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Query: NC_012581:1505276:1516443 Bacillus anthracis str. CDC 684 chromosome, complete genome

Start: 1516443, End: 1517600, Length: 1158

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008528:331260:3362393362393374021164Oenococcus oeni PSU-1, complete genomeAcetyltransferase7e-30131
NC_017208:2942554:2948692294869229498491158Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeacetyltransferase0709
NC_014729:703000:7255697255697267771209Halogeometricum borinquense DSM 11551 chromosome, complete genomeacetyltransferase6e-29128
NC_005945:2716000:2721425272142527225971173Bacillus anthracis str. Sterne, complete genomeacetyltransferase, GNAT family0765
NC_014335:2718000:2723583272358327247401158Bacillus cereus biovar anthracis str. CI chromosome, completeacetyltransferase, GNAT family0759
NC_008600:2792584:2796828279682827979851158Bacillus thuringiensis str. Al Hakam, complete genomeacetyltransferase, GNAT family0730
NC_007530:2716885:2721090272109027222471158Bacillus anthracis str. 'Ames Ancestor', complete genomeacetyltransferase, gnat family0764
NC_005957:2756000:2760364276036427615361173Bacillus thuringiensis serovar konkukian str. 97-27, completeacetyltransferase, GNAT family0741
NC_003997:2715623:2720962272096227221191158Bacillus anthracis str. Ames, complete genomeacetyltransferase, GNAT family0764
NC_003909:2798622:2802776280277628039331158Bacillus cereus ATCC 10987, complete genomeacetyltransferase, GNAT family0709
NC_012659:2715651:2720990272099027221471158Bacillus anthracis str. A0248, complete genomeacetyltransferase, GNAT family0764
NC_006274:2779380:2784911278491127860681158Bacillus cereus E33L, complete genomeacetyltransferase, GNAT family0719
NC_011772:2860000:2866427286642728675871161Bacillus cereus G9842, complete genomeacetyltransferase, GNAT family0703
NC_012225:787737:8100668100668113461281Brachyspira hyodysenteriae WA1, complete genomeEis, Predicted acetyltransferase-like acetyltransferase6e-52205
NC_013947:5682895:5682895568289556841331239Stackebrandtia nassauensis DSM 44728 chromosome, complete genomeGCN5-related N-acetyltransferase4e-1582.8
NC_013520:1860286:1875641187564118768341194Veillonella parvula DSM 2008, complete genomeGCN5-related N-acetyltransferase4e-21102
NC_020291:1045058:1064923106492310661611239Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeGCN5-related N-acetyltransferase8e-54211
NC_011969:2706000:2711505271150527126621158Bacillus cereus Q1 chromosome, complete genomeGNAT family acetyltransferase0706
NC_011773:2782465:2786672278667227878291158Bacillus cereus AH820 chromosome, complete genomeGNAT family acetyltransferase0750
NC_016779:2693790:2698034269803426991911158Bacillus cereus F837/76 chromosome, complete genomeGNAT family acetyltransferase0755
NC_007576:299266:299266299266300150885Lactobacillus sakei subsp. sakei 23K, complete genomehypothetical protein2e-22107
NC_019673:1420198:1423452142345214247351284Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein2e-0654.3