Pre_GI: BLASTP Hits

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Query: NC_012563:4101000:4121844 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 4121844, End: 4122653, Length: 810

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:3939328:395949739594973960306810Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein8e-149526
NC_009699:3940984:396180239618023962611810Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein8e-149526
NC_009698:3706154:372696837269683727777810Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein8e-149526
NC_009697:3809044:382985838298583830667810Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein8e-149526
NC_009495:3832500:385332438533243854133810Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein8e-149526
NC_010520:3938490:395931739593173960126810Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein8e-149526
NC_010516:3903867:392467739246773925486810Clostridium botulinum B1 str. Okra, complete genomehypothetical protein8e-149526
NC_012658:3923546:394437939443793945188810Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein2e-148524
NC_014328:4546390:456506045650604565875816Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative ATP/GTP-binding protein3e-106384
NC_004557:81362:813628136282177816Clostridium tetani E88, complete genomehypothetical protein3e-105381
NC_008262:67711:841528415284952801Clostridium perfringens SM101, complete genomehypothetical protein1e-93342
NC_003366:2556457:256989825698982570698801Clostridium perfringens str. 13, complete genomehypothetical protein3e-93341
NC_020291:6216000:622888162288816229693813Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehypothetical protein5e-87320
NC_010723:3530000:356882235688223569640819Clostridium botulinum E3 str. Alaska E43, complete genomeprotein YqfL9e-86316
NC_010674:3674739:371179637117963712614819Clostridium botulinum B str. Eklund 17B, complete genomeprotein YqfL4e-84311
NC_007907:3472494:348720534872053488026822Desulfitobacterium hafniense Y51, complete genomehypothetical protein1e-53209
NC_007644:626992:629855629855630739885Moorella thermoacetica ATCC 39073, complete genomeProtein of unknown function DUF2994e-51201
NC_006270:2591317:261037726103772611189813Bacillus licheniformis ATCC 14580, complete genomehypothetical protein7e-51201
NC_006322:2592176:261123626112362612048813Bacillus licheniformis ATCC 14580, complete genomehypothetical protein7e-51201
NC_013198:1538792:157170715717071572537831Lactobacillus rhamnosus GG, complete genomephosphotransferase1e-46186
NC_007168:454000:462645462645463475831Staphylococcus haemolyticus JCSC1435, complete genomehypothetical protein2e-40166
NC_013939:492959:506775506775507626852Deferribacter desulfuricans SSM1, complete genomehypothetical protein7e-37154
NC_013943:2431643:243562124356212436430810Denitrovibrio acetiphilus DSM 12809 chromosome, complete genomehypothetical protein4e-35148
NC_013171:342714:380026380026380856831Anaerococcus prevotii DSM 20548, complete genomeprotein of unknown function DUF2999e-35147
NC_008346:410940:412896412896413726831Syntrophomonas wolfei subsp. wolfei str. Goettingen, completehypothetical protein2e-34145
NC_006833:806467:825671825671826489819Wolbachia endosymbiont strain TRS of Brugia malayi, completehypothetical protein5e-29128
NC_012108:2194251:221125922112592212242984Desulfobacterium autotrophicum HRM2, complete genomehypothetical protein5e-29128
NC_007797:1016456:102355910235591024401843Anaplasma phagocytophilum HZ, complete genomehypothetical protein2e-28125
NC_007798:260324:266964266964267776813Neorickettsia sennetsu str. Miyayama, complete genomehypothetical protein3e-22105
NC_013009:270000:278157278157278969813Neorickettsia risticii str. Illinois, complete genomehypothetical protein5e-22104
NC_015381:2859000:292610529261052926920816Burkholderia gladioli BSR3 chromosome 1, complete sequencehypothetical protein9e-21100
NC_012560:2315350:232233423223342323152819Azotobacter vinelandii DJ, complete genomehypothetical protein4e-1685.5
NC_021150:2315362:232234623223462323164819Azotobacter vinelandii CA6, complete genomehypothetical protein4e-1685.5
NC_008228:2068641:208192420819242082736813Pseudoalteromonas atlantica T6c, complete genomeprotein of unknown function DUF2995e-1581.6
NC_011901:3072817:307281730728173073716900Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, completehypothetical protein6e-1478.2
NC_007482:607365:629179629179629988810Pseudoalteromonas haloplanktis TAC125 chromosome II, completehypothetical protein6e-1478.2
NC_012691:2050957:205956620595662060387822Tolumonas auensis DSM 9187, complete genomeprotein of unknown function DUF2996e-1478.2
NC_015850:2451957:245654424565442457386843Acidithiobacillus caldus SM-1 chromosome, complete genomehypothetical protein3e-1375.9