Pre_GI: BLASTP Hits

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Query: NC_012579:72715:88417 Bacillus anthracis str. CDC 684 plasmid pX01, complete sequence

Start: 88417, End: 88767, Length: 351

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012656:67949:883618836188711351Bacillus anthracis str. A0248 plasmid pXO1, complete sequencepXO1-755e-54209
NC_014331:57769:884048840488754351Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, completehypothetical protein5e-54209
NC_007322:57710:880978809788447351Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, completehypothetical protein5e-54209
NC_017203:73952:976839768398033351Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT281,hypothetical protein5e-52202
NC_012473:46000:753777537775727351Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequencehypothetical protein5e-51199
NC_005707:12735:292542925429604351Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequencehypothetical protein7e-50195
NC_011655:88336:902929029290642351Bacillus cereus AH187 plasmid pAH187_270, complete sequencehypothetical protein7e-50195
NC_011777:100631:104293104293104643351Bacillus cereus AH820 plasmid pAH820_272, complete sequencehypothetical protein7e-50195
NC_016792:143614:145570145570145920351Bacillus cereus NC7401 plasmid pNCcld, complete sequencehypothetical protein7e-50195
NC_011775:156673:173181173181173507327Bacillus cereus G9842 plasmid pG9842_209, complete sequencehypothetical protein2e-1374.3