Pre_GI: BLASTP Hits

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Query: NC_012563:2721658:2721658 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2721658, End: 2722620, Length: 963

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010163:171148:1869271869271893832457Acholeplasma laidlawii PG-8A chromosome, complete genomebifunctional signaling protein/ribosomal protein L92e-0963.5
NC_014166:455378:460415460415461395981Arcobacter nitrofigilis DSM 7299 chromosome, complete genomephosphoesterase RecJ domain-containing protein2e-25116
NC_007530:4400152:441756744175674418499933Bacillus anthracis str. 'Ames Ancestor', complete genomedhh subfamily 1 protein9e-23107
NC_012659:4399094:441746744174674418399933Bacillus anthracis str. A0248, complete genomeDHH subfamily 1 protein9e-23107
NC_003997:4399067:441744044174404418372933Bacillus anthracis str. Ames, complete genomeDHH subfamily 1 protein9e-23107
NC_005945:4399756:441812944181294419061933Bacillus anthracis str. Sterne, complete genomeDHH subfamily 1 protein9e-23107
NC_012472:4400420:441499544149954415927933Bacillus cereus 03BB102, complete genomeDHH subfamily 1 protein9e-23107
NC_011658:4379274:439522443952244396156933Bacillus cereus AH187 chromosome, complete genomeDHH subfamily 1 protein4e-24112
NC_004722:5381208:5394913539491353968861974Bacillus cereus ATCC 14579, complete genomephosphoesterase, DHH family protein6e-0755.1
NC_011725:4562709:4577318457731845783881071Bacillus cereus B4264 chromosome, complete genomeDHH subfamily 1 protein6e-24111
NC_014335:4327584:434594743459474346879933Bacillus cereus biovar anthracis str. CI chromosome, completeDHH family phosphoesterase9e-23107
NC_006274:4448293:446584744658474466779933Bacillus cereus E33L, complete genomephosphoesterase, DHH family3e-23109
NC_016779:4361140:437965443796544380586933Bacillus cereus F837/76 chromosome, complete genome3'-to-5' oligoribonuclease A9e-23107
NC_016771:4333000:434900743490074349939933Bacillus cereus NC7401, complete genomeDHH subfamily 1 protein4e-24112
NC_014171:4447856:446625644662564467188933Bacillus thuringiensis BMB171 chromosome, complete genomeDHH family protein phosphoesterase4e-24112
NC_017200:4401945:442140144214014422333933Bacillus thuringiensis serovar finitimus YBT-020 chromosome,phosphoesterase, DHH family protein8e-24111
NC_014098:1553900:155390015539001554880981Bacillus tusciae DSM 2912 chromosome, complete genomephosphoesterase RecJ domain protein1e-39163
NC_010184:4425676:444299244429924443924933Bacillus weihenstephanensis KBAB4, complete genomephosphoesterase RecJ domain protein1e-22107
NC_008710:621822:649830649830650789960Borrelia turicatae 91E135, complete genomephosphoesterase, DHH family protein3e-1996.3
NC_014387:1175927:118991911899191190875957Butyrivibrio proteoclasticus B316 chromosome 1, complete genomeDHH domain-containing protein4e-28125
NC_014657:944000:958799958799959755957Caldicellulosiruptor owensensis OL chromosome, complete genomephosphoesterase recj domain protein5e-59228
NC_009697:2394826:241917024191702420132963Clostridium botulinum A str. ATCC 19397 chromosome, completeDHH family protein1e-166585
NC_009495:2524000:254714725471472548118972Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeDHH family protein5e-167587
NC_009495:3832500:3866376386637638683611986Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeDHH family protein5e-0652
NC_009698:3706154:3740020374002037420051986Clostridium botulinum A str. Hall chromosome, complete genomeDHH family protein5e-0652
NC_009698:2367171:239151523915152392477963Clostridium botulinum A str. Hall chromosome, complete genomeDHH family protein1e-166585
NC_010520:2585014:260990126099012610863963Clostridium botulinum A3 str. Loch Maree, complete genomeDHH family protein4e-161567
NC_010520:3938490:3972383397238339743681986Clostridium botulinum A3 str. Loch Maree, complete genomeDHH family protein7e-0651.6
NC_010516:3903867:3937733393773339397181986Clostridium botulinum B1 str. Okra, complete genomeDHH family protein5e-0652
NC_010516:2511035:253537025353702536332963Clostridium botulinum B1 str. Okra, complete genomeDHH family protein3e-160564
NC_012658:2584355:260534326053432606305963Clostridium botulinum Ba4 str. 657 chromosome, complete genomeDHH family protein2e-164578
NC_009699:3940984:3974851397485139768361986Clostridium botulinum F str. Langeland chromosome, complete genomeDHH family protein5e-0652
NC_011898:513835:527281527281528243963Clostridium cellulolyticum H10, complete genomephosphoesterase RecJ domain protein6e-50197
NC_016627:2799453:281505628150562816012957Clostridium clariflavum DSM 19732 chromosome, complete genomeexopolyphosphatase-like protein1e-53210
NC_017179:1378875:139097913909791391950972Clostridium difficile BI1, complete genomeRNA-binding protein3e-41169
NC_013315:1370000:1381166138116613821761011Clostridium difficile CD196 chromosome, complete genomeRNA-binding protein4e-41168
NC_014328:1405484:141486114148611415817957Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative phosphoesterase9e-101366
NC_008262:1835613:184995518499551850908954Clostridium perfringens SM101, complete genomeDHH subfamily 1 protein1e-81303
NC_010001:3369500:337568733756873376661975Clostridium phytofermentans ISDg, complete genomephosphoesterase RecJ domain protein2e-29130
NC_014376:3214222:321999732199973220947951Clostridium saccharolyticum WM1 chromosome, complete genomephosphoesterase RecJ domain protein8e-1788.2
NC_020291:1464500:147293414729341473920987Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomebifunctional oligoribonuclease and PAP phosphatase NrnA4e-66251
NC_020134:1173000:118279111827911183735945Clostridium stercorarium subsp. stercorarium DSM 8532, completeRecJ-like phosphoesterase domain-containing protein2e-40166
NC_013170:917177:9171779171779181811005Cryptobacterium curtum DSM 15641, complete genomeexopolyphosphatase-like enzyme8e-26117
NC_011830:3904034:390872439087243909704981Desulfitobacterium hafniense DCB-2, complete genomephosphoesterase RecJ domain protein4e-47188
NC_007907:2879568:288143728814372882417981Desulfitobacterium hafniense Y51, complete genomehypothetical protein7e-47187
NC_013216:3376186:338534533853453386325981Desulfotomaculum acetoxidans DSM 771, complete genomephosphoesterase RecJ domain protein5e-43175
NC_009253:2139379:214557521455752146546972Desulfotomaculum reducens MI-1 chromosome, complete genomephosphoesterase domain-containing protein3e-37155
NC_015589:1899329:192031019203101921281972Desulfotomaculum ruminis DSM 2154 chromosome, complete genomephosphoesterase RecJ domain-containing protein9e-36150
NC_012781:302387:3187723187723209942223Eubacterium rectale ATCC 33656, complete genomeputative phosphatase4e-0962.4
NC_010814:903199:9031999031999058412643Geobacter lovleyi SZ, complete genomeCBS domain containing protein5e-0652.4
NC_009483:2201986:220678622067862207736951Geobacter uraniireducens Rf4 chromosome, complete genomephosphoesterase domain-containing protein2e-34146
NC_015318:706374:718668718668719630963Hippea maritima DSM 10411 chromosome, complete genomephosphoesterase RecJ domain-containing protein2e-31136
NC_017161:775610:781076781076782071996Hydrogenobacter thermophilus TK-6 chromosome, complete genomephosphoesterase RecJ domain-containing protein8e-31134
NC_013799:775619:781085781085782080996Hydrogenobacter thermophilus TK-6, complete genomephosphoesterase RecJ domain protein7e-31134
NC_000908:215000:220607220607221563957Mycoplasma genitalium G37, complete genomephosphoesterase, DHH subfamily 11e-0861.2
NC_000912:175920:179871179871180845975Mycoplasma pneumoniae M129, complete genomeDHH family phosphoesterase1e-1067.4
NC_010003:605961:6256486256486266551008Petrotoga mobilis SJ95, complete genomephosphoesterase RecJ domain protein4e-32138
NC_000961:473077:478695478695479684990Pyrococcus horikoshii OT3, complete genomehypothetical protein2e-0653.5
NC_017098:1278712:130443213044321305430999Spirochaeta africana DSM 8902 chromosome, complete genomeexopolyphosphatase-like protein1e-20100
NC_013928:797714:799557799557800489933Streptococcus mutans NN2025, complete genomehypothetical protein2e-28126
NC_009442:1446508:146522314652231465984762Streptococcus suis 05ZYH33 chromosome, complete genomehypothetical protein2e-23110
NC_009443:1445936:146464314646431465587945Streptococcus suis 98HAH33, complete genomehypothetical protein9e-24110
NC_012926:1496510:151524415152441516188945Streptococcus suis BM407 chromosome, complete genomephosphoesterase6e-24111
NC_012925:1357783:137649613764961377440945Streptococcus suis P1/7, complete genomephosphoesterase9e-24110
NC_012924:1446190:146490414649041465848945Streptococcus suis SC84, complete genomephosphoesterase9e-24110
NC_010730:1519458:153793215379321538924993Sulfurihydrogenibium sp. YO3AOP1, complete genomephosphoesterase RecJ domain protein2e-28126
NC_014152:1430156:144528214452821446262981Thermincola sp. JR, complete genomephosphoesterase RecJ domain protein3e-46185
NC_014964:2301835:2321451232145123234181968Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completephosphoesterase RecJ domain-containing protein5e-0652
NC_014209:2257316:2283643228364322856101968Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,phosphoesterase RecJ domain protein3e-0653.1
NC_010321:2319820:2339436233943623414031968Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completephosphoesterase domain-containing protein5e-0652
NC_019970:1343670:135011213501121351065954Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeexopolyphosphatase-like enzyme6e-58224
NC_005835:1773482:179343717934371794411975Thermus thermophilus HB27, complete genomeexopolyphosphatase family protein3e-27122
NC_014221:3175013:3195474319547431965021029Truepera radiovictrix DSM 17093 chromosome, complete genomephosphoesterase RecJ domain protein4e-1582.4
NC_020419:344000:3564253564253574411017Uncultured Termite group 1 bacterium phylotype Rs-D17 DNA, completeexopolyphosphatase-like protein5e-32138
NS_000191:344000:3564253564253574411017Uncultured Termite group 1 bacterium phylotype Rs-D17, completeexopolyphosphatase-like protein5e-32138