Pre_GI: BLASTN Hits

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Query: NC_012579:1 Bacillus anthracis str. CDC 684 plasmid pX01, complete sequence

Start: 1, End: 22099, Length: 22099

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_007322:112209922099Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, complete019660BLASTN svgBLASTP svg
NC_007322:57710577109516337454Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, complete1e-72281BLASTN svgBLASTP svg
NC_012473:46000460008500439005Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequence7e-84319BLASTN svgBLASTP svg
NC_014331:57769*577699580738039Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, complete4e-70274BLASTN svgBLASTP svg
NC_014331:112209922099Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, complete015250BLASTN svgBLASTP svg
NC_011775:23354233544318519832Bacillus cereus G9842 plasmid pG9842_209, complete sequence3e-30141BLASTN svgBLASTP svg
NC_010418:70000700009209922100Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete4e-0867.9BLASTN svgBLASTP svg