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Query: NC_012656:67949:88712 Bacillus anthracis str. A0248 plasmid pXO1, complete sequence

Start: 88712, End: 89626, Length: 915

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012579:72715:887688876889682915Bacillus anthracis str. CDC 684 plasmid pX01, complete sequencehypothetical protein1e-165582
NC_007322:57710:884488844889362915Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, completehypothetical protein1e-165582
NC_012473:46000:757287572876642915Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequencehypothetical protein2e-154545
NC_017203:73952:967689676897682915Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT281,hypothetical protein2e-152538
NC_011777:100631:104644104644105558915Bacillus cereus AH820 plasmid pAH820_272, complete sequencehypothetical protein9e-150529
NC_005707:12735:283392833929253915Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequencehypothetical protein2e-149528
NC_011655:88336:906439064391557915Bacillus cereus AH187 plasmid pAH187_270, complete sequencehypothetical protein1e-149528
NC_016792:143614:145921145921146835915Bacillus cereus NC7401 plasmid pNCcld, complete sequencehypothetical protein1e-149528
NC_014331:57769:889068890689658753Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, completemembrane protein1e-131469
NC_011775:156673:172262172262173167906Bacillus cereus G9842 plasmid pG9842_209, complete sequencehypothetical protein3e-48192
NC_013792:109203:126484126484127353870Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequencehypothetical protein1e-0861.2
NC_014964:2272413:228700622870062287614609Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completehypothetical protein1e-0757
NC_015520:2567329:258904625890462589777732Mahella australiensis 50-1 BON chromosome, complete genomehypothetical protein5e-0755.1
NC_014538:2158131:217568321756832176291609Thermoanaerobacter sp. X513 chromosome, complete genomehypothetical protein6e-0755.1
NC_010381:35408:502255022551148924Lysinibacillus sphaericus C3-41 plasmid pBsph, complete sequencehypothetical protein9e-0651.2