2817651:282239028223902822626237Clostridium botulinum B str. Eklund 17B, complete genomehypothetical protein3e-1580.1
NC_009617:3926843:393273739327373932970234Clostridium beijerinckii NCIMB 8052 chromosome, complete genomehypothetical protein2e-1477.4