Pre_GI: BLASTP Hits

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Query: NC_012656:67949:91759 Bacillus anthracis str. A0248 plasmid pXO1, complete sequence

Start: 91759, End: 95427, Length: 3669

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012579:72715:9181591815954833669Bacillus anthracis str. CDC 684 plasmid pX01, complete sequencehypothetical protein02253
NC_007322:57710:9149591495951633669Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, completemembrane protein, putative, (pxo1-79)02253
NC_014331:57769:9179191791958074017Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, completemembrane protein02249
NC_017203:73952:8791487914919334020Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT281,hypothetical protein02140
NC_012473:46000:7876678766828034038Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequencehypothetical protein01937
NC_011655:88336:96369963691003493981Bacillus cereus AH187 plasmid pAH187_270, complete sequencehypothetical protein01827
NC_016792:143614:1516471516471556273981Bacillus cereus NC7401 plasmid pNCcld, complete sequencehypothetical protein01827
NC_005707:12735:2222622226262063981Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequencehypothetical protein01823
NC_011777:100631:1079971079971116713675Bacillus cereus AH820 plasmid pAH820_272, complete sequencehypothetical protein01689
NC_011775:156673:1654011654011700894689Bacillus cereus G9842 plasmid pG9842_209, complete sequencehypothetical protein8e-43176
NC_013792:109203:1216911216911244862796Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequenceouter membrane protein, putative8e-1583.6
NC_013792:109203:1196261196261216892064Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequencehypothetical protein1e-1276.3
NC_010381:35408:5596155961579011941Lysinibacillus sphaericus C3-41 plasmid pBsph, complete sequencehypothetical protein4e-0861.2