Pre_GI: BLASTP Hits

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Query: NC_012654:92487:97681 Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence

Start: 97681, End: 98664, Length: 984

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010418:138325:140259140259141242984Clostridium botulinum A3 str. Loch Maree plasmid pCLK, completeDNA polymerase III, delta subunit3e-145514
NC_010379:6880:103421034211325984Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequenceDNA polymerase III, delta subunit superfamily5e-145513
NC_008593:1704207:1723501172350117245231023Clostridium novyi NT, complete genomehypothetical protein3e-0859.7
NC_008600:4101748:4123960412396041249701011Bacillus thuringiensis str. Al Hakam, complete genomepossible DNA polymerase III, delta subunit9e-0858.2
NC_007530:4117071:4137069413706941380791011Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein9e-0858.2
NC_012472:4119192:4141404414140441424141011Bacillus cereus 03BB102, complete genomeDNA polymerase III, delta subunit9e-0858.2
NC_003997:4116944:4136942413694241379521011Bacillus anthracis str. Ames, complete genomehypothetical protein9e-0858.2
NC_012659:4116971:4136969413696941379791011Bacillus anthracis str. A0248, complete genomeDNA polymerase III subunit delta9e-0858.2
NC_010184:4155345:4175600417560041766101011Bacillus weihenstephanensis KBAB4, complete genomeDNA polymerase III, delta subunit8e-0858.2
NC_005957:4104880:4124877412487741258871011Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein1e-0757.8
NC_011772:4255161:4273852427385242748621011Bacillus cereus G9842, complete genomeDNA polymerase III, delta subunit3e-0756.2
NC_017208:4294341:4313051431305143140611011Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeDNA polymerase III subunit delta4e-0755.8
NC_014171:4178746:4197186419718641981961011Bacillus thuringiensis BMB171 chromosome, complete genomeDNA polymerase III subunit delta5e-0755.5
NC_011725:4288309:4307017430701743080271011Bacillus cereus B4264 chromosome, complete genomeDNA polymerase III subunit delta5e-0755.5
NC_004722:4244730:4263443426344342644531011Bacillus cereus ATCC 14579, complete genomehypothetical protein5e-0755.5
NC_011658:4107501:4129912412991241309221011Bacillus cereus AH187 chromosome, complete genomeDNA polymerase III subunit delta8e-0755.1