Pre_GI: BLASTP Hits

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Query: NC_012581:5052000:5067730 Bacillus anthracis str. CDC 684 chromosome, complete genome

Start: 5067730, End: 5068254, Length: 525

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016779:5009320:505938250593825059906525Bacillus cereus F837/76 chromosome, complete genomehypothetical protein2e-97354
NC_012472:5094009:510610851061085106632525Bacillus cereus 03BB102, complete genomehypothetical protein2e-97354
NC_008600:5046000:509368750936875094211525Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein2e-97354
NC_007530:5033095:506519850651985065722525Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein2e-97354
NC_003997:5032969:506507250650725065596525Bacillus anthracis str. Ames, complete genomehypothetical protein2e-97354
NC_005945:5053000:506640750664075066931525Bacillus anthracis str. Sterne, complete genomehypothetical protein2e-97354
NC_012659:5031827:506509850650985065622525Bacillus anthracis str. A0248, complete genomehypothetical protein2e-97354
NC_011773:5091609:512493751249375125461525Bacillus cereus AH820 chromosome, complete genomehypothetical protein4e-97353
NC_016771:5038435:505136650513665051890525Bacillus cereus NC7401, complete genomehypothetical protein8e-97352
NC_011969:4993386:504319550431955043719525Bacillus cereus Q1 chromosome, complete genomehypothetical protein8e-97352
NC_011658:5087887:509904350990435099567525Bacillus cereus AH187 chromosome, complete genomehypothetical protein8e-97352
NC_005957:5037499:507109850710985071622525Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein3e-96350
NC_003909:4996783:504448350444835045007525Bacillus cereus ATCC 10987, complete genomehypothetical protein4e-96349
NC_017200:5149528:518392951839295184453525Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein1e-95348
NC_014335:5005267:501860550186055019129525Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein2e-95347
NC_006274:5122500:513534351353435135867525Bacillus cereus E33L, complete genomehypothetical protein1e-94344
NC_014171:5107956:515626251562625156786525Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein1e-91335
NC_004722:5194000:524416252441625244686525Bacillus cereus ATCC 14579, complete genomehypothetical protein1e-91335
NC_011725:5201995:525165652516565252180525Bacillus cereus B4264 chromosome, complete genomehypothetical protein2e-91333
NC_017208:5305969:531876453187645319288525Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein6e-91332
NC_011772:5158680:520580352058035206327525Bacillus cereus G9842, complete genomehypothetical protein5e-91332
NC_010184:5085977:509962550996255100149525Bacillus weihenstephanensis KBAB4, complete genomehypothetical protein1e-86318
NC_009674:3903893:391628139162813916808528Bacillus cytotoxicus NVH 391-98 chromosome, complete genomehypothetical protein9e-83305
NC_010382:1020516:103681410368141037362549Lysinibacillus sphaericus C3-41, complete genomehypothetical protein3e-23107
NC_014829:4422314:442667744266774427207531Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeProtein of unknown function DUF25297e-1476.6