Pre_GI: BLASTP Hits

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Query: NC_012563:2979147:2990817 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2990817, End: 2991818, Length: 1002

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009697:2680607:2689665268966526906661002Clostridium botulinum A str. ATCC 19397 chromosome, completeV-type ATP synthase subunit C1e-180632
NC_008593:841291:8509748509748519751002Clostridium novyi NT, complete genomeATP synthase (C/AC39) subunit1e-94346
NC_015425:906969:9165789165789175791002Clostridium botulinum BKT015925 chromosome, complete genomeATP synthase (C/AC39) subunit1e-85317
NC_010674:2930259:2939551293955129405521002Clostridium botulinum B str. Eklund 17B, complete genomeATP synthase (C/AC39) subunit3e-85315
NC_010723:2735196:2743864274386427448651002Clostridium botulinum E3 str. Alaska E43, complete genomeATP synthase (C/AC39) subunit2e-84312
NC_008261:2117207:2127848212784821288551008Clostridium perfringens ATCC 13124, complete genomeV-type ATPase, C subunit5e-74278
NC_008262:1795914:1801899180189918029061008Clostridium perfringens SM101, complete genomeV-type ATPase, C subunit4e-74278
NC_003366:1901898:1912538191253819135451008Clostridium perfringens str. 13, complete genomeATP synthase subunit C7e-74277
NC_013192:815854:825787825787826785999Leptotrichia buccalis DSM 1135, complete genomeH(+)-transporting two-sector ATPase3e-63242
NC_014377:2033781:2056069205606920570731005Thermosediminibacter oceani DSM 16646 chromosome, complete genomeH+transporting two-sector ATPase C (AC39) subunit2e-52206
NC_014964:2301835:2312457231245723134611005Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completeH+transporting two-sector ATPase C (AC39) subunit4e-52205
NC_010321:2319820:2330442233044223314461005Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completeV-type ATP synthase subunit C4e-52205
NC_010320:2397395:2409694240969424106981005Thermoanaerobacter sp. X514 chromosome, complete genomeV-type ATP synthase subunit C6e-52204
NC_014538:2396559:2408858240885824098621005Thermoanaerobacter sp. X513 chromosome, complete genomeH+transporting two-sector ATPase C (AC39) subunit6e-52204
NC_013921:2375900:2387882238788223888861005Thermoanaerobacter italicus Ab9 chromosome, complete genomeH+transporting two-sector ATPase C (AC39) subunit2e-51202
NC_014209:2257316:2269300226930022703041005Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,H+transporting two-sector ATPase C (AC39) subunit8e-51201
NC_017179:3222015:323163332316333232610978Clostridium difficile BI1, complete genomeV-type ATP synthase subunit C1e-48193
NC_013315:3214063:322368132236813224658978Clostridium difficile CD196 chromosome, complete genomeV-type ATP synthase subunit C1e-48193
NC_015562:627000:6351986351986363641167Methanotorris igneus Kol 5 chromosome, complete genomeV-type ATP synthase subunit C2e-28127
NC_013407:1610221:1617223161722316184221200Methanocaldococcus vulcanius M7, complete genomeATP synthase A1, C subunit2e-27123
NC_000909:201000:2093152093152105141200Methanocaldococcus jannaschii DSM 2661, complete genomeV-type ATP synthase subunit C2e-26119
NC_014122:393856:4043954043954055401146Methanocaldococcus infernus ME chromosome, complete genomeATP synthase A1, C subunit2e-25116
NC_016148:1021138:1021138102113810221511014Thermovirga lienii DSM 17291 chromosome, complete genomeH+transporting two-sector ATPase C (AC39) subunit6e-25115
NC_013156:431795:4406204406204418191200Methanocaldococcus fervens AG86, complete genomeATP synthase A1, C subunit2e-24113
NC_009635:61344:6959969599707501152Methanococcus aeolicus Nankai-3 chromosome, complete genomeV-type ATP synthase subunit C8e-23108
NC_009637:302881:3124033124033135781176Methanococcus maripaludis C7 chromosome, complete genomeV-type ATP synthase subunit C2e-22107
NC_005791:1028500:1035217103521710363921176Methanococcus maripaludis S2, complete genomeV-type ATP synthase subunit C1e-21104
NC_015847:1119666:1129331112933111305061176Methanococcus maripaludis XI chromosome, complete genomeV-type ATP synthase subunit C8e-22104
NC_009975:1500978:1510213151021315113881176Methanococcus maripaludis C6, complete genomeATP synthase A1, C subunit2e-21103
NC_009135:494949:5047695047695059441176Methanococcus maripaludis C5, complete genomeH+-transporting two-sector ATPase, C (AC39) subunit2e-21103
NC_009785:130252:1371111371111381241014Streptococcus gordonii str. Challis substr. CH1, complete genomeATP synthase (C/AC39) subunit3e-21102
NC_009634:411599:4214914214914226631173Methanococcus vannielii SB chromosome, complete genomeV-type ATP synthase subunit C7e-2098.2
NC_015636:1477221:1487791148779114888761086Methanothermococcus okinawensis IH1 chromosome, complete genomeV-type ATP synthase subunit C2e-1996.7
NC_014222:186876:1951521951521963181167Methanococcus voltae A3 chromosome, complete genomeATP synthase A1, C subunit3e-1789.7
NC_015216:405657:4132334132334143901158Methanobacterium sp. AL-21 chromosome, complete genomeV-type ATP synthase subunit C2e-1480.1
NC_015574:2057602:2067410206741020685671158Methanobacterium sp. SWAN-1 chromosome, complete genomeV-type ATP synthase subunit C1e-1274.3
NC_013741:1390823:1398243139824313992651023Archaeoglobus profundus DSM 5631, complete genomeATP synthase A1, C subunit6e-1065.1
NC_000868:1730820:1742727174272717438391113Pyrococcus abyssi GE5, complete genomeV-type ATP synthase subunit C1e-0963.9
NC_007681:1300068:1309350130935013105071158Methanosphaera stadtmanae DSM 3091, complete genomeAhaC3e-0859.7
NC_005877:509877:5218385218385228841047Picrophilus torridus DSM 9790, complete genomeV-type ATP synthase subunit C5e-0858.9
NC_012883:1603744:1615303161530316164121110Thermococcus sibiricus MM 739, complete genomeA1A0 ATP synthase, subunit C1e-0757.8