Pre_GI: BLASTP Hits

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Query: NC_012563:3921859:3939477 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 3939477, End: 3940325, Length: 849

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:3744000:376248937624893763337849Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein4e-136484
NC_009698:3526359:354467135446713545519849Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein4e-136484
NC_009697:3629250:364756236475623648410849Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein4e-136484
NC_010520:3753875:377214037721403772988849Clostridium botulinum A3 str. Loch Maree, complete genomeconserved hypothetical protein TIGR001594e-136484
NC_017297:3752000:377301937730193773867849Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein1e-135482
NC_009699:3753599:377440537744053775253849Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein1e-135482
NC_010516:3724312:374262637426263743474849Clostridium botulinum B1 str. Okra, complete genomeconserved hypothetical protein TIGR001592e-135481
NC_014328:4387303:440190144019014402737837Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein1e-98359
NC_008261:2920999:293312529331252933982858Clostridium perfringens ATCC 13124, complete genomeconserved hypothetical protein TIGR001591e-81302
NC_014614:554949:575567575567576382816Clostridium sticklandii, complete genomehypothetical protein2e-61235
NC_009922:2590317:259337125933712594198828Alkaliphilus oremlandii OhILAs, complete genomeprotein of unknown function DUF1476e-61234
NC_009089:117980:153933153933154772840Clostridium difficile 630, complete genomehypothetical protein6e-59227
NC_013316:120759:149443149443150282840Clostridium difficile R20291, complete genomehypothetical protein6e-59227
NC_015555:386000:390896390896391729834Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeConserved hypothetical protein CHP001592e-58226
NC_015958:2206032:223762722376272238460834Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomehypothetical protein3e-58225
NC_012034:390273:414233414233415090858Anaerocellum thermophilum DSM 6725, complete genomeprotein of unknown function DUF1474e-58224
NC_014538:1942500:195706319570631957896834Thermoanaerobacter sp. X513 chromosome, complete genomehypothetical protein1e-57223
NC_013171:416279:418569418569419396828Anaerococcus prevotii DSM 20548, complete genomeprotein of unknown function DUF1475e-56218
NC_014551:199500:201029201029201850822Bacillus amyloliquefaciens DSM 7, complete genomehypothetical protein1e-53210
NC_014829:178000:187566187566188396831Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeprotein of unknown function DUF1472e-53209
NC_017190:182449:183818183818184639822Bacillus amyloliquefaciens LL3 chromosome, complete genomehypothetical protein1e-53209
NC_020272:3706722:372629637262963727117822Bacillus amyloliquefaciens IT-45, complete genomehypothetical protein1e-53209
NC_020410:198000:200113200113200934822Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completeputative enzyme with DAC domain protein / ABC transporter, permease protein YbbP clustered with maltose/maltodextrin transporter / Tlr1762 protein1e-53209
NC_009725:200071:200071200071200892822Bacillus amyloliquefaciens FZB42, complete genomeYbbP1e-53209
NC_017188:177500:179008179008179829822Bacillus amyloliquefaciens TA208 chromosome, complete genomehypothetical protein1e-53209
NC_017191:183500:184918184918185739822Bacillus amyloliquefaciens XH7 chromosome, complete genomehypothetical protein1e-53209
NC_018665:139646:155317155317156177861Exiguobacterium antarcticum B7 chromosome, complete genomeHypothetical protein8e-52204
NC_010556:141374:155371155371156231861Exiguobacterium sibiricum 255-15, complete genomeprotein of unknown function DUF1476e-52204
UCMB5137:3857960:385876338587633859584822Bacillus atrophaeus UCMB-5137hypothetical protein4e-52204
NC_011567:139598:153124153124153999876Anoxybacillus flavithermus WK1, complete genomehypothetical protein4e-52204
NC_015565:287900:289879289879290703825Desulfotomaculum carboxydivorans CO-1-SRB chromosome, completehypothetical protein4e-52204
NC_015589:366296:366296366296367120825Desulfotomaculum ruminis DSM 2154 chromosome, complete genomehypothetical protein1e-51203
NC_011830:923424:925076925076925891816Desulfitobacterium hafniense DCB-2, complete genomeprotein of unknown function DUF1471e-51203
NC_012673:1540000:154558815455881546448861Exiguobacterium sp. AT1b, complete genomeprotein of unknown function DUF1471e-51203
NC_019897:329945:347846347846348682837Thermobacillus composti KWC4 chromosome, complete genomehypothetical protein4e-51201
NC_021184:592501:595992595992596828837Desulfotomaculum gibsoniae DSM 7213, complete genomeTIGR00159 family protein9e-51200
NC_010718:237962:248942248942249760819Natranaerobius thermophilus JW/NM-WN-LF, complete genomeprotein of unknown function DUF1471e-50200
NC_017208:108134:162977162977163798822Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein1e-48193
NC_014171:109280:161214161214162035822Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein1e-48193
NC_007498:1148249:117253711725371173322786Pelobacter carbinolicus DSM 2380, complete genomeconserved hypothetical protein TIGR001592e-46186
NC_004193:241480:251957251957252778822Oceanobacillus iheyensis HTE831, complete genomehypothetical protein2e-45182
NC_017341:2303005:231861223186122319421810Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,checkpoint controller nucleotide-binding protein2e-45182
NC_002951:2208813:222441822244182225227810Staphylococcus aureus subsp. aureus COL, complete genomehypothetical protein2e-45182
NC_012004:1053682:106331510633151064160846Streptococcus uberis 0140J, complete genomemembrane protein1e-44180
NC_012121:1676367:168309416830941683900807Staphylococcus carnosus subsp. carnosus TM300, complete genomehypothetical protein1e-44179
NC_013525:1953920:195796219579621958762801Thermobaculum terrenum ATCC BAA-798 chromosome 1, complete genomeprotein of unknown function DUF1471e-43176
NC_011134:1222739:124484512448451245696852Streptococcus equi subsp. zooepidemicus str. MGCS10565, completehypothetical protein3e-43175
NC_011900:1485650:148565014856501486507858Streptococcus pneumoniae ATCC 700669, complete genomehypothetical protein6e-42171
NC_011244:1:213152131522091777Borrelia recurrentis A1, complete genomehypothetical protein1e-38160
NC_013939:1023443:103121610312161031983768Deferribacter desulfuricans SSM1, complete genomehypothetical protein8e-38157
NC_010673:908940:873987399515777Borrelia hermsii DAH, complete genomehypothetical membrane spanning protein3e-37155
NC_014758:1489761:150580615058061506585780Calditerrivibrio nitroreducens DSM 19672 chromosome, completehypothetical protein5e-37154
NC_012438:1514376:151773615177361518575840Sulfurihydrogenibium azorense Az-Fu1 chromosome, complete genomehypothetical protein1e-36153
NC_008710:900586:844084409216777Borrelia turicatae 91E135, complete genomehypothetical membrane spanning protein2e-36152
NC_015388:1678000:168066216806621681465804Desulfobacca acetoxidans DSM 11109 chromosome, complete genomeConserved hypothetical protein CHP001591e-35150
NC_011565:69427:884918849189255765Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2,hypothetical protein1e-35150
NC_008011:213386:239839239839240579741Lawsonia intracellularis PHE/MN1-00, complete genomehypothetical protein9e-34144
NC_006274:4742489:475032547503254750930606Bacillus cereus E33L, complete genomehypothetical protein9e-31134
NC_005957:4680089:468597846859784686583606Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein8e-31134
NC_007530:4674335:468015546801554680760606Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein2e-30133
NC_005945:4670978:468125246812524681857606Bacillus anthracis str. Sterne, complete genomehypothetical protein2e-30133
NC_003997:4674209:468002946800294680634606Bacillus anthracis str. Ames, complete genomehypothetical protein2e-30133
NC_011773:4732457:474029447402944740899606Bacillus cereus AH820 chromosome, complete genomehypothetical protein2e-30133
NC_012659:4674235:468005546800554680660606Bacillus anthracis str. A0248, complete genomehypothetical protein2e-30133
NC_017200:4697500:470485847048584705463606Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein2e-30133
NC_012472:4691251:469908846990884699693606Bacillus cereus 03BB102, complete genomehypothetical protein1e-30133
NC_016779:4645155:465299246529924653597606Bacillus cereus F837/76 chromosome, complete genomehypothetical protein1e-30133
NC_008600:4687500:469536046953604695974615Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein1e-30133
NC_004722:4824818:483100948310094831614606Bacillus cereus ATCC 14579, complete genomehypothetical Membrane Spanning Protein4e-30132
NC_014171:4740500:474695547469554747560606Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein4e-30132
NC_011658:4672000:468090146809014681506606Bacillus cereus AH187 chromosome, complete genomehypothetical protein3e-30132
NC_011969:4613430:462126546212654621870606Bacillus cereus Q1 chromosome, complete genomehypothetical protein3e-30132
NC_014335:4622500:463034446303444630949606Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein7e-30130
NC_015703:3325780:332719833271983327995798Runella slithyformis DSM 19594 chromosome, complete genomehypothetical protein2e-29129
NC_013730:3208571:323619732361973237015819Spirosoma linguale DSM 74, complete genomeprotein of unknown function DUF1475e-29128
NC_008312:3728329:374819637481963749110915Trichodesmium erythraeum IMS101, complete genomeprotein of unknown function DUF1473e-27122
NC_010382:3350816:335136133513613351951591Lysinibacillus sphaericus C3-41, complete genomehypothetical protein2e-23109