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Query: NC_012581:4478036:4492832 Bacillus anthracis str. CDC 684 chromosome, complete genome

Start: 4492832, End: 4493341, Length: 510

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4474000:449130844913084491817510Bacillus anthracis str. A0248, complete genomeNTPase1e-94344
NC_005945:4473790:449197044919704492479510Bacillus anthracis str. Sterne, complete genomehypothetical protein1e-94344
NC_003997:4473973:449128144912814491790510Bacillus anthracis str. Ames, complete genomehypothetical protein1e-94344
NC_007530:4474000:449140844914084491917510Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein1e-94344
NC_014335:4414052:442523344252334425742510Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein4e-94343
NC_005957:4472800:448636044863604486869510Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein2e-92337
NC_011969:4396000:441369644136964414205510Bacillus cereus Q1 chromosome, complete genomentpase1e-92337
NC_017200:4484399:450155645015564502065510Bacillus thuringiensis serovar finitimus YBT-020 chromosome,NTPase1e-92337
NC_011773:4541306:455478845547884555297510Bacillus cereus AH820 chromosome, complete genomeNTPase7e-92335
NC_017208:4662500:467582046758204676329510Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeNTPase2e-91334
NC_011725:4636521:465494146549414655450510Bacillus cereus B4264 chromosome, complete genomeNTPase3e-90330
NC_011772:4606000:462079046207904621299510Bacillus cereus G9842, complete genomehypothetical protein2e-90330
NC_010184:4497473:451599745159974516506510Bacillus weihenstephanensis KBAB4, complete genomeprotein of unknown function DUF842e-88323
NC_004722:4614442:463066846306684631132465Bacillus cereus ATCC 14579, complete genomehypothetical protein1e-82304
NC_011961:304158:342390342390342971582Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequenceNTPase2e-1891.7
NC_009376:769199:772837772837773370534Pyrobaculum arsenaticum DSM 13514 chromosome, complete genomehypothetical protein2e-1478.6
NC_008698:1556223:157655015765501577095546Thermofilum pendens Hrk 5, complete genomeprotein of unknown function DUF845e-1477
NC_015320:1690047:169051316905131691034522Archaeoglobus veneficus SNP6 chromosome, complete genomehypothetical protein3e-1374.3
NC_008701:1259000:126204212620421262575534Pyrobaculum islandicum DSM 4184, complete genomeprotein of unknown function DUF844e-1373.9
NC_013926:829665:849528849528850490963Aciduliprofundum boonei T469 chromosome, complete genomecytidyltransferase-related domain protein2e-1271.2
NC_015562:785959:805096805096805824729Methanotorris igneus Kol 5 chromosome, complete genomehypothetical protein5e-0960.5
NC_012779:610509:612849612849613385537Edwardsiella ictaluri 93-146, complete genomehypothetical protein3e-0651.6