Pre_GI: BLASTP Hits

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Query: NC_012581:4478036:4484788 Bacillus anthracis str. CDC 684 chromosome, complete genome

Start: 4484788, End: 4485906, Length: 1119

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4474000:4483291448329144844091119Bacillus anthracis str. A0248, complete genomenicotinate phosphoribosyltransferase0766
NC_003997:4473973:4483264448326444843821119Bacillus anthracis str. Ames, complete genomenicotinate phosphoribosyltransferase0766
NC_007530:4474000:4483391448339144845091119Bacillus anthracis str. 'Ames Ancestor', complete genomenicotinate phosphoribosyltransferase0766
NC_005945:4473790:4483953448395344850711119Bacillus anthracis str. Sterne, complete genomenicotinate phosphoribosyltransferase0766
NC_011969:4396000:4405800440580044069181119Bacillus cereus Q1 chromosome, complete genomenicotinate phosphoribosyltransferase0764
NC_005957:4472800:4478385447838544795031119Bacillus thuringiensis serovar konkukian str. 97-27, completenicotinate phosphoribosyltransferase0764
NC_014335:4414052:4417363441736344184811119Bacillus cereus biovar anthracis str. CI chromosome, completenicotinate phosphoribosyltransferase0764
NC_004722:4614442:4621657462165746227751119Bacillus cereus ATCC 14579, complete genomenicotinate phosphoribosyltransferase0763
NC_011725:4636521:4646022464602246471401119Bacillus cereus B4264 chromosome, complete genomenicotinate phosphoribosyltransferase0763
NC_017200:4484399:4492995449299544941131119Bacillus thuringiensis serovar finitimus YBT-020 chromosome,nicotinate phosphoribosyltransferase0763
NC_011773:4541306:4546894454689445480121119Bacillus cereus AH820 chromosome, complete genomenicotinate phosphoribosyltransferase0761
NC_017208:4662500:4667081466708146681991119Bacillus thuringiensis serovar chinensis CT-43 chromosome, completenicotinate phosphoribosyltransferase0761
NC_011772:4606000:4611916461191646130341119Bacillus cereus G9842, complete genomehypothetical protein0761
NC_010184:4497473:4507093450709345082111119Bacillus weihenstephanensis KBAB4, complete genomenicotinate phosphoribosyltransferase0746
NC_014448:414784:4318924318924328991008Mycoplasma hyorhinis HUB-1 chromosome, complete genomeNicotinate phosphoribosyltransferase8e-76284
NC_016829:308000:3113643113643123711008Mycoplasma hyorhinis GDL-1 chromosome, complete genomenicotinic acid phosphoribosyltransferase6e-75281
NC_017519:37158:4407244072450791008Mycoplasma hyorhinis MCLD chromosome, complete genomenicotinate phosphoribosyltransferase6e-75281
NC_015725:743567:7448797448797458801002Mycoplasma bovis Hubei-1 chromosome, complete genomenicotinate phosphoribosyltransferase7e-73274
NC_010003:1444623:1450373145037314516831311Petrotoga mobilis SJ95, complete genomenicotinic acid phosphoribosyltransferase-like protein1e-51203
NC_014654:1548194:1548194154819415495221329Halanaerobium sp. 'sapolanicus' chromosome, complete genomeQuinolinate phosphoribosyl transferase2e-35150
NC_015931:1653604:1665327166532716665201194Pyrolobus fumarii 1A, complete genomeNicotinate phosphoribosyltransferase1e-30134
NC_012883:104987:1291471291471303191173Thermococcus sibiricus MM 739, complete genomenicotinate phosphoribosyltransferase7e-28125
NC_008818:1127575:1138141113814111393221182Hyperthermus butylicus DSM 5456, complete genomepredicted Nicotinic acid phosphoribosyltransferase6e-27122
NC_012804:348235:3602843602843614561173Thermococcus gammatolerans EJ3, complete genomeNicotinate-nucleotide pyrophosphorylase (nadC)8e-26118
NC_011295:929293:9519679519679531541188Coprothermobacter proteolyticus DSM 5265, complete genomenicotinate phosphoribosyltransferase3e-25116
NC_013939:1902397:1921563192156319227321170Deferribacter desulfuricans SSM1, complete genomenicotinate phosphoribosyltransferase4e-25115
NC_009440:1568500:1569587156958715707531167Metallosphaera sedula DSM 5348 chromosome, complete genomenicotinate phosphoribosyltransferase5e-25115
NC_015435:537483:5493915493915505511161Metallosphaera cuprina Ar-4 chromosome, complete genomenicotinate phosphoribosyltransferase1e-24114
NC_007643:791500:8078398078398090711233Rhodospirillum rubrum ATCC 11170, complete genomehypothetical protein8e-24111
NC_012623:929080:9435399435399447021164Sulfolobus islandicus Y.N.15.51 chromosome, complete genomenicotinate phosphoribosyltransferase2e-23110
NC_012588:1619376:1623916162391616250791164Sulfolobus islandicus M.14.25 chromosome, complete genomenicotinate phosphoribosyltransferase2e-23110
NC_012589:1723897:1727788172778817289511164Sulfolobus islandicus L.S.2.15, complete genomeQuinolinate phosphoribosyl transferase2e-23110
NC_012622:1679812:1681921168192116830841164Sulfolobus islandicus Y.G.57.14 chromosome, complete genomenicotinate phosphoribosyltransferase2e-23110
NC_013769:1739363:1743079174307917442421164Sulfolobus islandicus L.D.8.5 chromosome, complete genomequinolinate phosphoribosyl transferase2e-23110
NC_017275:1669587:1674127167412716752901164Sulfolobus islandicus HVE10/4 chromosome, complete genomequinolinate phosphoribosyl transferase2e-23110
NC_017276:1525102:1529642152964215308051164Sulfolobus islandicus REY15A chromosome, complete genomequinolinate phosphoribosyl transferase2e-23110
NC_012632:1745921:1749812174981217509751164Sulfolobus islandicus M.16.27 chromosome, complete genomenicotinate phosphoribosyltransferase2e-23110
NC_012726:1646330:1650046165004616512091164Sulfolobus islandicus M.16.4 chromosome, complete genomenicotinate phosphoribosyltransferase2e-23110
NC_015518:1160430:1162537116253711636971161Acidianus hospitalis W1 chromosome, complete genomeQuinolinate phosphoribosyl transferase1e-21104
NC_002754:285759:3015773015773027401164Sulfolobus solfataricus P2, complete genomenicotinate phosphoribosyltransferase2e-21103
NC_007181:1238806:1251589125158912527611173Sulfolobus acidocaldarius DSM 639, complete genomenicotinate phosphoribosyltransferase4e-21102
NC_008343:1548020:1576554157655415776931140Granulibacter bethesdensis CGDNIH1, complete genomenicotinate phosphoribosyltransferase3e-2099.8
NC_003106:1367404:1381152138115213823211170Sulfolobus tokodaii str. 7, complete genomenicotinate phosphoribosyltransferase4e-2099.4
NC_009051:1074993:1078834107883410799581125Methanoculleus marisnigri JR1, complete genomeQuinolinate phosphoribosyl transferase9e-1994.7
NC_019962:3331849:3354630335463033557931164Natrinema pellirubrum DSM 15624, complete genomenicotinic acid phosphoribosyltransferase2e-1894
NC_014374:1072218:1147420114742011486281209Acidilobus saccharovorans 345-15 chromosome, complete genomeNicotinic acid phosphoribosyltransferase, putative8e-1685.1
NC_016627:1133759:1150184115018411516261443Clostridium clariflavum DSM 19732 chromosome, complete genomeputative nicotinate phosphoribosyltransferase8e-1684.7
NC_015930:821342:8386188386188400811464Lactococcus garvieae ATCC 49156, complete genomenicotinate phosphoribosyltransferase9e-1684.7
NC_009446:174951:2102542102542117021449Dichelobacter nodosus VCS1703A, complete genomenicotinate phosphoribosyltransferase1e-1584.3
NC_008212:61567:7729077290784501161Haloquadratum walsbyi DSM 16790, complete genomenicotinate phosphoribosyltransferase2e-1583.6
NC_009495:1516000:1537174153717415386551482Clostridium botulinum A str. ATCC 3502 chromosome, complete genomenicotinate phosphoribosyltransferase2e-1583.6
NC_013504:1388480:1405788140578814072181431Lactobacillus johnsonii FI9785 chromosome, complete genomehypothetical protein1e-1481.3
NC_015161:792955:7956117956117970861476Deinococcus proteolyticus MRP chromosome, complete genomenicotinate phosphoribosyltransferase9e-1581.3
NC_007929:1290568:1291415129141512928811467Lactobacillus salivarius subsp. salivarius UCC118, complete genomeNicotinate phosphoribosyltransferase2e-1377.4
NC_009513:169146:1885131885131899461434Lactobacillus reuteri F275, complete genomenicotinate phosphoribosyltransferase2e-1377
NC_008525:1493317:1494153149415314956161464Pediococcus pentosaceus ATCC 25745, complete genomeNicotinic acid phosphoribosyltransferase5e-1375.5
NC_006322:3198829:3213067321306732145361470Bacillus licheniformis ATCC 14580, complete genomenicotinate phosphoribosyltransferase3e-1272.8
NC_015978:412856:4321684321684336341467Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completeNicotinate phosphoribosyltransferase8e-1271.6
NC_009714:74500:9603596035974651431Campylobacter hominis ATCC BAA-381, complete genomeputative nicotinate phosphoribosyltransferase1e-1171.2
NC_017347:2017097:2036503203650320379721470Staphylococcus aureus subsp. aureus T0131 chromosome, completeNicotinate phosphoribosyltransferase7e-1168.6
NC_004193:375416:375416375416675301299886Oceanobacillus iheyensis HTE831, complete genome1e-1068.2
NC_016023:1658377:1662004166200416634701467Bacillus coagulans 36D1 chromosome, complete genomenicotinate phosphoribosyltransferase1e-1067.8
NC_015634:2779392:2798034279803427995001467Bacillus coagulans 2-6 chromosome, complete genomenicotinate phosphoribosyltransferase1e-1067.8
NC_004193:375416:4093884093884108511464Oceanobacillus iheyensis HTE831, complete genomenicotinate phosphoribosyltransferase7e-1065.1
NC_010545:1691999:1717667171766717190521386Corynebacterium urealyticum DSM 7109, complete genomeputative nicotinic acid phosphoribosyltransferase1e-0861.2
NC_008529:264000:2672542672542686871434Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365, completeNicotinic acid phosphoribosyltransferase2e-0860.8
NC_018720:457289:4572894572894586351347Bifidobacterium asteroides PRL2011 chromosome, complete genomenicotinate phosphoribosyltransferase2e-0757.4
NC_013730:778076:7934887934887950051518Spirosoma linguale DSM 74, complete genomenicotinate phosphoribosyltransferase4e-0652.8
NC_013174:923737:9443049443049456351332Jonesia denitrificans DSM 20603, complete genomenicotinate phosphoribosyltransferase8e-0651.6