Pre_GI: BLASTP Hits

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Query: NC_012563:2761570:2764891 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2764891, End: 2765073, Length: 183

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009495:2571732:259036925903692590560192Clostridium botulinum A str. ATCC 3502 chromosome, complete genome50S ribosomal protein L324e-29126
NC_010516:2567911:257859425785942578776183Clostridium botulinum B1 str. Okra, complete genomeribosomal protein L324e-29126
NC_010520:2635750:265339626533962653578183Clostridium botulinum A3 str. Loch Maree, complete genomeribosomal protein L32 family protein4e-29126
NC_009698:2420484:243473624347362434918183Clostridium botulinum A str. Hall chromosome, complete genome50S ribosomal protein L324e-29126
NC_009699:2635745:263906626390662639248183Clostridium botulinum F str. Langeland chromosome, complete genome50S ribosomal protein L324e-29126
NC_012658:2641446:264861126486112648793183Clostridium botulinum Ba4 str. 657 chromosome, complete genome50S ribosomal protein L324e-29126
NC_017297:2635892:263921326392132639395183Clostridium botulinum F str. 230613 chromosome, complete genome50S ribosomal protein L324e-29126
NC_015958:1422319:143556414355641435746183Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genome50S ribosomal protein L325e-1373.2
NC_005945:3725397:374530637453063745584279Bacillus anthracis str. Sterne, complete genome50S ribosomal protein L326e-1372.8
NC_006274:3805134:382504838250483825326279Bacillus cereus E33L, complete genome50S ribosomal protein L326e-1372.8
NC_005957:3746891:376677737667773767055279Bacillus thuringiensis serovar konkukian str. 97-27, complete50S ribosomal protein L326e-1372.8
NC_002976:707827:713016713016713189174Staphylococcus epidermidis RP62A, complete genome50S ribosomal protein L329e-1372.4
NC_004461:813748:818938818938819111174Staphylococcus epidermidis ATCC 12228, complete genome50S ribosomal protein L329e-1372.4
NC_014964:1309845:132374613237461323928183Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, complete50S ribosomal protein L329e-1372
NC_003997:3724702:374480637448063744979174Bacillus anthracis str. Ames, complete genome50S ribosomal protein L321e-1271.6
NC_007530:3724829:374493337449333745106174Bacillus anthracis str. 'Ames Ancestor', complete genome50S ribosomal protein L321e-1271.6
NC_014335:3675456:369537436953743695547174Bacillus cereus biovar anthracis str. CI chromosome, complete50S ribosomal protein L321e-1271.6
NC_012659:3724729:374483337448333745006174Bacillus anthracis str. A0248, complete genome50S ribosomal protein L321e-1271.6
NC_014171:3812247:382962438296243829797174Bacillus thuringiensis BMB171 chromosome, complete genome50S ribosomal protein L32P1e-1271.6
NC_016771:3665773:368560536856053685778174Bacillus cereus NC7401, complete genome50S ribosomal protein L321e-1271.6
NC_007498:1666242:168142916814291681605177Pelobacter carbinolicus DSM 2380, complete genomeribosomal protein L322e-1271.2
NC_013316:1225797:123306512330651233241177Clostridium difficile R20291, complete genome50S ribosomal protein L325e-1269.7
NC_013315:1230214:123544912354491235625177Clostridium difficile CD196 chromosome, complete genome50S ribosomal protein L325e-1269.7
NC_017179:1239991:124522612452261245402177Clostridium difficile BI1, complete genome50S ribosomal protein L325e-1269.7
NC_014483:1954856:196560619656061965779174Paenibacillus polymyxa E681 chromosome, complete genome50S ribosomal protein L322e-1168.2
NC_014831:1140356:115379211537921153971180Thermaerobacter marianensis DSM 12885 chromosome, complete genomeLSU ribosomal protein L32P2e-1167.8
NC_014622:2114244:212501221250122125185174Paenibacillus polymyxa SC2 chromosome, complete genome50S ribosomal protein L323e-1167.4
NC_016048:1930089:196110019611001961303204Oscillibacter valericigenes Sjm18-20, complete genome50S ribosomal protein L323e-1167.4
NC_014624:2668157:268228326822832682459177Eubacterium limosum KIST612 chromosome, complete genomeprotein RpmF4e-0960.1
NC_004668:1010610:101336710133671013546180Enterococcus faecalis V583, complete genome50S ribosomal protein L327e-0959.3
NC_007517:1792000:179882717988271799009183Geobacter metallireducens GS-15, complete genomeribosomal protein S322e-0857.8
NC_011661:961129:969589969589969780192Dictyoglomus turgidum DSM 6724, complete genomeribosomal protein L322e-0857.8
NC_011297:787932:798740798740798931192Dictyoglomus thermophilum H-6-12, complete genomeribosomal protein L325e-0856.2
NS_000191:870160:885658885658885876219Uncultured Termite group 1 bacterium phylotype Rs-D17, complete50S ribosomal protein L321e-0755.1
NC_020419:870160:885658885658885876219Uncultured Termite group 1 bacterium phylotype Rs-D17 DNA, complete50S ribosomal protein L321e-0755.1
NC_015185:875324:891504891504891683180Desulfurobacterium thermolithotrophum DSM 11699 chromosome,50S ribosomal protein L321e-0755.1
NC_015738:1858455:187699018769901877169180Eggerthella sp. YY7918, complete genome50S ribosomal protein L323e-0753.9
NC_015499:1466794:148386514838651484062198Thermodesulfobium narugense DSM 14796 chromosome, complete genome50S ribosomal protein L321e-0652
NC_004722:3886800:39067573906757390685296Bacillus cereus ATCC 14579, complete genomeLSU ribosomal protein L32P2e-0650.8
NC_019978:1410041:142502714250271425194168Halobacteroides halobius DSM 5150, complete genomeribosomal protein L323e-0650.8
NC_011027:136954:151834151834152025192Chlorobaculum parvum NCIB 8327, complete genomeribosomal protein L324e-0650.1
NC_010831:173499:179811179811180002192Chlorobium phaeobacteroides BS1, complete genomeribosomal protein L325e-0649.7
NC_010644:718748:723129723129723335207Elusimicrobium minutum Pei191, complete genomeribosomal protein L325e-0649.7