Pre_GI: BLASTP Hits

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Query: NC_012581:466798:473772 Bacillus anthracis str. CDC 684 chromosome, complete genome

Start: 473772, End: 474131, Length: 360

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:3724729:376458637645863764945360Bacillus anthracis str. A0248, complete genomehypothetical protein8e-66248
NC_011658:2080390:208289420828942083253360Bacillus cereus AH187 chromosome, complete genomehypothetical protein8e-66248
NC_003997:3724702:376455937645593764918360Bacillus anthracis str. Ames, complete genomehypothetical protein8e-66248
NC_005945:3747652:376505937650593765418360Bacillus anthracis str. Sterne, complete genomehypothetical protein8e-66248
NC_007530:3749645:376468637646863765045360Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein8e-66248
NC_016771:2039195:204172020417202042058339Bacillus cereus NC7401, complete genomehypothetical protein2e-61234
NC_011773:4141765:415656741565674156941375Bacillus cereus AH820 chromosome, complete genomehypothetical protein9e-22102
NC_009674:2678932:269248126924812692840360Bacillus cytotoxicus NVH 391-98 chromosome, complete genomehypothetical protein4e-1683.2
NC_015690:1186545:121822812182281218587360Paenibacillus mucilaginosus KNP414 chromosome, complete genomephage protein2e-1167.8
NC_016935:1636278:166774316677431668048306Paenibacillus mucilaginosus 3016 chromosome, complete genomephage protein5e-1166.6
NC_014393:937000:966920966920967249330Clostridium cellulovorans 743B chromosome, complete genomehypothetical protein7e-0959.3
NC_012563:2101449:211534921153492115705357Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein2e-0754.7
NC_013411:597235:620486620486620809324Geobacillus sp. Y412MC61, complete genomehypothetical protein4e-0753.5
NC_014915:2963500:298312629831262983449324Geobacillus sp. Y412MC52 chromosome, complete genomehypothetical protein4e-0753.5
NC_012563:2925472:293970329397032940059357Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein5e-0753.1
NC_014328:303063:373393373393373716324Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein1e-0652
NC_009699:2017329:202668920266892027045357Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein1e-0652
NC_017297:2017000:202679520267952027151357Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein1e-0652
NC_010520:1614333:164398016439801644336357Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein1e-0652
NC_020291:1122282:113198611319861132336351Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehypothetical protein DUF31683e-0650.4
NC_017295:2022085:203684520368452037168324Clostridium acetobutylicum EA 2018 chromosome, complete genomehypothetical protein4e-0650.4
NC_003030:2023751:203743820374382037761324Clostridium acetobutylicum ATCC 824, complete genomehypothetical protein4e-0650.4
NC_015687:2025345:203903220390322039355324Clostridium acetobutylicum DSM 1731 chromosome, complete genomehypothetical protein4e-0650.4
NC_014479:1961692:197126519712651971642378Bacillus subtilis subsp. spizizenii str. W23 chromosome, completehypothetical protein5e-0650.1