Pre_GI: BLASTP Hits

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Query: NC_012656:67949:78844 Bacillus anthracis str. A0248 plasmid pXO1, complete sequence

Start: 78844, End: 79968, Length: 1125

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014331:57769:7887578875799991125Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, completeputative nucleotidyltransferase0696
NC_012579:72715:7892778927800121086Bacillus anthracis str. CDC 684 plasmid pX01, complete sequencehypothetical protein0669
NC_007322:57710:7861978619797041086Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, completehypothetical protein0669
NC_012473:46000:6349063490645691080Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequencehypothetical protein1e-156553
NC_017316:2581781:2585470258547025865491080Enterococcus faecalis OG1RF chromosome, complete genomecell wall surface anchor family protein9e-1065.1
NC_004668:3053119:3055759305575930568351077Enterococcus faecalis V583, complete genomecell wall surface anchor family protein, putative9e-1064.7