Some Help

Query: NC_012581:4478036:4494805 Bacillus anthracis str. CDC 684 chromosome, complete genome

Start: 4494805, End: 4495116, Length: 312

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4474000:449328144932814493592312Bacillus anthracis str. A0248, complete genomehypothetical protein9e-43171
NC_003997:4473973:449325444932544493565312Bacillus anthracis str. Ames, complete genomehypothetical protein9e-43171
NC_007530:4474000:449338144933814493692312Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein9e-43171
NC_005957:4472800:448833244883324488643312Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein5e-42169
NC_011773:4541306:455676045567604557071312Bacillus cereus AH820 chromosome, complete genomehypothetical protein5e-42169
NC_011969:4396000:441570844157084416019312Bacillus cereus Q1 chromosome, complete genomehypothetical protein5e-42169
NC_017208:4662500:467783446778344678145312Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein1e-41167
NC_011772:4606000:462280446228044623115312Bacillus cereus G9842, complete genomehypothetical protein1e-41167
NC_014335:4414052:442724644272464427557312Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein2e-41167
NC_010184:4497473:451801845180184518329312Bacillus weihenstephanensis KBAB4, complete genomePropeptide PepSY amd peptidase M47e-41165