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Query: NC_012654:18893 Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence

Start: 18893, End: 44557, Length: 25665

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010418:70000700009209922100Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete01467BLASTN svgBLASTP svg
NC_020291:684500*68450070271718218Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome1e-33153BLASTN svgBLASTP svg
NC_010723:485874*48587450809922226Clostridium botulinum E3 str. Alaska E43, complete genome2e-32149BLASTN svgBLASTP svg
NC_021182:4427468*4427468445021222745Clostridium pasteurianum BC1, complete genome9e-22113BLASTN svgBLASTP svg
NC_008262:2379144*2379144239845819315Clostridium perfringens SM101, complete genome1e-20109BLASTN svgBLASTP svg
NC_008261:2708929*2708929273260323675Clostridium perfringens ATCC 13124, complete genome1e-20109BLASTN svgBLASTP svg
NC_003366:24949072494907251858823682Clostridium perfringens str. 13, complete genome3e-18101BLASTN svgBLASTP svg
NC_010379:688068804619239313Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence2e-1695.6BLASTN svgBLASTP svg
NC_014909:219498*21949824042420927Candidatus Blochmannia vafer str. BVAF chromosome, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_013192:81585481585483809922246Leptotrichia buccalis DSM 1135, complete genome8e-1383.8BLASTN svgBLASTP svg
NC_003454:983681*983681100260518925Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete1e-1179.8BLASTN svgBLASTP svg
NC_014328:25889942588994260699318000Clostridium ljungdahlii ATCC 49587 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010418:13832513832516678028456Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete8e-1073.8BLASTN svgBLASTP svg
NC_001263:66266666266668995627291Deinococcus radiodurans R1 chromosome 1, complete sequence1e-0869.9BLASTN svgBLASTP svg
NC_003366:27882682788268280968621419Clostridium perfringens str. 13, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_008262:2649289*2649289270467655388Clostridium perfringens SM101, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_001263:13786051378605140253323929Deinococcus radiodurans R1 chromosome 1, complete sequence2e-0765.9BLASTN svgBLASTP svg
NC_003030:1097625*1097625112310625482Clostridium acetobutylicum ATCC 824, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_008530:469802*46980249214622345Lactobacillus gasseri ATCC 33323, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_010520:3837378*3837378385959922222Clostridium botulinum A3 str. Loch Maree, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_010674:192951*19295121941726467Clostridium botulinum B str. Eklund 17B, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_013406:6568273*6568273660155033278Paenibacillus sp. Y412MC10 chromosome, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_015687:1097447*1097447112292725481Clostridium acetobutylicum DSM 1731 chromosome, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_018704:896209*89620992081324605Amphibacillus xylanus NBRC 15112, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_019908:1296870*1296870131523618367Brachyspira pilosicoli P43/6/78 chromosome, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_018704:81733*8173311606034328Amphibacillus xylanus NBRC 15112, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_013721:82085282085284339322542Gardnerella vaginalis 409-05, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_009922:2721343*2721343276393542593Alkaliphilus oremlandii OhILAs, complete genome3e-0661.9BLASTN svgBLASTP svg