Pre_GI: BLASTN Hits

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Query: NC_012654:237175 Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence

Start: 237175, End: 264096, Length: 26922

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010379:73718737189609922382Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence01376BLASTN svgBLASTP svg
NC_021182:10095261009526103309923574Clostridium pasteurianum BC1, complete genome4e-24121BLASTN svgBLASTP svg
NC_010418:70000700009209922100Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete4e-18101BLASTN svgBLASTP svg
NC_010379:11076011076013543724678Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence5e-1177.8BLASTN svgBLASTP svg
NC_009089:58165558165560656324909Clostridium difficile 630, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_021171:4367834*4367834439037922546Bacillus sp. 1NLA3E, complete genome8e-1073.8BLASTN svgBLASTP svg
NC_013895:35410*354105828922880Clostridiales genomosp. BVAB3 str. UPII9-5 chromosome, complete3e-0971.9BLASTN svgBLASTP svg
NC_012472:3661912*3661912368119019279Bacillus cereus 03BB102, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_008600:3643905*3643905366318919285Bacillus thuringiensis str. Al Hakam, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_003909:3587695*3587695360609918405Bacillus cereus ATCC 10987, complete genome1e-0869.9BLASTN svgBLASTP svg