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Query: NC_012563:3556763:3560408 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 3560408, End: 3560878, Length: 471

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:3185359:319137331913733191843471Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein3e-85313
NC_009697:3291500:329426632942663294736471Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein3e-85313
NC_009495:3309550:331827733182773318747471Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein3e-85313
NC_010516:3368951:337890733789073379377471Clostridium botulinum B1 str. Okra, complete genomehypothetical protein7e-84308
NC_012658:3387774:339667133966713397141471Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein1e-83308
NC_003366:2143173:215465021546502155093444Clostridium perfringens str. 13, complete genomehypothetical protein2e-50197
NC_014328:3747973:375556837555683756032465Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein1e-49194
NC_008262:2025699:203859420385942039037444Clostridium perfringens SM101, complete genomehypothetical protein1e-49194
NC_020291:1149887:116360011636001164328729Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehypothetical protein2e-43174
NC_014209:1487699:150666915066691507100432Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,protein of unknown function DUF5231e-40165
NC_020272:3706722:372930637293063729758453Bacillus amyloliquefaciens IT-45, complete genomehypothetical protein1e-36152
NC_014377:1335963:135492113549211355379459Thermosediminibacter oceani DSM 16646 chromosome, complete genomeprotein of unknown function DUF5231e-34145
NC_015320:211147:229538229538230035498Archaeoglobus veneficus SNP6 chromosome, complete genomehypothetical protein2e-34144
NC_017208:4887334:490716149071614907622462Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeputative cytoplasmic protein7e-33139
NC_011658:4672000:469065646906564691117462Bacillus cereus AH187 chromosome, complete genomehypothetical protein2e-32138
NC_011969:4613430:463104146310414631502462Bacillus cereus Q1 chromosome, complete genomehypothetical protein3e-32137
NC_007644:626992:642042642042642515474Moorella thermoacetica ATCC 39073, complete genomeProtein of unknown function DUF5233e-32137
NC_009253:1381401:140006914000691400566498Desulfotomaculum reducens MI-1 chromosome, complete genomehypothetical protein4e-31133
NC_014150:2924158:293125329312532931690438Brachyspira murdochii DSM 12563 chromosome, complete genomeprotein of unknown function DUF5236e-31132
NC_007333:1411050:141258214125821413082501Thermobifida fusca YX, complete genomehypothetical protein6e-27119
NC_014387:3227875:324590932459093246328420Butyrivibrio proteoclasticus B316 chromosome 1, complete genomehypothetical protein8e-27119
NC_014532:1307983:131551313155131315989477Halomonas elongata DSM 2581, complete genomeprotein of unknown function DUF5232e-26118
NC_016745:2280375:228517922851792285667489Oceanimonas sp. GK1 chromosome, complete genomehypothetical protein1e-25115
NC_013204:2305140:2321102232110223221661065Eggerthella lenta DSM 2243, complete genomeprotein of unknown function DUF5232e-24111
NC_006138:2630338:265103326510332651524492Desulfotalea psychrophila LSv54, complete genomehypothetical protein2e-24111
NC_013421:3093995:310180631018063102312507Pectobacterium wasabiae WPP163, complete genomeprotein of unknown function DUF5231e-23108
NC_013510:1786194:179995117999511800472522Thermomonospora curvata DSM 43183, complete genomeprotein of unknown function DUF5239e-23105
NC_013850:3303500:330696233069623307471510Klebsiella variicola At-22 chromosome, complete genomeprotein of unknown function DUF5234e-22103
NC_009706:238160:242175242175242597423Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein2e-1891.3
NC_015500:1204501:121525212152521215674423Treponema brennaborense DSM 12168 chromosome, complete genomeprotein of unknown function DUF5232e-1891.3
NC_011837:238160:242175242175242606432Clostridium kluyveri NBRC 12016, complete genomehypothetical protein2e-1891.3