Pre_GI: BLASTP Hits

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Query: NC_012563:2721658:2734700 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2734700, End: 2735857, Length: 1158

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:2584355:2618316261831626194731158Clostridium botulinum Ba4 str. 657 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase0769
NC_014328:1405484:1406681140668114078381158Clostridium ljungdahlii ATCC 49587 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase4e-144511
NC_020291:1464500:1464573146457314657361164Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr8e-136483
NC_012778:841934:8633018633018644431143Eubacterium eligens ATCC 27750, complete genome1-deoxy-D-xylulose-5-phosphate reductoisomerase9e-117420
NC_016627:2799453:2824996282499628261411146Clostridium clariflavum DSM 19732 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase7e-112404
NC_011969:3549000:3568905356890535700471143Bacillus cereus Q1 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase7e-109394
NC_017208:3816753:3837012383701238381541143Bacillus thuringiensis serovar chinensis CT-43 chromosome, complete1-deoxy-D-xylulose 5-phosphate reductoisomerase6e-109394
NC_011772:3787500:3807336380733638084781143Bacillus cereus G9842, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase6e-109394
NC_011725:3821789:3841617384161738427591143Bacillus cereus B4264 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase5e-109394
NC_014171:3701051:3720877372087737220191143Bacillus thuringiensis BMB171 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase5e-109394
NC_005945:3636321:3637594363759436387361143Bacillus anthracis str. Sterne, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-108392
NC_007530:3616828:3637026363702636381681143Bacillus anthracis str. 'Ames Ancestor', complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-108392
NC_006274:3697255:3717452371745237185941143Bacillus cereus E33L, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-108392
NC_003997:3617000:3636899363689936380411143Bacillus anthracis str. Ames, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-108392
NC_012581:559182:6005196005196016611143Bacillus anthracis str. CDC 684 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-108392
NC_012659:3617000:3636926363692636380681143Bacillus anthracis str. A0248, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-108392
NC_011658:3603009:3624943362494336260851143Bacillus cereus AH187 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase4e-108391
NC_003909:3606177:3612297361229736134391143Bacillus cereus ATCC 10987, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase5e-108391
NC_010184:3675424:3695659369565936968011143Bacillus weihenstephanensis KBAB4, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-106386
NC_014624:1549312:1562544156254415636921149Eubacterium limosum KIST612 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-105382
NC_019970:1343670:1362713136271313638611149Thermoanaerobacterium thermosaccharolyticum M0795, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase4e-104378
NC_007907:2879568:2905721290572129068661146Desulfitobacterium hafniense Y51, complete genomehypothetical protein8e-104377
NC_014103:3985897:4007756400775640089041149Bacillus megaterium DSM319 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase1e-98360
NC_005125:2393701:2413353241335324145311179Gloeobacter violaceus PCC 7421, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-97356
NC_011772:3259483:3259483325948332606401158Bacillus cereus G9842, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-97356
NC_004722:3303264:3303264330326433044211158Bacillus cereus ATCC 14579, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase3e-97355
NC_011725:3231859:3231859323185932330161158Bacillus cereus B4264 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase4e-97355
NC_008346:983816:1005959100595910071881230Syntrophomonas wolfei subsp. wolfei str. Goettingen, complete1-deoxy-D-xylulose-5-phosphate reductoisomerase2e-96352
NC_011296:229494:2294942294942306391146Thermodesulfovibrio yellowstonii DSM 11347, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-96352
NC_004663:2509433:2518622251862225197941173Bacteroides thetaiotaomicron VPI-5482, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase5e-96351
NC_007484:882341:8861538861538873341182Nitrosococcus oceani ATCC 19707, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase8e-92337
NC_014315:2485527:2500065250006525012461182Nitrosococcus watsoni C-113 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase8e-91334
NC_014752:131994:1333691333691346041236Neisseria lactamica ST-640, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-89329
NC_010336:1282265:1304074130407413052281155Francisella philomiragia subsp. philomiragia ATCC 25017, complete1-deoxy-D-xylulose-5-phosphate reductoisomerase2e-85316
NC_008601:1560482:1570706157070615718631158Francisella tularensis subsp. novicida U112, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase4e-85315
NC_015064:1268223:1280411128041112816161206Acidobacterium sp. MP5ACTX9 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase5e-85315
NC_004061:237205:2594812594812606771197Buchnera aphidicola str. Sg (Schizaphis graminum), complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase9e-85314
NC_008245:1625715:1635943163594316371001158Francisella tularensis subsp. tularensis FSC 198, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase9e-85313
NC_010677:353839:3617963617963629531158Francisella tularensis subsp. mediasiatica FSC147, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase9e-85313
NC_006570:1625909:1636137163613716372941158Francisella tularensis subsp. tularensis Schu 4, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase9e-85313
NC_009257:338994:3470993470993482561158Francisella tularensis subsp. tularensis WY96-3418 chromosome,1-deoxy-D-xylulose 5-phosphate reductoisomerase9e-85313
NC_016933:1702500:1711887171188717130441158Francisella tularensis TIGB03 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase9e-85313
NC_016937:1625752:1635980163598016371371158Francisella tularensis subsp. tularensis TI0902 chromosome,1-deoxy-D-xylulose 5-phosphate reductoisomerase9e-85313
NC_009749:510266:5183665183665195231158Francisella tularensis subsp. holarctica FTA, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase3e-84312
NC_007880:508407:5165065165065176631158Francisella tularensis subsp. holarctica, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase3e-84312
NC_008369:514995:5202255202255213851161Francisella tularensis subsp. holarctica OSU18, complete genome1-deoxy-D-xylulose-5-phosphate reductoisomerase3e-83309
NC_011985:3380842:3398748339874833999411194Agrobacterium radiobacter K84 chromosome 1, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase5e-83308
NC_015696:798000:8155738155738167271155Francisella sp. TX077308 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-81303
NC_016632:398018:4085624085624097941233Serratia symbiotica str. 'Cinara cedri' chromosome, complete1-deoxy-D-xylulose 5-phosphate reductoisomerase1e-80300
NC_009142:6729512:6729512672951267307051194Saccharopolyspora erythraea NRRL 2338, complete genome1-deoxy-D-xylulose-5-phosphate reductoisomerase1e-79297
NC_013947:5431741:5438685543868554399021218Stackebrandtia nassauensis DSM 44728 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-78293
NC_016781:1408235:1425473142547314266391167Corynebacterium pseudotuberculosis 3/99-5 chromosome, complete1-deoxy-D-xylulose 5-phosphate reductoisomerase1e-76286
NC_017303:1420758:1425358142535814265241167Corynebacterium pseudotuberculosis I19 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-76286
NC_017301:1425293:1425293142529314264591167Corynebacterium pseudotuberculosis C231 chromosome, complete1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-76286
NC_017031:1420738:1425338142533814265041167Corynebacterium pseudotuberculosis P54B96 chromosome, complete1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-76286
NC_014329:1407880:1425535142553514267011167Corynebacterium pseudotuberculosis FRC41 chromosome, complete1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-76286
NC_008358:1789816:1816880181688018180731194Hyphomonas neptunium ATCC 15444, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase8e-74277
NC_010612:2215724:2235392223539222366001209Mycobacterium marinum M, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr2e-73276
NC_020133:2144752:2165845216584521671161272Mycobacterium liflandii 128FXT, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr3e-73275
NC_016790:1480441:1480441148044114816041164Corynebacterium diphtheriae VA01 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-71269
NC_007799:555900:5588515588515600111161Ehrlichia chaffeensis str. Arkansas, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase8e-71267
NC_009380:1491428:1515628151562815168391212Salinispora tropica CNB-440 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase3e-69262
NC_006831:772737:7895627895627907251164Ehrlichia ruminantium str. Gardel, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase9e-68257
NC_006832:776286:7935667935667947291164Ehrlichia ruminantium str. Welgevonden, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase9e-67254
NC_005295:796437:8137178137178148801164Ehrlichia ruminantium str. Welgevonden, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase9e-67254
NC_007797:441782:4574014574014585581158Anaplasma phagocytophilum HZ, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase6e-65248
NC_016148:1105669:1106753110675311078951143Thermovirga lienii DSM 17291 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase8e-61234
NC_009718:1024000:1038417103841710395291113Fervidobacterium nodosum Rt17-B1, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-57223
NC_017095:1333810:1344899134489913460291131Fervidobacterium pennivorans DSM 9078 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase5e-54211
NC_017096:779550:7927347927347938761143Caldisericum exile AZM16c01, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase1e-53210
NC_013009:353690:3712933712933724621170Neorickettsia risticii str. Illinois, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase3e-53209
NC_010003:2134878:2149251214925121504081158Petrotoga mobilis SJ95, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-50199
NC_017200:3221508:322289832228983223230333Bacillus thuringiensis serovar finitimus YBT-020 chromosome,1-deoxy-D-xylulose 5-phosphate reductoisomerase2e-1480.5
NC_011969:3106500:310662731066273106959333Bacillus cereus Q1 chromosome, complete genome1-deoxy-D-xylulose 5-phosphate reductoisomerase8e-1478.2