Pre_GI: BLASTP Hits

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Query: NC_012563:3921859:3938227 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 3938227, End: 3939507, Length: 1281

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010516:3724312:3741376374137637426561281Clostridium botulinum B1 str. Okra, complete genomehypothetical protein0692
NC_009698:3526359:3543421354342135447011281Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein0692
NC_009697:3629250:3646312364631236475921281Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein0692
NC_017297:3752000:3771769377176937730491281Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein0691
NC_009699:3753599:3773155377315537744351281Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein0691
NC_012658:3744000:3761239376123937625191281Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein0688
NC_010520:3753875:3770890377089037721701281Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein0680
NC_014328:4387303:4400678440067844019341257Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein9e-75281
NC_008261:2920999:2931833293183329331581326Clostridium perfringens ATCC 13124, complete genomehypothetical protein3e-37156
NC_015555:386000:3917193917193929091191Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeYbbR family protein1e-31137
NC_009922:2590317:2592158259215825933781221Alkaliphilus oremlandii OhILAs, complete genomeYbbR family protein2e-26120
NC_003869:2099000:2115893211589321170951203Thermoanaerobacter tengcongensis MB4, complete genomehypothetical protein2e-23110
NC_015565:287900:290700290700291680981Desulfotomaculum carboxydivorans CO-1-SRB chromosome, completeYbbR family protein5e-23109
NC_015958:2206032:2236447223644722376371191Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomeYbbR family protein6e-21102
NC_014538:1942500:1955883195588319570731191Thermoanaerobacter sp. X513 chromosome, complete genomeYbbR family protein5e-2099.4
NC_010718:237962:2497572497572510041248Natranaerobius thermophilus JW/NM-WN-LF, complete genomeYbbR family protein2e-1790.5
NC_009089:117980:1547691547691559501182Clostridium difficile 630, complete genomehypothetical protein4e-1582.8
NC_015589:366296:367117367117368085969Desulfotomaculum ruminis DSM 2154 chromosome, complete genomeYbbR family protein7e-1582.4
NC_021184:592501:596835596835597788954Desulfotomaculum gibsoniae DSM 7213, complete genomehypothetical protein2e-1377.8
NC_012034:390273:4150934150934163251233Anaerocellum thermophilum DSM 6725, complete genomeYbbR family protein2e-1377.4
NC_013171:416279:419380419380420315936Anaerococcus prevotii DSM 20548, complete genomeYbbR family protein1e-1067.8
NC_013316:120759:1503481503481514601113Clostridium difficile R20291, complete genomehypothetical protein2e-1067
NC_014551:199500:2018432018432032731431Bacillus amyloliquefaciens DSM 7, complete genomehypothetical protein1e-0861.6
NC_017190:182449:1846321846321860621431Bacillus amyloliquefaciens LL3 chromosome, complete genomehypothetical protein1e-0861.6
NC_017191:183500:1857321857321871621431Bacillus amyloliquefaciens XH7 chromosome, complete genomehypothetical protein2e-0860.8
NC_017188:177500:1798221798221812521431Bacillus amyloliquefaciens TA208 chromosome, complete genomehypothetical protein2e-0860.8
NC_009725:200071:2008852008852023241440Bacillus amyloliquefaciens FZB42, complete genomeYbbR3e-0860.1
NC_020410:198000:2009272009272023661440Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completeYbbR-like domain-containing protein ybbR3e-0860.1
NC_011567:139598:1539921539921552241233Anoxybacillus flavithermus WK1, complete genomehypothetical protein3e-0860.1
NC_020272:3706722:3724864372486437263031440Bacillus amyloliquefaciens IT-45, complete genomeReplicase polyprotein 1ab pp1ab3e-0860.1
NC_014614:554949:5763795763795775811203Clostridium sticklandii, complete genomeexported protein of unknown function9e-0858.5
UCMB5137:3857960:3859577385957738610161440Bacillus atrophaeus UCMB-5137hypothetical protein1e-0758.2
NC_019897:329945:3486753486753499281254Thermobacillus composti KWC4 chromosome, complete genomehypothetical protein2e-0653.9
NC_011830:923424:9258949258949272071314Desulfitobacterium hafniense DCB-2, complete genomeYbbR family protein8e-0652