Pre_GI: BLASTP Hits

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Query: NC_012563:2721658:2739744 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2739744, End: 2740460, Length: 717

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010163:1193237:121106412110641211783720Acholeplasma laidlawii PG-8A chromosome, complete genomeuridylate kinase7e-72270
NC_011145:306623:329618329618330373756Anaeromyxobacter sp. K, complete genomeuridylate kinase3e-76284
NC_007797:107950:107950107950108243294Anaplasma phagocytophilum HZ, complete genomeuridylate kinase, truncation9e-1063.9
NC_007797:107950:117715117715118449735Anaplasma phagocytophilum HZ, complete genomeuridylate kinase2e-57221
NC_000918:465627:488204488204488926723Aquifex aeolicus VF5, complete genomeUMP kinase4e-74277
NC_007530:3616828:364042336404233641145723Bacillus anthracis str. 'Ames Ancestor', complete genomeuridylate kinase4e-77287
NC_012659:3617000:364032336403233641045723Bacillus anthracis str. A0248, complete genomeuridylate kinase4e-77287
NC_003997:3617000:364029636402963641018723Bacillus anthracis str. Ames, complete genomeuridylate kinase4e-77287
NC_012581:559182:597542597542598264723Bacillus anthracis str. CDC 684 chromosome, complete genomeuridylate kinase4e-77287
NC_005945:3636321:364099136409913641713723Bacillus anthracis str. Sterne, complete genomeuridylate kinase4e-77287
NC_011658:3603009:362834036283403629062723Bacillus cereus AH187 chromosome, complete genomeuridylate kinase4e-77287
NC_003909:3606177:361569436156943616416723Bacillus cereus ATCC 10987, complete genomeuridylate kinase4e-77287
NC_011725:3821789:384501438450143845736723Bacillus cereus B4264 chromosome, complete genomeuridylate kinase3e-77287
NC_014335:3589726:359114835911483591870723Bacillus cereus biovar anthracis str. CI chromosome, completeuridylate kinase4e-77287
NC_006274:3697255:372084937208493721571723Bacillus cereus E33L, complete genomeuridylate kinase4e-77287
NC_011772:3787500:381073338107333811455723Bacillus cereus G9842, complete genomeuridylate kinase5e-77287
NC_014171:3701051:372427437242743724996723Bacillus thuringiensis BMB171 chromosome, complete genomeuridylate kinase3e-77287
NC_017208:3816753:384040938404093841131723Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeuridylate kinase5e-77287
NC_009614:2431005:244757324475732448283711Bacteroides vulgatus ATCC 8482 chromosome, complete genomeuridylate kinase5e-49194
NC_020300:675551:682111682111682830720Bartonella australis Aust/NH1, complete genomeuridylate kinase3e-53208
NC_018604:2053585:208948820894882090192705Brachyspira pilosicoli WesB complete genomeaspartate/glutamate/uridylate kinase3e-47188
NC_004545:229771:251299251299252027729Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genomeuridylate kinase2e-38159
NC_004061:237205:258047258047258769723Buchnera aphidicola str. Sg (Schizaphis graminum), complete genomeuridylate kinase2e-47188
NC_017096:779550:790769790769791482714Caldisericum exile AZM16c01, complete genomeuridylate kinase5e-46184
NC_019791:1189908:120002312000231200703681Caldisphaera lagunensis DSM 15908 chromosome, complete genomeuridylate kinase4e-1168.6
NC_017294:758992:767319767319768026708Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomeuridylate kinase8e-87320
NC_012985:465354:485335485335486063729Candidatus Liberibacter asiaticus str. psy62, complete genomeuridylate kinase1e-46186
NC_013895:1086500:108657110865711087278708Clostridiales genomosp. BVAB3 str. UPII9-5 chromosome, completeUMP kinase8e-65246
NC_016627:2799453:282884428288442829551708Clostridium clariflavum DSM 19732 chromosome, complete genomeuridylate kinase1e-83308
NC_016787:1509831:150983115098311510562732Corynebacterium diphtheriae HC03 chromosome, complete genomeuridylate kinase1e-61236
NC_016788:1509943:151329615132961514027732Corynebacterium diphtheriae HC04 chromosome, complete genomeuridylate kinase1e-61236
NC_016790:1480441:148579214857921486523732Corynebacterium diphtheriae VA01 chromosome, complete genomeuridylate kinase4e-62238
NC_017300:1426975:142872814287281429459732Corynebacterium pseudotuberculosis 1002 chromosome, completeuridylate kinase3e-61234
NC_016781:1408235:143130914313091432040732Corynebacterium pseudotuberculosis 3/99-5 chromosome, completeuridylate kinase3e-61234
NC_016932:1414226:141595914159591416708750Corynebacterium pseudotuberculosis 316 chromosome, complete genomeuridylate kinase1e-53209
NC_017301:1425293:143111614311161431847732Corynebacterium pseudotuberculosis C231 chromosome, completeuridylate kinase3e-61234
NC_014329:1407880:143137114313711432102732Corynebacterium pseudotuberculosis FRC41 chromosome, completeuridylate kinase3e-61234
NC_017303:1420758:143119414311941431925732Corynebacterium pseudotuberculosis I19 chromosome, complete genomeuridylate kinase3e-61234
NC_017031:1420738:143117314311731431904732Corynebacterium pseudotuberculosis P54B96 chromosome, completeuridylate kinase3e-61234
NC_013216:3408608:341046734104673411195729Desulfotomaculum acetoxidans DSM 771, complete genomeuridylate kinase8e-83306
NC_015185:1414453:141445314144531415175723Desulfurobacterium thermolithotrophum DSM 11699 chromosome,uridylate kinase6e-77286
NC_012778:841934:860392860392861096705Eubacterium eligens ATCC 27750, complete genomeuridylate kinase7e-54210
NC_014624:2297000:229763822976382298351714Eubacterium limosum KIST612 chromosome, complete genomeuridylate kinase3e-86317
NC_015696:220798:229836229836230585750Francisella sp. TX077308 chromosome, complete genomeUridylate kinase4e-49194
NC_009749:221311:226451226451227200750Francisella tularensis subsp. holarctica FTA, complete genomeuridylate kinase6e-50197
NC_008369:221382:226522226522227271750Francisella tularensis subsp. holarctica OSU18, complete genomeuridylate kinase6e-50197
NC_007880:221674:226814226814227563750Francisella tularensis subsp. holarctica, complete genomeuridylate kinase6e-50197
NC_010677:1621500:164533516453351646084750Francisella tularensis subsp. mediasiatica FSC147, complete genomeuridylate kinase9e-50196
NC_008601:246583:251805251805252554750Francisella tularensis subsp. novicida U112, complete genomeuridylate kinase9e-50196
NC_008245:324926:330063330063330812750Francisella tularensis subsp. tularensis FSC 198, complete genomeuridylate kinase9e-50196
NC_006570:324974:330111330111330860750Francisella tularensis subsp. tularensis Schu 4, complete genomeuridylate kinase9e-50196
NC_016937:324883:330020330020330769750Francisella tularensis subsp. tularensis TI0902 chromosome,uridylate kinase9e-50196
NC_009257:1636633:166101716610171661766750Francisella tularensis subsp. tularensis WY96-3418 chromosome,uridylate kinase9e-50196
NC_016933:400790:405927405927406676750Francisella tularensis TIGB03 chromosome, complete genomeuridylate kinase9e-50196
NC_016933:324883:330020330020330769750Francisella tularensis TIGB03 chromosome, complete genomeuridylate kinase9e-50196
NC_007777:5087405:509176350917635092542780Frankia sp. CcI3, complete genomeUridylate kinase7e-44177
NC_003454:128000:129780129780130499720Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completeUridylate kinase9e-76283
NC_008358:1789816:181399118139911814746756Hyphomonas neptunium ATCC 15444, complete genomeuridylate kinase2e-57222
NC_014471:1269571:127440812744081275088681Ignisphaera aggregans DSM 17230 chromosome, complete genomeuridylate kinase2e-1169.3
NC_013192:1765981:177170717717071772423717Leptotrichia buccalis DSM 1135, complete genomeuridylate kinase2e-66252
NC_019907:46994:554565545656175720Liberibacter crescens BT-1 chromosome, complete genomeuridylate kinase4e-39161
NC_014759:3572500:357313135731313573844714Marivirga tractuosa DSM 4126 chromosome, complete genomeuridylate kinase5e-64244
NC_013156:21781:328023280233482681Methanocaldococcus fervens AG86, complete genomeuridylate kinase2e-1272.4
NC_014122:967194:977795977795978472678Methanocaldococcus infernus ME chromosome, complete genomeuridylate kinase3e-0652
NC_010794:1673049:169365516936551694416762Methylacidiphilum infernorum V4, complete genomeUridylate kinase2e-66251
NC_014815:1686409:170903117090311709798768Micromonospora sp. L5 chromosome, complete genomeuridylate kinase3e-50198
NC_020133:2144752:215184921518492152646798Mycobacterium liflandii 128FXT, complete genomeuridylate kinase PyrH3e-61234
NC_010612:2215724:222145022214502222247798Mycobacterium marinum M, complete genomeuridylate kinase PyrH8e-62236
NC_011025:46903:501615016150883723Mycoplasma arthritidis 158L3-1, complete genomeuridylate kinase9e-46183
NC_007633:446899:461283461283461996714Mycoplasma capricolum subsp. capricolum ATCC 27343, completeuridylate kinase1e-32139
NC_014751:449001:463379463379464092714Mycoplasma leachii PG50 chromosome, complete genomeUMP kinase2e-32139
NC_002946:1935186:195048619504861951205720Neisseria gonorrhoeae FA 1090, complete genomeuridylate kinase2e-53209
NC_011035:1876555:188204918820491882768720Neisseria gonorrhoeae NCCP11945 chromosome, complete genomeuridylate kinase2e-53209
NC_017511:1783000:178864217886421789361720Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomeuridylate kinase3e-53208
NC_014752:197000:218299218299219018720Neisseria lactamica ST-640, complete genomeuridylate kinase5e-53207
NC_010120:2098000:210365121036512104370720Neisseria meningitidis 053442, complete genomeuridylate kinase3e-53208
NC_017501:2219803:222556222255622226281720Neisseria meningitidis 8013, complete genomeuridylate kinase (UK; uridine monophosphate kinase; UMP kinase)3e-53208
NC_013016:44188:599645996460683720Neisseria meningitidis alpha14 chromosome, complete genomeuridylate kinase6e-53207
NC_017505:2192284:219778121977812198662882Neisseria meningitidis alpha710 chromosome, complete genomeuridylate kinase7e-53207
NC_008767:2126854:213250521325052133224720Neisseria meningitidis FAM18, complete genomeuridylate kinase3e-53208
NC_017513:2134308:213995621399562140675720Neisseria meningitidis G2136 chromosome, complete genomeUMP kinase3e-53208
NC_017516:2183708:218935521893552190074720Neisseria meningitidis H44/76 chromosome, complete genomeUMP kinase6e-53207
NC_017514:2165166:217081921708192171538720Neisseria meningitidis M01-240149 chromosome, complete genomeUMP kinase3e-53208
NC_017517:2228000:223173722317372232456720Neisseria meningitidis M01-240355 chromosome, complete genomeUMP kinase3e-52204
NC_017515:2194500:219853821985382199257720Neisseria meningitidis M04-240196 chromosome, complete genomeUMP kinase6e-53207
NC_003112:2215184:222083122208312221550720Neisseria meningitidis MC58, complete genomeuridylate kinase6e-53207
NC_017518:2190607:219626021962602196979720Neisseria meningitidis NZ-05/33 chromosome, complete genomeUMP kinase3e-53208
NC_017512:52228:676806768068399720Neisseria meningitidis WUE 2594, complete genomeuridylate kinase6e-53207
NC_003116:291661:307114307114307833720Neisseria meningitidis Z2491, complete genomeuridylate kinase6e-53207
NC_007484:882341:883230883230883961732Nitrosococcus oceani ATCC 19707, complete genomeuridylate kinase4e-63241
NC_014315:2485527:250343525034352504166732Nitrosococcus watsoni C-113 chromosome, complete genomeuridylate kinase3e-63241
NC_015731:3658956:368148136814813682197717Nitrosomonas sp. Is79A3 chromosome, complete genomeuridylate kinase2e-59228
NC_012440:197728:205513205513206223711Persephonella marina EX-H1, complete genomeUMP kinase7e-72270
NC_015571:168617:193995193995194714720Porphyromonas gingivalis TDC60, complete genomeuridylate kinase1e-48193
NC_002950:1981155:200151820015182002237720Porphyromonas gingivalis W83, complete genomeuridylate kinase1e-49196
NC_000868:696296:700949700949701626678Pyrococcus abyssi GE5, complete genomeuridylate kinase1e-0757
NC_015474:1849509:185963218596321860309678Pyrococcus sp. NA2 chromosome, complete genomeuridylate kinase8e-0960.8
NC_009953:1364500:138105113810511381806756Salinispora arenicola CNS-205 chromosome, complete genomeuridylate kinase9e-51200
NC_017068:638868:668089668089668814726Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative uridylate kinase2e-82305
NC_015437:572788:585686585686586414729Selenomonas sputigena ATCC 35185 chromosome, complete genomeuridylate kinase8e-82303
NC_016632:398018:406736406736407461726Serratia symbiotica str. 'Cinara cedri' chromosome, completeuridylate kinase1e-51202
NC_014012:1421979:144259714425971443337741Shewanella violacea DSS12, complete genomeuridylate kinase6e-52204
NC_004461:921364:935848935848936570723Staphylococcus epidermidis ATCC 12228, complete genomeuridylate kinase1e-78292
NC_007168:1705763:170961417096141710336723Staphylococcus haemolyticus JCSC1435, complete genomeuridylate kinase1e-78292
NC_007350:1551457:156891715689171569639723Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305,uridylate kinase1e-77289
NC_015678:966000:970809970809971540732Streptococcus parasanguinis ATCC 15912 chromosome, complete genomeUMP kinase2e-74278
NC_003888:6103534:612556361255636126324762Streptomyces coelicolor A3(2), complete genomeuridylate kinase9e-59226
NC_021177:6127431:614967061496706150446777Streptomyces fulvissimus DSM 40593, complete genomeUridylate kinase3e-59228
NC_007181:1094422:111282911128291113512684Sulfolobus acidocaldarius DSM 639, complete genomeuridylate kinase3e-0652.4
NC_017275:1189162:120311512031151203795681Sulfolobus islandicus HVE10/4 chromosome, complete genomeuridylate kinase6e-0754.3
NC_012589:1241782:125574812557481256428681Sulfolobus islandicus L.S.2.15, complete genomeuridylate kinase6e-0754.3
NC_012632:1249334:126636812663681267048681Sulfolobus islandicus M.16.27 chromosome, complete genomeuridylate kinase6e-0651.2
NC_017276:1051707:106751110675111068191681Sulfolobus islandicus REY15A chromosome, complete genomeuridylate kinase6e-0754.3
NC_012623:1405893:140905014090501409730681Sulfolobus islandicus Y.N.15.51 chromosome, complete genomeuridylate kinase6e-0754.3
NC_002754:824180:834557834557835240684Sulfolobus solfataricus P2, complete genomeuridylate kinase1e-0653.5
NC_012438:159927:172242172242172952711Sulfurihydrogenibium azorense Az-Fu1 chromosome, complete genomeuridylate kinase2e-72271
NC_010730:578493:590355590355591065711Sulfurihydrogenibium sp. YO3AOP1, complete genomeuridylate kinase6e-71266
NC_008346:983816:100155710015571002273717Syntrophomonas wolfei subsp. wolfei str. Goettingen, completehypothetical protein2e-77288
NC_013894:1380564:138707313870731387780708Thermocrinis albus DSM 14484 chromosome, complete genomeuridylate kinase1e-70266
NC_015499:1372361:139246013924601393164705Thermodesulfobium narugense DSM 14796 chromosome, complete genomeuridylate kinase8e-75280