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Query: NC_012581:466798:473338 Bacillus anthracis str. CDC 684 chromosome, complete genome

Start: 473338, End: 473775, Length: 438

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:3724729:376494237649423765379438Bacillus anthracis str. A0248, complete genomehypothetical protein5e-81298
NC_005945:3747652:376541537654153765852438Bacillus anthracis str. Sterne, complete genomehypothetical protein5e-81298
NC_007530:3749645:376504237650423765479438Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein5e-81298
NC_003997:3724702:376491537649153765352438Bacillus anthracis str. Ames, complete genomehypothetical protein5e-81298
NC_011658:2080390:208246020824602082897438Bacillus cereus AH187 chromosome, complete genomehypothetical protein1e-79294
NC_016771:2039195:204126520412652041702438Bacillus cereus NC7401, complete genomehypothetical protein1e-79294
NC_011773:4141765:415693841569384157372435Bacillus cereus AH820 chromosome, complete genomephage protein, HK97 gp10 family1e-32138
NC_009674:2678932:269283726928372693271435Bacillus cytotoxicus NVH 391-98 chromosome, complete genomeHK97 family phage protein3e-24110
NC_016935:1636278:166730016673001667689390Paenibacillus mucilaginosus 3016 chromosome, complete genomeHK97 family phage protein2e-1477.8
NC_015690:1186545:121784812178481218231384Paenibacillus mucilaginosus KNP414 chromosome, complete genomeHK97 family phage protein3e-1477.4
NC_014393:937000:966531966531966923393Clostridium cellulovorans 743B chromosome, complete genomephage protein, HK97 gp10 family2e-1064.3
NC_008261:1787345:180065718006571801085429Clostridium perfringens ATCC 13124, complete genomephage protein, HK97 gp10 family2e-0961.6
NC_021184:4493440:450339245033924503763372Desulfotomaculum gibsoniae DSM 7213, complete genomephage protein, HK97 gp10 family3e-0857
NC_014328:303063:373016373016373396381Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative phage-like protein4e-0857
NC_014479:1961692:197163919716391972022384Bacillus subtilis subsp. spizizenii str. W23 chromosome, completehypothetical protein4e-0753.5
NC_010516:2676746:269014126901412690530390Clostridium botulinum B1 str. Okra, complete genomephage protein, HK97 gp10 family4e-0753.5
NC_014624:1235818:125467512546751255163489Eubacterium limosum KIST612 chromosome, complete genomeHK97 family phage protein5e-0753.1
NC_009697:2558286:257165425716542572028375Clostridium botulinum A str. ATCC 19397 chromosome, completeHK97 family phage protein1e-0652
NC_017297:3428429:344202434420243442407384Clostridium botulinum F str. 230613 chromosome, complete genomephage protein, HK97 gp10 family1e-0651.6
NC_009699:3429817:344341134434113443794384Clostridium botulinum F str. Langeland chromosome, complete genomeHK97 family phage protein1e-0651.6
NC_009697:3110772:312127331212733121647375Clostridium botulinum A str. ATCC 19397 chromosome, completeHK97 family phage protein2e-0651.2
NC_014624:2878457:287881228788122879303492Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein3e-0650.8